GO:0140227
JSON
serotonin-gated cation-selective signaling pathway
Biological Process
Definition (GO:0140227 GONUTS page)
The series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. PMID:25392484 PMID:27764665
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
5-HT-gated cation-selective signaling pathway | exact |
5-HT-gated cation-selective signalling pathway | exact |
serotonin-gated cation-selective signalling pathway | exact |
5-hydroxytryptamine-gated cation-selective signaling pathway | exact |
5-hydroxytryptamine-gated cation-selective signalling pathway | exact |
Ancestor Chart
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
Ontology Development Project | |
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signalling | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0140227 | serotonin-gated cation-selective signaling pathway | Only in Taxon | 33208 | Metazoa |
More information on taxon constraints in GO is available here
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0140227 based on ALL annotations
The top 39 of 39 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
serotonin-gated cation-selective signaling pathway
|
544,381.50 | 100.00 | 364 | 364 |
serotonin-activated cation-selective channel complex
|
542,890.06 | 99.73 | 364 | 365 |
serotonin-gated monoatomic cation channel activity
|
388,538.97 | 71.37 | 364 | 510 |
serotonin receptor signaling pathway
|
32,056.11 | 5.68 | 224 | 3,804 |
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
|
33,053.16 | 5.04 | 83 | 1,367 |
excitatory extracellular ligand-gated monoatomic ion channel activity
|
31,669.99 | 3.84 | 37 | 636 |
regulation of presynaptic membrane potential
|
22,445.93 | 3.62 | 83 | 2,013 |
serotonin binding
|
11,022.91 | 1.90 | 88 | 4,346 |
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
|
6,507.95 | 1.08 | 37 | 3,095 |
extracellular ligand-gated monoatomic ion channel activity
|
3,047.71 | 0.56 | 342 | 61,088 |
Totals | 4692 | 80073406 |
No co-occurrence statistics for GO:0140227 based on MANUAL annotations
The top 29 of 29 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
serotonin-gated cation-selective signaling pathway
|
201,647.58 | 100.00 | 7 | 7 |
serotonin-activated cation-selective channel complex
|
156,837.00 | 77.78 | 7 | 9 |
serotonin receptor signaling pathway
|
8,933.75 | 4.43 | 7 | 158 |
serotonin-gated monoatomic cation channel activity
|
7,629.91 | 3.78 | 7 | 185 |
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
|
4,689.48 | 2.04 | 1 | 43 |
transmembrane transporter complex
|
2,673.36 | 1.33 | 7 | 528 |
serotonin binding
|
2,536.45 | 1.22 | 2 | 159 |
excitatory extracellular ligand-gated monoatomic ion channel activity
|
2,295.18 | 1.14 | 7 | 615 |
inorganic cation transmembrane transport
|
1,387.94 | 0.69 | 7 | 1,017 |
behavioral response to ethanol
|
1,390.67 | 0.66 | 1 | 145 |
Totals | 121 | 236444 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33208 (Metazoa) |
2022-03-14 | Added | DEFINITION | The series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. |
2022-03-14 | Deleted | DEFINITION | A series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-274 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-276 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-271 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-272 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-275 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-278 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-277 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-06-08 | Added | TERM | serotonin-gated cation-selective signaling pathway |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-03-14 | Added | DEFINITION | The series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. |
2022-03-14 | Deleted | DEFINITION | A series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. |
2018-06-08 | Added | SYNONYM | serotonin-gated cation-selective signalling pathway |
2018-06-08 | Added | SYNONYM | 5-HT-gated cation-selective signalling pathway |
2018-06-08 | Added | SYNONYM | 5-hydroxytryptamine-gated cation-selective signalling pathway |
2018-06-08 | Added | SYNONYM | 5-HT-gated cation-selective signaling pathway |
2018-06-08 | Added | DEFINITION | A series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. |
2018-06-08 | Added | SYNONYM | 5-hydroxytryptamine-gated cation-selective signaling pathway |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-06-08 | Added | RELATION | is a GO:0007210 (serotonin receptor signaling pathway) |
2018-06-08 | Added | RELATION | is a GO:1990806 (ligand-gated ion channel signaling pathway) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-274 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-276 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-271 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-272 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-275 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-278 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-277 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-273 |
2021-05-04 | Deleted | XREF | ComplexPortal:CPX-2175 |
2018-06-08 | Added | XREF | ComplexPortal:CPX-275 |
2018-06-08 | Added | XREF | ComplexPortal:CPX-272 |
2018-06-08 | Added | XREF | ComplexPortal:CPX-271 |
2018-06-08 | Added | XREF | ComplexPortal:CPX-276 |
2018-06-08 | Added | XREF | ComplexPortal:CPX-274 |
2018-06-08 | Added | XREF | ComplexPortal:CPX-273 |
2018-06-08 | Added | XREF | ComplexPortal:CPX-2175 |
2018-06-08 | Added | XREF | ComplexPortal:CPX-277 |
2018-06-08 | Added | XREF | ComplexPortal:CPX-278 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33208 (Metazoa) |
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