GO:0099630
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postsynaptic neurotransmitter receptor cycle
Biological Process
Definition (GO:0099630 GONUTS page)
The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane. PMID:18832033
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0099630 | postsynaptic neurotransmitter receptor cycle | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02650 | 10116 | APOE_RAT | GO:0008104 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P04639 | 10116 | APOA1_RAT | GO:0008104 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P08226 | 10090 | APOE_MOUSE | GO:0008104 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076 | |
NOT-qualified manual | protein | Q00623 | 10090 | APOA1_MOUSE | GO:0008104 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0099630 based on ALL annotations
The top 100 of 107 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
postsynaptic neurotransmitter receptor cycle
|
24,367,348.00 | 100.00 | 8 | 8 |
amylase secretion
|
24,367,348.00 | 25.00 | 2 | 2 |
negative regulation of adenylate cyclase activity
|
2,707,483.20 | 8.33 | 2 | 18 |
spontaneous synaptic transmission
|
1,782,976.60 | 7.14 | 6 | 82 |
neurotransmitter receptor cycle
|
1,589,174.90 | 6.38 | 6 | 92 |
postsynaptic recycling endosome membrane
|
902,494.40 | 3.33 | 2 | 54 |
postsynaptic endosome
|
524,029.00 | 2.11 | 4 | 186 |
positive regulation of endosome to plasma membrane protein transport
|
270,748.30 | 1.03 | 1 | 90 |
clustering of voltage-gated potassium channels
|
243,673.48 | 0.97 | 2 | 200 |
vesicle-mediated transport in synapse
|
178,297.66 | 0.73 | 6 | 820 |
Totals | 296 | 9189670 |
No co-occurrence statistics for GO:0099630 based on MANUAL annotations
The top 99 of 99 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
postsynaptic neurotransmitter receptor cycle
|
184,542.70 | 100.00 | 7 | 7 |
neurotransmitter receptor cycle
|
184,542.72 | 71.43 | 5 | 5 |
spontaneous synaptic transmission
|
102,523.73 | 45.45 | 5 | 9 |
amylase secretion
|
184,542.72 | 28.57 | 2 | 2 |
clustering of voltage-gated potassium channels
|
24,605.70 | 10.00 | 2 | 15 |
negative regulation of adenylate cyclase activity
|
20,504.75 | 8.70 | 2 | 18 |
negative regulation of monoatomic ion transport
|
30,757.12 | 8.33 | 1 | 6 |
amyloid precursor protein metabolic process
|
15,126.45 | 7.94 | 5 | 61 |
somatodendritic compartment
|
14,882.48 | 7.81 | 5 | 62 |
clustering of voltage-gated calcium channels
|
14,763.42 | 6.67 | 2 | 25 |
Totals | 195 | 795494 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2022-11-22 | Deleted | DEFINITION | The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane. |
2022-11-22 | Added | DEFINITION | The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane. |
2020-03-15 | Added | RELATION | is a GO:0051649 (establishment of localization in cell) |
2019-08-30 | Deleted | RELATION | is a GO:0051649 (establishment of localization in cell) |
2019-05-04 | Added | RELATION | is a GO:0051649 (establishment of localization in cell) |
2017-04-07 | Deleted | RELATION | is a GO:0051649 (establishment of localization in cell) |
2017-01-21 | Deleted | SUBSET | goslim_synapse |
2016-06-03 | Added | RELATION | occurs in GO:0098794 (postsynapse) |
2016-06-03 | Added | RELATION | is a GO:0051649 (establishment of localization in cell) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-03-09 | Added | TERM | postsynaptic neurotransmitter receptor cycle |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-11-22 | Deleted | DEFINITION | The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane. |
2022-11-22 | Added | DEFINITION | The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane. |
2016-03-09 | Added | DEFINITION | The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-03-15 | Added | RELATION | is a GO:0051649 (establishment of localization in cell) |
2019-08-30 | Deleted | RELATION | is a GO:0051649 (establishment of localization in cell) |
2019-05-04 | Added | RELATION | is a GO:0051649 (establishment of localization in cell) |
2017-04-07 | Deleted | RELATION | is a GO:0051649 (establishment of localization in cell) |
2016-06-03 | Added | RELATION | occurs in GO:0098794 (postsynapse) |
2016-06-03 | Added | RELATION | is a GO:0051649 (establishment of localization in cell) |
2016-03-09 | Added | RELATION | is a GO:0099627 (neurotransmitter receptor cycle) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2017-01-21 | Deleted | SUBSET | goslim_synapse |
2016-03-09 | Added | SUBSET | goslim_synapse |
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