GO:0103012
JSON
ferredoxin-thioredoxin reductase activity
Molecular Function
Definition (GO:0103012 GONUTS page)
Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide. PMID:14769790
Secondary IDs
GO:0030385
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
ferredoxin:thioredoxin reductase activity | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0103012
Child Term | Relationship to GO:0103012 |
---|---|
ferredoxin-thioredoxin reductase complex
|
capable_of |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0103012 | ferredoxin-thioredoxin reductase activity | Only in Taxon | 1117, 33090 | Viridiplantae or Cyanobacteria |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 237631 | BI1_USTMA | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.8.7.2 | |
MetaCyc | RXN-9944 | |
RHEA | 42336 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:33738 | di-mu-sulfido-diiron(1+) |
has_participant | CHEBI | CHEBI:50058 | L-cystine residue |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:29950 | L-cysteine residue |
has_participant | CHEBI | CHEBI:33737 | di-mu-sulfido-diiron(2+) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0103012 based on ALL annotations
The top 20 of 20 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ferredoxin-thioredoxin reductase activity
|
215,879.05 | 100.00 | 903 | 903 |
oxidoreductase activity, acting on iron-sulfur proteins as donors
|
11,816.90 | 5.47 | 897 | 16,387 |
4 iron, 4 sulfur cluster binding
|
78.54 | 0.04 | 860 | 2,363,962 |
oxidoreductase activity
|
15.70 | 0.01 | 866 | 11,906,003 |
protein binding
|
10.32 | 0.00 | 2 | 41,817 |
chloroplast envelope
|
9.96 | 0.00 | 1 | 21,678 |
metal ion binding
|
7.81 | 0.00 | 860 | 23,771,070 |
thiosulfate sulfurtransferase activity
|
6.67 | 0.00 | 4 | 129,396 |
chloroplast stroma
|
2.70 | 0.00 | 1 | 79,851 |
protein-disulfide reductase activity
|
2.06 | 0.00 | 2 | 209,987 |
Totals | 4433 | 160888904 |
No co-occurrence statistics for GO:0103012 based on MANUAL annotations
The top 8 of 8 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ferredoxin-thioredoxin reductase activity
|
184,542.70 | 100.00 | 7 | 7 |
4 iron, 4 sulfur cluster binding
|
874.61 | 0.47 | 7 | 1,477 |
electron transfer activity
|
805.86 | 0.44 | 7 | 1,603 |
photosynthesis
|
718.07 | 0.38 | 1 | 257 |
chloroplast envelope
|
183.44 | 0.10 | 1 | 1,006 |
chloroplast stroma
|
74.74 | 0.04 | 1 | 2,469 |
chloroplast
|
20.82 | 0.01 | 1 | 8,862 |
protein binding
|
8.83 | 0.00 | 2 | 41,817 |
Totals | 27 | 57498 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-18 | Deleted | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2024-09-18 | Added | CONSTRAINT | in_taxon NCBITaxon_Union:2 (Viridiplantae or Cyanobacteria) |
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2024-09-05 | Deleted | CONSTRAINT | in_taxon NCBITaxon_Union:2 (Viridiplantae or Cyanobacteria) |
2020-12-17 | Added | CONSTRAINT | in_taxon NCBITaxon_Union:2 (Viridiplantae or Cyanobacteria) |
2020-12-17 | Deleted | CONSTRAINT | in_taxon NCBITaxon:33090 (Viridiplantae) |
2020-11-14 | Added | CONSTRAINT | in_taxon NCBITaxon:33090 (Viridiplantae) |
2020-11-14 | Added | SYNONYM | ferredoxin:thioredoxin reductase activity |
2020-11-14 | Added | DEFINITION | Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide. |
2020-11-14 | Deleted | DEFINITION | Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-06-11 | Added | TERM | ferredoxin-thioredoxin reductase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-11-14 | Added | SYNONYM | ferredoxin:thioredoxin reductase activity |
2020-11-14 | Added | DEFINITION | Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide. |
2020-11-14 | Deleted | DEFINITION | Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin. |
2020-04-06 | Added | DEFINITION | Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin. |
2020-04-06 | Deleted | DEFINITION | Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin |
2017-06-11 | Added | DEFINITION | Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-06-11 | Added | RELATION | is a GO:0016673 (oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Added | XREF | RHEA:42336 |
2017-06-11 | Added | XREF | MetaCyc:RXN-9944 |
2017-06-11 | Added | XREF | EC:1.8.7.2 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-18 | Deleted | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2024-09-18 | Added | CONSTRAINT | in_taxon NCBITaxon_Union:2 (Viridiplantae or Cyanobacteria) |
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2024-09-05 | Deleted | CONSTRAINT | in_taxon NCBITaxon_Union:2 (Viridiplantae or Cyanobacteria) |
2020-12-17 | Added | CONSTRAINT | in_taxon NCBITaxon_Union:2 (Viridiplantae or Cyanobacteria) |
2020-12-17 | Deleted | CONSTRAINT | in_taxon NCBITaxon:33090 (Viridiplantae) |
2020-11-14 | Added | CONSTRAINT | in_taxon NCBITaxon:33090 (Viridiplantae) |
2020-11-14 | Added | SECONDARY | GO:0030385 (ferredoxin:thioredoxin reductase activity) |
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