This term is obsolete.

GO:0098992 JSON

neuronal dense core vesicle

Cellular Component

Definition (GO:0098992 GONUTS page)

A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.

2,049 annotations

Ancestor Chart

Ancestor chart for GO:0098992
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0098992

Child Term Relationship to
GO:0098992
neuronal dense core vesicle lumen
part_of
neuronal dense core vesicle membrane
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0098992 neuronal dense core vesicle Only in Taxon 6072 Eumetazoa

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0D1E8X3 237631 A0A0D1E8X3_USTMA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A0G2JZ79 10116 SIR1_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1D8PHF8 237561 A0A1D8PHF8_CANAL GO:0031410 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936
NOT-qualified manual protein A0A1L8G9S0 8355 A0A1L8G9S0_XENLA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4L3K3 6945 A0A1S4L3K3_IXOSC GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A2K5ATM2 6239 A0A2K5ATM2_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5ATM9 6239 A0A2K5ATM9_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
UniProtKB-SubCell SL-0526 Neuronal dense core vesicle

Cross-Ontology Relations

Relation Other Ontology ID Term
part_of CL CL:0000540 neuron

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0098992 based on ALL annotations
The top 100 of 906 co-occurring terms
Co-occurring Term PR S% #Together #Compared
neuronal dense core vesicle
129,184.09 100.00 1,509 1,509
adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation
37,629.31 11.94 254 872
negative regulation of catecholamine secretion
34,388.07 11.77 263 988
heat generation
61,445.73 9.81 166 349
chromaffin granule
17,475.83 8.12 255 1,885
negative regulation of insulin secretion
14,118.48 7.94 340 3,111
diet induced thermogenesis
28,142.47 7.89 166 762
negative regulation of multicellular organism growth
18,794.53 6.68 166 1,141
regulation of systemic arterial blood pressure by norepinephrine-epinephrine
129,184.09 5.83 88 88
positive regulation of mini excitatory postsynaptic potential
122,238.71 5.81 88 93
Totals 11861 323216
No co-occurrence statistics for GO:0098992 based on MANUAL annotations
The top 100 of 789 co-occurring terms
Co-occurring Term PR S% #Together #Compared
neuronal dense core vesicle
18,997.05 100.00 68 68
negative regulation of catecholamine secretion
7,236.97 9.88 8 21
positive regulation of dense core granule biogenesis
10,362.02 8.22 6 11
dense core granule cytoskeletal transport
7,598.82 7.79 6 15
positive regulation of appetite
4,155.60 7.53 7 32
mast cell chemotaxis
6,332.35 7.50 6 18
negative regulation of smooth muscle contraction
3,930.42 6.59 6 29
chromaffin granule
3,676.85 6.45 6 31
adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation
5,587.37 6.25 5 17
mast cell activation
2,191.97 5.26 6 52
Totals 408 4879

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_synapse 357

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
2022-11-22 Deleted DEFINITION A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.
2022-11-22 Added DEFINITION A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.
2019-09-12 Deleted RELATION is a GO:0097458 (obsolete neuron part)
2016-06-15 Added TERM neuronal dense core vesicle
2016-06-15 Added RELATION is a GO:0097458 (obsolete neuron part)
2016-06-15 Added RELATION is a GO:0031045 (dense core granule)
2016-06-15 Added SUBSET goslim_synapse
2016-06-15 Added DEFINITION A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.
Timestamp Action Category Detail
2016-06-15 Added TERM neuronal dense core vesicle
Timestamp Action Category Detail
2022-11-22 Deleted DEFINITION A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.
2022-11-22 Added DEFINITION A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.
2016-06-15 Added DEFINITION A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.
Timestamp Action Category Detail
2019-09-12 Deleted RELATION is a GO:0097458 (obsolete neuron part)
2016-06-15 Added RELATION is a GO:0097458 (obsolete neuron part)
2016-06-15 Added RELATION is a GO:0031045 (dense core granule)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
2016-06-15 Added SUBSET goslim_synapse
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.