GO:0097295
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morphine biosynthetic process
Biological Process
Definition (GO:0097295 GONUTS page)
The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum. PMID:19567876
Acknowledgement
This term was created by the GO Consortium with support from:
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
morphine synthesis | exact |
morphine biosynthesis | exact |
morphine formation | exact |
morphine anabolism | exact |
Ancestor Chart
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A6A4NPZ7 | 3870 | ITHAT_LUPAL | GO:0009821 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000314, ECO:0000315 from this reference: PMID:37540741 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_output | CHEBI | CHEBI:58097 | morphine(1+) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0097295 based on ALL annotations
The top 26 of 26 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
morphine biosynthetic process
|
39,630,972.00 | 100.00 | 5 | 5 |
1,2-dehydroreticulinium reductase (NADPH) activity
|
39,630,976.00 | 20.00 | 1 | 1 |
salutaridine synthase activity
|
39,630,976.00 | 20.00 | 1 | 1 |
(S)-tetrahydroprotoberberine N-methyltransferase activity
|
5,661,568.00 | 9.09 | 1 | 7 |
salutaridine reductase (NADPH) activity
|
3,602,815.80 | 6.67 | 1 | 11 |
thebaine 6-O-demethylase activity
|
2,830,784.00 | 6.45 | 2 | 28 |
codeine O-demethylase activity
|
501,657.88 | 1.20 | 1 | 79 |
isoquinoline alkaloid biosynthetic process
|
54,103.72 | 0.14 | 2 | 1,465 |
alkaloid metabolic process
|
14,882.08 | 0.04 | 4 | 10,652 |
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
|
1,101.99 | 0.00 | 2 | 71,926 |
Totals | 50 | 109684313 |
No co-occurrence statistics for GO:0097295 based on MANUAL annotations
The top 8 of 8 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
morphine biosynthetic process
|
282,306.60 | 100.00 | 5 | 5 |
thebaine 6-O-demethylase activity
|
282,306.62 | 20.00 | 1 | 1 |
salutaridine synthase activity
|
282,306.62 | 20.00 | 1 | 1 |
salutaridine reductase (NADPH) activity
|
282,306.62 | 20.00 | 1 | 1 |
codeine O-demethylase activity
|
282,306.62 | 20.00 | 1 | 1 |
oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
|
10,857.95 | 3.33 | 1 | 26 |
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
|
858.07 | 0.30 | 1 | 329 |
NADP binding
|
381.50 | 0.13 | 1 | 740 |
Totals | 12 | 1104 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-23 | Deleted | RELATION | is a GO:1901378 (obsolete organic heteropentacyclic compound biosynthetic process) |
2023-12-15 | Deleted | RELATION | is a GO:0044272 (sulfur compound biosynthetic process) |
2022-12-24 | Added | RELATION | is a GO:0044272 (sulfur compound biosynthetic process) |
2012-09-30 | Added | RELATION | is a GO:1901378 (obsolete organic heteropentacyclic compound biosynthetic process) |
2012-05-04 | Added | DEFINITION | The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum. |
2012-05-04 | Added | RELATION | is a GO:0033075 (isoquinoline alkaloid biosynthetic process) |
2012-05-04 | Added | RELATION | is a GO:0071272 (morphine metabolic process) |
2012-05-04 | Added | SYNONYM | morphine formation |
2012-05-04 | Added | SYNONYM | morphine biosynthesis |
2012-05-04 | Added | SYNONYM | morphine synthesis |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-05-04 | Added | TERM | morphine biosynthetic process |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-05-04 | Added | DEFINITION | The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum. |
2012-05-04 | Added | SYNONYM | morphine formation |
2012-05-04 | Added | SYNONYM | morphine biosynthesis |
2012-05-04 | Added | SYNONYM | morphine synthesis |
2012-05-04 | Added | SYNONYM | morphine anabolism |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-23 | Deleted | RELATION | is a GO:1901378 (obsolete organic heteropentacyclic compound biosynthetic process) |
2023-12-15 | Deleted | RELATION | is a GO:0044272 (sulfur compound biosynthetic process) |
2022-12-24 | Added | RELATION | is a GO:0044272 (sulfur compound biosynthetic process) |
2012-09-30 | Added | RELATION | is a GO:1901378 (obsolete organic heteropentacyclic compound biosynthetic process) |
2012-05-04 | Added | RELATION | is a GO:0033075 (isoquinoline alkaloid biosynthetic process) |
2012-05-04 | Added | RELATION | is a GO:0071272 (morphine metabolic process) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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