This term is obsolete.
Note that this term excludes activities for which a charged tRNA acts as an amino acid donor.

GO:0140101 JSON

catalytic activity, acting on a tRNA

Molecular Function

Definition (GO:0140101 GONUTS page)

Catalytic activity that acts to modify a tRNA.

Comments

Note that this term excludes activities for which a charged tRNA acts as an amino acid donor.

4,852,528 annotations

Ancestor Chart

Ancestor chart for GO:0140101
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0140101

Child Term Relationship to
GO:0140101
aminoacyl-tRNA ligase activity
is_a
glutamyl-tRNA reductase activity
is_a
tRNA methyltransferase activity
is_a
CCA tRNA nucleotidyltransferase activity
is_a
tRNA adenosine(64)-2'-O-ribosylphosphate transferase activity
is_a
tRNA-uridine 2-sulfurtransferase activity
is_a
tRNA demethylase activity
is_a
tRNA guanylyltransferase activity
is_a
aminoacyl-tRNA hydrolase activity
is_a
tRNA dimethylallyltransferase activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:17843 transfer RNA

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0140101 based on ALL annotations
The top 100 of 275 co-occurring terms
Co-occurring Term PR S% #Together #Compared
catalytic activity, acting on a tRNA
1,497.43 100.00 130,182 130,182
tRNA aminoacylation for protein translation
509.68 34.00 129,800 381,347
threonyl-tRNA aminoacylation
1,083.19 30.50 44,949 62,139
threonine-tRNA ligase activity
1,065.28 30.30 44,965 63,206
histidine-tRNA ligase activity
832.43 24.77 40,207 72,327
histidyl-tRNA aminoacylation
834.54 24.68 39,957 71,696
proline-tRNA ligase activity
524.89 12.82 21,888 62,443
prolyl-tRNA aminoacylation
526.48 12.82 21,850 62,147
glycyl-tRNA aminoacylation
400.30 11.03 20,568 76,940
glycine-tRNA ligase activity
392.57 10.95 20,594 78,554
Totals 1169824 147451240
No co-occurrence statistics for GO:0140101 based on MANUAL annotations
The top 17 of 17 co-occurring terms
Co-occurring Term PR S% #Together #Compared
catalytic activity, acting on a tRNA
258,359.80 100.00 5 5
Cdc48p-Npl4p-Vms1p AAA ATPase complex
43,059.97 10.00 1 6
mitochondria-associated ubiquitin-dependent protein catabolic process
18,454.27 5.56 1 14
nuclear protein quality control by the ubiquitin-proteasome system
4,306.00 1.56 1 60
cellular response to hydrogen peroxide
2,514.45 0.97 4 411
rescue of stalled ribosome
1,590.89 0.62 5 812
protein quality control for misfolded or incompletely synthesized proteins
1,108.84 0.43 5 1,165
aminoacyl-tRNA hydrolase activity
559.22 0.21 1 462
RNA endonuclease activity
484.00 0.19 5 2,669
ERAD pathway
233.65 0.09 4 4,423
Totals 45 445447

Change Log

Timestamp Action Category Detail
2017-09-19 Added RELATION is a GO:0140098 (catalytic activity, acting on RNA)
2017-09-19 Added DEFINITION Catalytic activity that acts to modify a tRNA.
2017-09-19 Added TERM catalytic activity, acting on a tRNA
Timestamp Action Category Detail
2017-09-19 Added TERM catalytic activity, acting on a tRNA
Timestamp Action Category Detail
2017-09-19 Added DEFINITION Catalytic activity that acts to modify a tRNA.
Timestamp Action Category Detail
2017-09-19 Added RELATION is a GO:0140098 (catalytic activity, acting on RNA)
Timestamp Action Category Detail
Timestamp Action Category Detail
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