This term is obsolete.

GO:0103012 JSON

ferredoxin-thioredoxin reductase activity

Molecular Function

Definition (GO:0103012 GONUTS page)

Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide. PMID:14769790

Secondary IDs

GO:0030385

915 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ferredoxin:thioredoxin reductase activity exact

Ancestor Chart

Ancestor chart for GO:0103012
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0103012

Child Term Relationship to
GO:0103012
ferredoxin-thioredoxin reductase complex
capable_of

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0103012 ferredoxin-thioredoxin reductase activity Only in Taxon 1117, 33090 Viridiplantae or Cyanobacteria

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 237631 BI1_USTMA GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0MTA1 7955 APEX1_DANRE GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163
NOT-qualified manual protein A7EKP7 665079 A7EKP7_SCLS1 GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884

Cross-references

Database ID Description
EC 1.8.7.2
MetaCyc RXN-9944
RHEA 42336

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:33738 di-mu-sulfido-diiron(1+)
has_participant CHEBI CHEBI:50058 L-cystine residue
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:29950 L-cysteine residue
has_participant CHEBI CHEBI:33737 di-mu-sulfido-diiron(2+)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0103012 based on ALL annotations
The top 20 of 20 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ferredoxin-thioredoxin reductase activity
215,879.05 100.00 903 903
oxidoreductase activity, acting on iron-sulfur proteins as donors
11,816.90 5.47 897 16,387
4 iron, 4 sulfur cluster binding
78.54 0.04 860 2,363,962
oxidoreductase activity
15.70 0.01 866 11,906,003
protein binding
10.32 0.00 2 41,817
chloroplast envelope
9.96 0.00 1 21,678
metal ion binding
7.81 0.00 860 23,771,070
thiosulfate sulfurtransferase activity
6.67 0.00 4 129,396
chloroplast stroma
2.70 0.00 1 79,851
protein-disulfide reductase activity
2.06 0.00 2 209,987
Totals 4433 160888904
No co-occurrence statistics for GO:0103012 based on MANUAL annotations
The top 8 of 8 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ferredoxin-thioredoxin reductase activity
184,542.70 100.00 7 7
4 iron, 4 sulfur cluster binding
874.61 0.47 7 1,477
electron transfer activity
805.86 0.44 7 1,603
photosynthesis
718.07 0.38 1 257
chloroplast envelope
183.44 0.10 1 1,006
chloroplast stroma
74.74 0.04 1 2,469
chloroplast
20.82 0.01 1 8,862
protein binding
8.83 0.00 2 41,817
Totals 27 57498

Change Log

Timestamp Action Category Detail
2024-09-18 Deleted CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2024-09-18 Added CONSTRAINT in_taxon NCBITaxon_Union:2 (Viridiplantae or Cyanobacteria)
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2024-09-05 Deleted CONSTRAINT in_taxon NCBITaxon_Union:2 (Viridiplantae or Cyanobacteria)
2020-12-17 Added CONSTRAINT in_taxon NCBITaxon_Union:2 (Viridiplantae or Cyanobacteria)
2020-12-17 Deleted CONSTRAINT in_taxon NCBITaxon:33090 (Viridiplantae)
2020-11-14 Added CONSTRAINT in_taxon NCBITaxon:33090 (Viridiplantae)
2020-11-14 Added SYNONYM ferredoxin:thioredoxin reductase activity
2020-11-14 Added DEFINITION Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide.
2020-11-14 Deleted DEFINITION Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin.
Timestamp Action Category Detail
2017-06-11 Added TERM ferredoxin-thioredoxin reductase activity
Timestamp Action Category Detail
2020-11-14 Added SYNONYM ferredoxin:thioredoxin reductase activity
2020-11-14 Added DEFINITION Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide.
2020-11-14 Deleted DEFINITION Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin.
2020-04-06 Added DEFINITION Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin.
2020-04-06 Deleted DEFINITION Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin
2017-06-11 Added DEFINITION Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin
Timestamp Action Category Detail
2017-06-11 Added RELATION is a GO:0016673 (oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor)
Timestamp Action Category Detail
2020-02-28 Added XREF RHEA:42336
2017-06-11 Added XREF MetaCyc:RXN-9944
2017-06-11 Added XREF EC:1.8.7.2
Timestamp Action Category Detail
2024-09-18 Deleted CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2024-09-18 Added CONSTRAINT in_taxon NCBITaxon_Union:2 (Viridiplantae or Cyanobacteria)
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2024-09-05 Deleted CONSTRAINT in_taxon NCBITaxon_Union:2 (Viridiplantae or Cyanobacteria)
2020-12-17 Added CONSTRAINT in_taxon NCBITaxon_Union:2 (Viridiplantae or Cyanobacteria)
2020-12-17 Deleted CONSTRAINT in_taxon NCBITaxon:33090 (Viridiplantae)
2020-11-14 Added CONSTRAINT in_taxon NCBITaxon:33090 (Viridiplantae)
2020-11-14 Added SECONDARY GO:0030385 (ferredoxin:thioredoxin reductase activity)
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