This term is obsolete.

GO:0098631 JSON

cell adhesion mediator activity

Molecular Function

Definition (GO:0098631 GONUTS page)

The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell.

51,057 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
protein binding involved in cell adhesion exact
cell adhesion molecule exact

Ancestor Chart

Ancestor chart for GO:0098631
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0098631

Child Term Relationship to
GO:0098631
cell adhesion receptor activity
is_a
cell-cell adhesion mediator activity
is_a
cell-matrix adhesion mediator activity
is_a
laminin receptor activity
is_a
integrin complex
capable_of

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P16573-2 10116 CEAM1_RAT GO:0007155 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8454589
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P63026 9913 VAMP2_BOVIN GO:0005515 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699
NOT-qualified manual protein Q86V48 9606 LUZP1_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0005194 obsolete cell adhesion molecule activity consider GO:0098631

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0098631 based on ALL annotations
The top 100 of 300 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cell adhesion mediator activity
259,365.00 100.00 764 764
establishment of protein localization to juxtaparanode region of axon
259,365.00 12.43 95 95
presynaptic membrane organization
246,396.73 12.35 95 100
clustering of voltage-gated potassium channels
123,198.37 10.93 95 200
protein localization to juxtaparanode region of axon
119,032.24 10.84 95 207
positive regulation of adenosine receptor signaling pathway
94,404.89 10.22 95 261
regulation of astrocyte differentiation
90,587.04 10.10 95 272
membrane destabilizing activity
111,882.94 10.00 88 204
alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
259,365.00 9.95 76 76
leukocyte chemotaxis involved in inflammatory response
45,291.13 9.78 139 796
Totals 8175 209074
No co-occurrence statistics for GO:0098631 based on MANUAL annotations
The top 100 of 265 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cell adhesion mediator activity
26,632.70 100.00 53 53
cell aggregation
7,102.05 10.67 8 30
epithelium regeneration
14,526.93 10.34 6 11
maintenance of lens transparency
4,514.02 9.80 10 59
laminin-10 complex
8,877.57 9.23 6 18
trunk neural crest cell migration
8,877.57 7.94 5 15
extracellular matrix of synaptic cleft
8,877.57 7.94 5 15
laminin-5 complex
7,833.15 7.69 5 17
ferroptosis
26,632.70 7.55 4 4
leukocyte chemotaxis involved in inflammatory response
4,842.31 7.50 6 33
Totals 420 9233

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_prokaryote 97
goslim_generic 141

Change Log

Timestamp Action Category Detail
2023-12-15 Added SUBSET goslim_prokaryote
2022-04-22 Deleted DEFINITION The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface, to mediate adhesion of the cell to the external substrate or to another cell.
2022-04-22 Added DEFINITION The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell.
2022-01-12 Added SUBSET goslim_generic
2020-05-22 Added RELATION is a GO:0050839 (cell adhesion molecule binding)
2020-05-22 Deleted RELATION is a GO:0005488 (binding)
2020-05-22 Added DEFINITION The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface, to mediate adhesion of the cell to the external substrate or to another cell.
2020-05-22 Deleted DEFINITION The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell.
2018-03-31 Added DEFINITION The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell.
2018-03-31 Deleted DEFINITION Any binding by a cell surface protein to a molecule external to the cell, that meditates adhesion of the cell to that external substrate.
Timestamp Action Category Detail
2017-09-30 Updated TERM cell adhesion mediator activity
2014-05-11 Added TERM protein binding involved in cell adhesion
Timestamp Action Category Detail
2022-04-22 Deleted DEFINITION The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface, to mediate adhesion of the cell to the external substrate or to another cell.
2022-04-22 Added DEFINITION The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell.
2020-05-22 Added DEFINITION The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface, to mediate adhesion of the cell to the external substrate or to another cell.
2020-05-22 Deleted DEFINITION The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell.
2018-03-31 Added DEFINITION The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell.
2018-03-31 Deleted DEFINITION Any binding by a cell surface protein to a molecule external to the cell, that meditates adhesion of the cell to that external substrate.
2018-03-30 Deleted DEFINITION The binding by a cell-adhesion protein on the cell surface to an extracellular molecule, to meditate adhesion of the cell to the external substrate or to another cell.
2018-03-30 Added DEFINITION Any binding by a cell surface protein to a molecule external to the cell, that meditates adhesion of the cell to that external substrate.
2018-03-29 Deleted DEFINITION Any binding by a cell surface protein to a molecule external to the cell, that meditates adhesion of the cell to that external substrate.
2018-03-29 Added DEFINITION The binding by a cell-adhesion protein on the cell surface to an extracellular molecule, to meditate adhesion of the cell to the external substrate or to another cell.
2017-09-30 Added DEFINITION Any binding by a cell surface protein to a molecule external to the cell, that meditates adhesion of the cell to that external substrate.
2017-09-30 Deleted DEFINITION Any protein binding that is involved in cell adhesion.
2017-09-30 Added SYNONYM protein binding involved in cell adhesion
2017-09-30 Added SYNONYM cell adhesion molecule
2014-05-11 Added DEFINITION Any protein binding that is involved in cell adhesion.
Timestamp Action Category Detail
2020-05-22 Added RELATION is a GO:0050839 (cell adhesion molecule binding)
2020-05-22 Deleted RELATION is a GO:0005488 (binding)
2017-11-15 Deleted RELATION is a GO:0005515 (protein binding)
2017-11-15 Added RELATION is a GO:0005488 (binding)
2015-04-24 Added RELATION part of GO:0007155 (cell adhesion)
2014-05-11 Added RELATION is a GO:0005515 (protein binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
2023-12-15 Added SUBSET goslim_prokaryote
2022-01-12 Added SUBSET goslim_generic
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.