This term is obsolete.

GO:0110078 JSON

TTT Hsp90 cochaperone complex

Cellular Component

Definition (GO:0110078 GONUTS page)

A Hsp90 cochaperone complex acting as an adapter between Hps90 and its substrates, members of the PIKK kinase family. PMID:20810650 PMID:22505622 PMID:28827813 PMID:34233195

3,029 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
Tel2-Tti1-Tti2 exact
TELO2-TTI1-TTI2 exact
TTT complex exact
Triple T complex exact

Ancestor Chart

Ancestor chart for GO:0110078
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Ancestor chart

Cross-references

Database ID Description
InterPro IPR018870 Tti2 family

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0070209 obsolete ASTRA complex replaced_by GO:0110078

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0110078 based on ALL annotations
The top 100 of 181 co-occurring terms
Co-occurring Term PR S% #Together #Compared
TTT Hsp90 cochaperone complex
65,131.57 100.00 2,993 2,993
ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity
7,445.87 6.37 376 3,289
CTP:tRNA cytidylyltransferase activity
7,441.35 6.36 376 3,291
positive regulation of DNA damage checkpoint
34,736.84 3.37 104 195
tRNA 3'-terminal CCA addition
1,159.40 1.59 379 21,291
regulation of TOR signaling
725.07 0.84 99 8,893
protein localization to chromosome
1,857.36 0.43 15 526
TORC1 complex
313.46 0.42 100 20,778
TORC2 complex
254.70 0.35 100 25,572
cellular response to salt stress
408.09 0.28 15 2,394
Totals 11742 48136641
No co-occurrence statistics for GO:0110078 based on MANUAL annotations
The top 29 of 29 co-occurring terms
Co-occurring Term PR S% #Together #Compared
TTT Hsp90 cochaperone complex
33,123.05 100.00 39 39
positive regulation of DNA damage checkpoint
17,535.73 19.15 9 17
'de novo' cotranslational protein folding
627.93 1.77 8 422
regulation of TOR signaling
619.12 1.61 4 214
TORC1 complex
419.28 1.14 4 316
protein localization to chromosome
649.47 1.12 1 51
TORC2 complex
403.94 1.10 4 328
cellular response to salt stress
466.52 0.92 1 71
Hsp90 protein binding
209.37 0.61 5 791
telomeric DNA binding
141.31 0.41 5 1,172
Totals 152 708211

Change Log

Timestamp Action Category Detail
2023-09-23 Updated TERM TTT Hsp90 cochaperone complex
2023-09-23 Added DEFINITION A Hsp90 cochaperone complex acting as an adapter between Hps90 and its substrates, members of the PIKK kinase family.
2023-09-23 Deleted DEFINITION A protein complex responsible for the stabilisation of protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex can also be found as part of the ASTRA complex (GO:0070209).
2023-09-23 Added SYNONYM TTT complex
2023-09-23 Deleted RELATION has part GO:0070209 (obsolete ASTRA complex)
2021-05-04 Deleted XREF IntAct:EBI-16631004
2018-02-18 Deleted RELATION is a GO:0043234 (protein complex)
2018-02-18 Added RELATION is a GO:0032991 (protein-containing complex)
2018-02-03 Added RELATION has part GO:0070209 (obsolete ASTRA complex)
2018-01-31 Added RELATION capable of part of GO:2000003 (positive regulation of DNA damage checkpoint)
Timestamp Action Category Detail
2023-09-23 Updated TERM TTT Hsp90 cochaperone complex
2018-01-31 Added TERM TTT complex
Timestamp Action Category Detail
2023-09-23 Added DEFINITION A Hsp90 cochaperone complex acting as an adapter between Hps90 and its substrates, members of the PIKK kinase family.
2023-09-23 Deleted DEFINITION A protein complex responsible for the stabilisation of protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex can also be found as part of the ASTRA complex (GO:0070209).
2023-09-23 Added SYNONYM TTT complex
2018-01-31 Added DEFINITION A protein complex responsible for the stabilisation of protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex can also be found as part of the ASTRA complex (GO:0070209).
2018-01-31 Added SYNONYM Tel2-Tti1-Tti2
2018-01-31 Added SYNONYM Triple T complex
2018-01-31 Added SYNONYM TELO2-TTI1-TTI2
Timestamp Action Category Detail
2023-09-23 Deleted RELATION has part GO:0070209 (obsolete ASTRA complex)
2018-02-18 Deleted RELATION is a GO:0043234 (protein complex)
2018-02-18 Added RELATION is a GO:0032991 (protein-containing complex)
2018-02-03 Added RELATION has part GO:0070209 (obsolete ASTRA complex)
2018-01-31 Added RELATION capable of part of GO:2000003 (positive regulation of DNA damage checkpoint)
2018-01-31 Added RELATION capable of part of GO:0050821 (protein stabilization)
2018-01-31 Added RELATION is a GO:0043234 (protein complex)
Timestamp Action Category Detail
2021-05-04 Deleted XREF IntAct:EBI-16631004
2018-01-31 Added XREF IntAct:EBI-16631004
Timestamp Action Category Detail
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