This term is obsolete.

GO:0140292 JSON

ADP-ribosylserine hydrolase activity

Molecular Function

Definition (GO:0140292 GONUTS page)

Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose. PMID:28650317 PMID:29234005

125 annotations

Ancestor Chart

Ancestor chart for GO:0140292
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein E9PTA2 10116 TRPM2_RAT GO:0016787 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein O94759 9606 TRPM2_HUMAN GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q62226 10090 SHH_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113
NOT-qualified manual protein Q63673 10116 SHH_RAT GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q91YD4 10090 TRPM2_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q93Y07 3702 SFR2_ARATH GO:0016798 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25100720

Cross-references

Database ID Description
RHEA 58256

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:15377 water
has_participant CHEBI CHEBI:29999 L-serine residue
has_participant CHEBI CHEBI:57967 ADP-D-ribose(2-)
has_participant CHEBI CHEBI:142556 O-(ADP-D-ribosyl)-L-serine(2-) residue

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0140292 based on ALL annotations
The top 36 of 36 co-occurring terms
Co-occurring Term PR S% #Together #Compared
1,785,179.00 100.00 111 111
1,785,178.90 89.19 99 99
1,629,192.20 78.33 94 103
71,377.73 3.98 97 2,426
43,747.82 2.44 98 3,999
54,245.77 2.38 11 362
34,666.70 1.94 111 5,716
33,520.16 1.88 109 5,805
14,753.55 0.43 1 121
7,362.94 0.40 11 2,667
Totals 1961 141786110
No co-occurrence statistics for GO:0140292 based on MANUAL annotations
The top 30 of 30 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ADP-ribosylserine hydrolase activity
141,153.30 100.00 10 10
peptidyl-serine ADP-deribosylation
125,469.61 72.73 8 9
O-acetyl-ADP-ribose deacetylase activity
56,461.32 36.36 8 20
cellular response to superoxide
47,051.10 22.22 4 12
negative regulation of necroptotic process
10,265.69 7.14 8 110
poly(ADP-ribose) glycohydrolase activity
9,286.40 6.58 10 152
ADP-D-ribose binding
11,762.78 4.76 1 12
site of DNA damage
4,867.36 3.44 9 261
female germ-line stem cell population maintenance
3,003.26 1.79 1 47
hydrolase activity, hydrolyzing O-glycosyl compounds
2,227.27 1.57 8 507
Totals 120 544023

Change Log

Timestamp Action Category Detail
2024-07-13 Added XREF RHEA:58256
2023-06-24 Added RELATION is a GO:0140096 (catalytic activity, acting on a protein)
2018-11-25 Added DEFINITION Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose.
2018-11-25 Added RELATION is a GO:0016799 (hydrolase activity, hydrolyzing N-glycosyl compounds)
2018-11-25 Added TERM ADP-ribosylserine hydrolase activity
Timestamp Action Category Detail
2018-11-25 Added TERM ADP-ribosylserine hydrolase activity
Timestamp Action Category Detail
2018-11-25 Added DEFINITION Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose.
Timestamp Action Category Detail
2023-06-24 Added RELATION is a GO:0140096 (catalytic activity, acting on a protein)
2018-11-25 Added RELATION is a GO:0016799 (hydrolase activity, hydrolyzing N-glycosyl compounds)
Timestamp Action Category Detail
2024-07-13 Added XREF RHEA:58256
Timestamp Action Category Detail
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