GO:0110078
JSON
TTT Hsp90 cochaperone complex
Cellular Component
Definition (GO:0110078 GONUTS page)
A Hsp90 cochaperone complex acting as an adapter between Hps90 and its substrates, members of the PIKK kinase family. PMID:20810650 PMID:22505622 PMID:28827813 PMID:34233195
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
Tel2-Tti1-Tti2 | exact |
TELO2-TTI1-TTI2 | exact |
TTT complex | exact |
Triple T complex | exact |
Ancestor Chart
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR018870 | Tti2 family |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0070209 | obsolete ASTRA complex | replaced_by GO:0110078 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0110078 based on ALL annotations
The top 100 of 181 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
TTT Hsp90 cochaperone complex
|
65,131.57 | 100.00 | 2,993 | 2,993 |
ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity
|
7,445.87 | 6.37 | 376 | 3,289 |
CTP:tRNA cytidylyltransferase activity
|
7,441.35 | 6.36 | 376 | 3,291 |
positive regulation of DNA damage checkpoint
|
34,736.84 | 3.37 | 104 | 195 |
tRNA 3'-terminal CCA addition
|
1,159.40 | 1.59 | 379 | 21,291 |
regulation of TOR signaling
|
725.07 | 0.84 | 99 | 8,893 |
protein localization to chromosome
|
1,857.36 | 0.43 | 15 | 526 |
TORC1 complex
|
313.46 | 0.42 | 100 | 20,778 |
TORC2 complex
|
254.70 | 0.35 | 100 | 25,572 |
cellular response to salt stress
|
408.09 | 0.28 | 15 | 2,394 |
Totals | 11742 | 48136641 |
No co-occurrence statistics for GO:0110078 based on MANUAL annotations
The top 29 of 29 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
TTT Hsp90 cochaperone complex
|
33,123.05 | 100.00 | 39 | 39 |
positive regulation of DNA damage checkpoint
|
17,535.73 | 19.15 | 9 | 17 |
'de novo' cotranslational protein folding
|
627.93 | 1.77 | 8 | 422 |
regulation of TOR signaling
|
619.12 | 1.61 | 4 | 214 |
TORC1 complex
|
419.28 | 1.14 | 4 | 316 |
protein localization to chromosome
|
649.47 | 1.12 | 1 | 51 |
TORC2 complex
|
403.94 | 1.10 | 4 | 328 |
cellular response to salt stress
|
466.52 | 0.92 | 1 | 71 |
Hsp90 protein binding
|
209.37 | 0.61 | 5 | 791 |
telomeric DNA binding
|
141.31 | 0.41 | 5 | 1,172 |
Totals | 152 | 708211 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-23 | Updated | TERM | TTT Hsp90 cochaperone complex |
2023-09-23 | Added | DEFINITION | A Hsp90 cochaperone complex acting as an adapter between Hps90 and its substrates, members of the PIKK kinase family. |
2023-09-23 | Deleted | DEFINITION | A protein complex responsible for the stabilisation of protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex can also be found as part of the ASTRA complex (GO:0070209). |
2023-09-23 | Added | SYNONYM | TTT complex |
2023-09-23 | Deleted | RELATION | has part GO:0070209 (obsolete ASTRA complex) |
2021-05-04 | Deleted | XREF | IntAct:EBI-16631004 |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2018-02-18 | Added | RELATION | is a GO:0032991 (protein-containing complex) |
2018-02-03 | Added | RELATION | has part GO:0070209 (obsolete ASTRA complex) |
2018-01-31 | Added | RELATION | capable of part of GO:2000003 (positive regulation of DNA damage checkpoint) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-23 | Updated | TERM | TTT Hsp90 cochaperone complex |
2018-01-31 | Added | TERM | TTT complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-23 | Added | DEFINITION | A Hsp90 cochaperone complex acting as an adapter between Hps90 and its substrates, members of the PIKK kinase family. |
2023-09-23 | Deleted | DEFINITION | A protein complex responsible for the stabilisation of protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex can also be found as part of the ASTRA complex (GO:0070209). |
2023-09-23 | Added | SYNONYM | TTT complex |
2018-01-31 | Added | DEFINITION | A protein complex responsible for the stabilisation of protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex can also be found as part of the ASTRA complex (GO:0070209). |
2018-01-31 | Added | SYNONYM | Tel2-Tti1-Tti2 |
2018-01-31 | Added | SYNONYM | Triple T complex |
2018-01-31 | Added | SYNONYM | TELO2-TTI1-TTI2 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-23 | Deleted | RELATION | has part GO:0070209 (obsolete ASTRA complex) |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2018-02-18 | Added | RELATION | is a GO:0032991 (protein-containing complex) |
2018-02-03 | Added | RELATION | has part GO:0070209 (obsolete ASTRA complex) |
2018-01-31 | Added | RELATION | capable of part of GO:2000003 (positive regulation of DNA damage checkpoint) |
2018-01-31 | Added | RELATION | capable of part of GO:0050821 (protein stabilization) |
2018-01-31 | Added | RELATION | is a GO:0043234 (protein complex) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-04 | Deleted | XREF | IntAct:EBI-16631004 |
2018-01-31 | Added | XREF | IntAct:EBI-16631004 |
Timestamp | Action | Category | Detail |
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