This term is obsolete.

GO:0140294 JSON

NAD DNA ADP-ribosyltransferase activity

Molecular Function

Definition (GO:0140294 GONUTS page)

Catalysis of the transfer of the ADP-ribose group of NAD+ to a residue in double-stranded DNA. PMID:27471034 PMID:29361132 PMID:29520010

274 annotations

Ancestor Chart

Ancestor chart for GO:0140294
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0140294

Child Term Relationship to
GO:0140294
2'-deoxyguanosine DNA ADP-ribosyltransferase activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016757 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A6KJI3 10116 A6KJI3_RAT GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D6WQD5 7070 D6WQD5_TRICA GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q6AYL7 10116 Q6AYL7_RAT GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7JRM5 7227 Q7JRM5_DROME GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0140294 based on ALL annotations
The top 100 of 138 co-occurring terms
Co-occurring Term PR S% #Together #Compared
NAD DNA ADP-ribosyltransferase activity
732,852.56 100.00 266 266
DNA ADP-ribosylation
597,971.75 81.60 266 326
NAD+-protein-glutamate ADP-ribosyltransferase activity
529,724.94 72.28 266 368
NAD+-protein-serine ADP-ribosyltransferase activity
697,769.20 65.09 179 188
regulation of base-excision repair
732,852.56 36.47 97 97
negative regulation of isotype switching
732,852.56 31.58 84 84
positive regulation of single strand break repair
388,451.94 27.56 97 183
protein auto-ADP-ribosylation
195,329.45 26.65 266 998
negative regulation of ATP biosynthetic process
360,846.20 26.50 97 197
NAD+-protein-lysine ADP-ribosyltransferase activity
335,569.30 23.58 87 190
Totals 8749 4728617
No co-occurrence statistics for GO:0140294 based on MANUAL annotations
The top 100 of 127 co-occurring terms
Co-occurring Term PR S% #Together #Compared
NAD DNA ADP-ribosyltransferase activity
99,369.16 100.00 13 13
DNA ADP-ribosylation
56,165.18 56.52 13 23
NAD+-protein-glutamate ADP-ribosyltransferase activity
54,201.36 52.17 12 22
negative regulation of isotype switching
99,369.16 38.46 5 5
NAD+-protein-serine ADP-ribosyltransferase activity
49,684.58 38.10 8 16
NAD+-protein-aspartate ADP-ribosyltransferase activity
37,263.43 36.36 12 32
NAD+-protein-lysine ADP-ribosyltransferase activity
56,782.38 25.00 4 7
protein auto-ADP-ribosylation
21,680.54 21.43 12 55
hippocampal neuron apoptotic process
36,134.24 20.00 4 11
NAD+-histone H2BS6 serine ADP-ribosyltransferase activity
99,369.16 15.38 2 2
Totals 350 40454

Change Log

Timestamp Action Category Detail
2018-11-25 Added TERM NAD DNA ADP-ribosyltransferase activity
2018-11-25 Added DEFINITION Catalysis of the transfer of the ADP-ribose group of NAD+ to a residue in double-stranded DNA.
2018-11-25 Added RELATION is a GO:0016763 (pentosyltransferase activity)
Timestamp Action Category Detail
2018-11-25 Added TERM NAD DNA ADP-ribosyltransferase activity
Timestamp Action Category Detail
2018-11-25 Added DEFINITION Catalysis of the transfer of the ADP-ribose group of NAD+ to a residue in double-stranded DNA.
Timestamp Action Category Detail
2018-11-25 Added RELATION is a GO:0016763 (pentosyltransferase activity)
Timestamp Action Category Detail
Timestamp Action Category Detail
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