This term is obsolete.

GO:0099538 JSON

synaptic signaling via neuropeptide

Biological Process

Definition (GO:0099538 GONUTS page)

Cell-cell signaling to or from a synapse, mediated by a peptide.

1,730 annotations

Ancestor Chart

Ancestor chart for GO:0099538
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0099538

Child Term Relationship to
GO:0099538
neuropeptide secretion from presynapse
part_of
trans-synaptic signaling by neuropeptide
is_a

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:

Ontology Development Project
signalling Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0099538 synaptic signaling via neuropeptide Only in Taxon 33208 Metazoa

More information on taxon constraints in GO is available here

Cross-Ontology Relations

Relation Other Ontology ID Term
process_has_causal_agent CHEBI CHEBI:60466 peptide zwitterion

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0099538 based on ALL annotations
The top 100 of 274 co-occurring terms
Co-occurring Term PR S% #Together #Compared
synaptic signaling via neuropeptide
445,291.84 100.00 445 445
G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential
355,416.44 35.58 174 218
G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
445,291.84 18.43 82 82
G protein-coupled receptor dimeric complex
267,797.88 17.13 86 143
GABA receptor activity
193,988.50 15.74 88 202
negative regulation of synaptic plasticity
129,325.67 13.33 88 303
positive regulation of long-term synaptic depression
100,903.56 12.12 92 406
trans-synaptic protein complex
134,880.94 11.91 73 241
ionotropic glutamate receptor complex
95,870.20 10.53 76 353
cellular response to electrical stimulus
67,869.76 9.10 82 538
Totals 6262 752302
No co-occurrence statistics for GO:0099538 based on MANUAL annotations
The top 100 of 245 co-occurring terms
Co-occurring Term PR S% #Together #Compared
synaptic signaling via neuropeptide
78,418.50 100.00 18 18
neuropeptide Y receptor activity
26,139.50 15.38 4 12
phospholipase C-activating G protein-coupled glutamate receptor signaling pathway
29,406.94 13.04 3 8
peptide YY receptor activity
14,936.86 11.43 4 21
G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
78,418.50 11.11 2 2
PLC activating G protein-coupled glutamate receptor activity
39,209.25 10.00 2 4
G protein-coupled receptor dimeric complex
39,209.25 10.00 2 4
trans-synaptic protein complex
13,838.56 9.38 3 17
negative regulation of acute inflammatory response to antigenic stimulus
17,426.33 8.00 2 9
GABA receptor activity
15,683.70 7.69 2 10
Totals 182 5142

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_synapse 357

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2016-01-20 Added DEFINITION Cell-cell signaling to or from a synapse, mediated by a peptide.
2016-01-20 Added RELATION is a GO:0099536 (synaptic signaling)
2016-01-20 Added SUBSET goslim_synapse
2016-01-20 Added TERM synaptic signaling via neuropeptide
Timestamp Action Category Detail
2016-01-20 Added TERM synaptic signaling via neuropeptide
Timestamp Action Category Detail
2016-01-20 Added DEFINITION Cell-cell signaling to or from a synapse, mediated by a peptide.
Timestamp Action Category Detail
2016-01-20 Added RELATION is a GO:0099536 (synaptic signaling)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2016-01-20 Added SUBSET goslim_synapse
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.