This term is obsolete.

GO:0099630 JSON

postsynaptic neurotransmitter receptor cycle

Biological Process

Definition (GO:0099630 GONUTS page)

The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane. PMID:18832033

10 annotations

Ancestor Chart

Ancestor chart for GO:0099630
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0099630 postsynaptic neurotransmitter receptor cycle Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02650 10116 APOE_RAT GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P04639 10116 APOA1_RAT GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P08226 10090 APOE_MOUSE GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076
NOT-qualified manual protein Q00623 10090 APOA1_MOUSE GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0099630 based on ALL annotations
The top 100 of 107 co-occurring terms
Co-occurring Term PR S% #Together #Compared
postsynaptic neurotransmitter receptor cycle
24,367,348.00 100.00 8 8
amylase secretion
24,367,348.00 25.00 2 2
negative regulation of adenylate cyclase activity
2,707,483.20 8.33 2 18
spontaneous synaptic transmission
1,782,976.60 7.14 6 82
neurotransmitter receptor cycle
1,589,174.90 6.38 6 92
postsynaptic recycling endosome membrane
902,494.40 3.33 2 54
postsynaptic endosome
524,029.00 2.11 4 186
positive regulation of endosome to plasma membrane protein transport
270,748.30 1.03 1 90
clustering of voltage-gated potassium channels
243,673.48 0.97 2 200
vesicle-mediated transport in synapse
178,297.66 0.73 6 820
Totals 296 9189670
No co-occurrence statistics for GO:0099630 based on MANUAL annotations
The top 99 of 99 co-occurring terms
Co-occurring Term PR S% #Together #Compared
postsynaptic neurotransmitter receptor cycle
184,542.70 100.00 7 7
neurotransmitter receptor cycle
184,542.72 71.43 5 5
spontaneous synaptic transmission
102,523.73 45.45 5 9
amylase secretion
184,542.72 28.57 2 2
clustering of voltage-gated potassium channels
24,605.70 10.00 2 15
negative regulation of adenylate cyclase activity
20,504.75 8.70 2 18
negative regulation of monoatomic ion transport
30,757.12 8.33 1 6
amyloid precursor protein metabolic process
15,126.45 7.94 5 61
somatodendritic compartment
14,882.48 7.81 5 62
clustering of voltage-gated calcium channels
14,763.42 6.67 2 25
Totals 195 795494

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2022-11-22 Deleted DEFINITION The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane.
2022-11-22 Added DEFINITION The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane.
2020-03-15 Added RELATION is a GO:0051649 (establishment of localization in cell)
2019-08-30 Deleted RELATION is a GO:0051649 (establishment of localization in cell)
2019-05-04 Added RELATION is a GO:0051649 (establishment of localization in cell)
2017-04-07 Deleted RELATION is a GO:0051649 (establishment of localization in cell)
2017-01-21 Deleted SUBSET goslim_synapse
2016-06-03 Added RELATION occurs in GO:0098794 (postsynapse)
2016-06-03 Added RELATION is a GO:0051649 (establishment of localization in cell)
Timestamp Action Category Detail
2016-03-09 Added TERM postsynaptic neurotransmitter receptor cycle
Timestamp Action Category Detail
2022-11-22 Deleted DEFINITION The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane.
2022-11-22 Added DEFINITION The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane.
2016-03-09 Added DEFINITION The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane.
Timestamp Action Category Detail
2020-03-15 Added RELATION is a GO:0051649 (establishment of localization in cell)
2019-08-30 Deleted RELATION is a GO:0051649 (establishment of localization in cell)
2019-05-04 Added RELATION is a GO:0051649 (establishment of localization in cell)
2017-04-07 Deleted RELATION is a GO:0051649 (establishment of localization in cell)
2016-06-03 Added RELATION occurs in GO:0098794 (postsynapse)
2016-06-03 Added RELATION is a GO:0051649 (establishment of localization in cell)
2016-03-09 Added RELATION is a GO:0099627 (neurotransmitter receptor cycle)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2017-01-21 Deleted SUBSET goslim_synapse
2016-03-09 Added SUBSET goslim_synapse
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