GO:0140292
JSON
ADP-ribosylserine hydrolase activity
Molecular Function
Definition (GO:0140292 GONUTS page)
Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose. PMID:28650317 PMID:29234005
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | E9PTA2 | 10116 | TRPM2_RAT | GO:0016787 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | O94759 | 9606 | TRPM2_HUMAN | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q62226 | 10090 | SHH_MOUSE | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113 | |
NOT-qualified manual | protein | Q63673 | 10116 | SHH_RAT | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q91YD4 | 10090 | TRPM2_MOUSE | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q93Y07 | 3702 | SFR2_ARATH | GO:0016798 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25100720 |
Cross-references
Database | ID | Description |
---|---|---|
RHEA | 58256 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:57967 | ADP-D-ribose(2-) |
has_participant | CHEBI | CHEBI:29999 | L-serine residue |
has_participant | CHEBI | CHEBI:15377 | water |
has_participant | CHEBI | CHEBI:142556 | O-(ADP-D-ribosyl)-L-serine(2-) residue |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0140292 based on ALL annotations
The top 36 of 36 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ADP-ribosylserine hydrolase activity
|
1,756,205.20 | 100.00 | 111 | 111 |
peptidyl-serine ADP-deribosylation
|
1,756,205.40 | 89.19 | 99 | 99 |
cellular response to superoxide
|
1,602,750.40 | 78.33 | 94 | 103 |
negative regulation of necroptotic process
|
70,832.40 | 4.01 | 97 | 2,405 |
O-acetyl-ADP-ribose deacetylase activity
|
43,593.75 | 2.47 | 98 | 3,948 |
female germ-line stem cell population maintenance
|
53,513.18 | 2.39 | 11 | 361 |
poly(ADP-ribose) glycohydrolase activity
|
35,488.58 | 2.02 | 111 | 5,493 |
site of DNA damage
|
33,442.76 | 1.90 | 109 | 5,724 |
ADP-D-ribose binding
|
14,395.13 | 0.43 | 1 | 122 |
Cajal body organization
|
7,493.51 | 0.41 | 11 | 2,578 |
Totals | 1942 | 141455159 |
No co-occurrence statistics for GO:0140292 based on MANUAL annotations
The top 30 of 30 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ADP-ribosylserine hydrolase activity
|
129,179.90 | 100.00 | 10 | 10 |
peptidyl-serine ADP-deribosylation
|
114,826.58 | 72.73 | 8 | 9 |
O-acetyl-ADP-ribose deacetylase activity
|
41,337.57 | 29.63 | 8 | 25 |
cellular response to superoxide
|
43,059.97 | 22.22 | 4 | 12 |
negative regulation of necroptotic process
|
10,033.39 | 7.62 | 8 | 103 |
poly(ADP-ribose) glycohydrolase activity
|
8,970.83 | 6.94 | 10 | 144 |
ADP-D-ribose binding
|
9,936.92 | 4.55 | 1 | 13 |
site of DNA damage
|
4,506.28 | 3.47 | 9 | 258 |
female germ-line stem cell population maintenance
|
2,748.51 | 1.79 | 1 | 47 |
hydrolase activity, hydrolyzing O-glycosyl compounds
|
2,227.24 | 1.72 | 8 | 464 |
Totals | 120 | 503956 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-13 | Added | XREF | RHEA:58256 |
2023-06-24 | Added | RELATION | is a GO:0140096 (catalytic activity, acting on a protein) |
2018-11-25 | Added | DEFINITION | Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose. |
2018-11-25 | Added | TERM | ADP-ribosylserine hydrolase activity |
2018-11-25 | Added | RELATION | is a GO:0016799 (hydrolase activity, hydrolyzing N-glycosyl compounds) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-11-25 | Added | TERM | ADP-ribosylserine hydrolase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-11-25 | Added | DEFINITION | Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-06-24 | Added | RELATION | is a GO:0140096 (catalytic activity, acting on a protein) |
2018-11-25 | Added | RELATION | is a GO:0016799 (hydrolase activity, hydrolyzing N-glycosyl compounds) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-13 | Added | XREF | RHEA:58256 |
Timestamp | Action | Category | Detail |
---|
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link