This term is obsolete.

GO:0099243 JSON

extrinsic component of synaptic membrane

Cellular Component

Definition (GO:0099243 GONUTS page)

The component of the synaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.

10,441 annotations

Ancestor Chart

Ancestor chart for GO:0099243
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0099243

Child Term Relationship to
GO:0099243
extrinsic component of postsynaptic membrane
is_a
extrinsic component of presynaptic membrane
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Discerning the appropriate spatial relationship between a membrane and a gene product Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0099243 extrinsic component of synaptic membrane Only in Taxon 33208 Metazoa

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 237631 BI1_USTMA GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A022QST3 4155 A0A022QST3_ERYGU GO:0005886 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A022S0M6 4155 A0A022S0M6_ERYGU GO:0005886 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A059AQE2 71139 A0A059AQE2_EUCGR GO:0005886 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A059B0U9 71139 A0A059B0U9_EUCGR GO:0005886 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0099243 based on ALL annotations
The top 53 of 53 co-occurring terms
Co-occurring Term PR S% #Together #Compared
extrinsic component of synaptic membrane
38,987,756.00 100.00 5 5
extrinsic component of postsynaptic density membrane
1,695,119.90 4.08 2 46
regulation of synapse pruning
310,247.40 0.79 3 377
modification of postsynaptic structure
264,622.78 0.68 3 442
atrioventricular valve formation
237,730.22 0.60 2 328
protein localization to mitochondrion
112,681.38 0.29 3 1,038
regulation of axon extension
89,216.84 0.23 2 874
regulation of neuron apoptotic process
75,999.53 0.19 3 1,539
cardiac epithelial to mesenchymal transition
67,452.87 0.17 2 1,156
nervous system process
64,513.66 0.17 3 1,813
Totals 148 67503171
No co-occurrence statistics for GO:0099243 based on MANUAL annotations
The top 42 of 42 co-occurring terms
Co-occurring Term PR S% #Together #Compared
extrinsic component of synaptic membrane
430,599.70 100.00 3 3
NAD+ nucleotidase, cyclic ADP-ribose generating
43,059.97 8.33 1 10
extrinsic component of postsynaptic density membrane
26,912.48 6.06 2 32
atrioventricular valve formation
22,663.14 5.13 2 38
modification of postsynaptic structure
23,922.21 5.00 1 18
NAD+ nucleosidase activity
21,529.98 4.55 1 20
regulation of synapse pruning
17,941.65 3.85 1 24
neuronal signal transduction
12,664.70 2.90 2 68
regulation of axon extension
7,900.91 1.82 2 109
protein localization to mitochondrion
7,689.28 1.72 1 56
Totals 62 397720

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_synapse 357

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2019-09-12 Deleted RELATION is a GO:0044456 (obsolete synapse part)
2018-07-12 Added SUBSET goslim_synapse
2017-07-02 Added RELATION part of GO:0097060 (synaptic membrane)
2017-07-02 Added RELATION is a GO:0044456 (obsolete synapse part)
2017-07-02 Added RELATION is a GO:0019897 (extrinsic component of plasma membrane)
2017-07-02 Added DEFINITION The component of the synaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
2017-07-02 Added TERM extrinsic component of synaptic membrane
Timestamp Action Category Detail
2017-07-02 Added TERM extrinsic component of synaptic membrane
Timestamp Action Category Detail
2017-07-02 Added DEFINITION The component of the synaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
Timestamp Action Category Detail
2019-09-12 Deleted RELATION is a GO:0044456 (obsolete synapse part)
2017-07-02 Added RELATION part of GO:0097060 (synaptic membrane)
2017-07-02 Added RELATION is a GO:0044456 (obsolete synapse part)
2017-07-02 Added RELATION is a GO:0019897 (extrinsic component of plasma membrane)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2018-07-12 Added SUBSET goslim_synapse
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