This term is obsolete.

GO:0102208 JSON

2-polyprenyl-6-hydroxyphenol methylase activity

Molecular Function

Definition (GO:0102208 GONUTS page)

Catalysis of the reaction: a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = a 2-methoxy-6-(all-trans-polyprenyl)phenol + H+ + S-adenosyl-L-homocysteine.

11,868 annotations

Ancestor Chart

Ancestor chart for GO:0102208
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A0A8I6AGH5 10116 A0A8I6AGH5_RAT GO:0008168 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3Z930 10116 D3Z930_RAT GO:0008168 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7KV84 7227 Q7KV84_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7YTX2 7227 Q7YTX2_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593

Cross-references

Database ID Description
EC 2.1.1.222
MetaCyc RXN-12160
RHEA 31411

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:62729 3-(all-trans-polyprenyl)benzene-1,2-diol
has_participant CHEBI CHEBI:59789 S-adenosyl-L-methionine zwitterion
has_participant CHEBI CHEBI:57856 S-adenosyl-L-homocysteine zwitterion
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:62731 2-methoxy-6-(all-trans-polyprenyl)phenol

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0102208 based on ALL annotations
The top 69 of 69 co-occurring terms
Co-occurring Term PR S% #Together #Compared
2-polyprenyl-6-hydroxyphenol methylase activity
16,425.58 100.00 11,868 11,868
3-demethylubiquinol-n 3-O-methyltransferase activity
8,847.33 50.33 10,499 19,492
3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity
7,259.52 41.40 10,296 23,296
ubiquinone biosynthetic process
820.38 4.96 10,513 210,491
methylation
54.07 0.33 11,863 3,603,867
methyltransferase activity
52.11 0.32 11,863 3,739,251
small RNA 2'-O-methyltransferase activity
568.85 0.07 8 231
S-adenosylmethionine-dependent methyltransferase activity
10.49 0.06 386 604,634
intramolecular oxidoreductase activity, interconverting aldoses and ketoses
10.80 0.05 31 47,129
oligosaccharide biosynthetic process
11.08 0.03 7 10,377
Totals 67797 224301786
No co-occurrence statistics for GO:0102208 based on MANUAL annotations
The top 0 of 0 co-occurring terms
Co-occurring Term PR S% #Together #Compared
Totals 0 0

Change Log

Timestamp Action Category Detail
2024-09-19 Added DEFINITION Catalysis of the reaction: a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = a 2-methoxy-6-(all-trans-polyprenyl)phenol + H+ + S-adenosyl-L-homocysteine.
2024-09-19 Deleted DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol = S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2024-09-19 Added XREF EC:2.1.1.222
2023-09-23 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol = S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2023-09-23 Deleted DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2022-11-22 Deleted DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2022-11-22 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2020-06-22 Added XREF RHEA:31411
2020-04-19 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2020-04-19 Deleted DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol
Timestamp Action Category Detail
2017-01-22 Added TERM 2-polyprenyl-6-hydroxyphenol methylase activity
Timestamp Action Category Detail
2024-09-19 Added DEFINITION Catalysis of the reaction: a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = a 2-methoxy-6-(all-trans-polyprenyl)phenol + H+ + S-adenosyl-L-homocysteine.
2024-09-19 Deleted DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol = S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2023-09-23 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol = S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2023-09-23 Deleted DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2022-11-22 Deleted DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2022-11-22 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2020-04-19 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2020-04-19 Deleted DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol
2017-01-22 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol
Timestamp Action Category Detail
2017-01-22 Added RELATION is a GO:0008168 (methyltransferase activity)
Timestamp Action Category Detail
2024-09-19 Added XREF EC:2.1.1.222
2020-06-22 Added XREF RHEA:31411
2017-01-22 Added XREF MetaCyc:RXN-12160
Timestamp Action Category Detail
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