This term is obsolete.

GO:0140359 JSON

ABC-type transporter activity

Molecular Function

Definition (GO:0140359 GONUTS page)

Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. PMID:26517899

1,724,712 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ABC-type transmembrane transporter activity exact
ABC-type efflux permease activity exact
ABC-type uptake permease activity exact
ATP binding cassette transporter exact
ABC-type efflux porter activity exact
ATP-binding cassette transporter exact
ATP-binding cassette (ABC) transporter activity exact
ABC transporter exact

Ancestor Chart

Ancestor chart for GO:0140359
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0140359

Child Term Relationship to
GO:0140359
ABC-type 3',5'-cyclic GMP transmembrane transporter activity
is_a
ABC-type phytochelatin transporter activity
is_a
ABC-type zinc transporter activity
is_a
ABC-type vitamin B12 transporter activity
is_a
ABC-type oligopeptide transporter activity
is_a
ABC-type amino acid transporter activity
is_a
ABC-type sodium transporter activity
is_a
ABC-type guanine transporter activity
is_a
ABC-type ferric iron transporter activity
is_a
ABC-type carbohydrate transporter activity
is_a

Cross-references

Database ID Description
InterPro IPR000412 ABC-2 transporter
InterPro IPR005951 Retinal-specific ATP-binding cassette transporter
InterPro IPR011527 ABC transporter type 1, transmembrane domain
InterPro IPR011868 Molybdate ABC transporter, ATP-binding protein
InterPro IPR013525 ABC-2 type transporter, transmembrane domain
InterPro IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD
InterPro IPR015855 ABC transporter, maltose/maltodextrin import, MalK-like
InterPro IPR015860 ABC transporter, teichoic acids export TagH-like
InterPro IPR026082 ABC transporter A
InterPro IPR032688 ABC-2 type transporter permease protein NosY/YtrC-like

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0140359 based on ALL annotations
The top 100 of 2,889 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ABC-type transporter activity
190.70 100.00 1,039,068 1,039,068
ABC-type oligopeptide transporter activity
178.24 24.79 262,157 280,492
oligopeptide transmembrane transport
151.42 19.25 210,492 265,097
ATPase-coupled transmembrane transporter activity
122.84 17.37 199,635 309,938
lipid transport
81.19 11.42 140,271 329,484
ATP hydrolysis activity
20.65 10.31 711,178 6,567,693
ATPase-coupled lipid transmembrane transporter activity
177.06 10.27 107,526 115,812
transmembrane transport
18.68 9.78 1,027,002 10,486,863
ATP-binding cassette (ABC) transporter complex
31.57 9.16 176,873 1,068,316
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
89.39 6.18 69,108 147,440
Totals 7016305 154692313
No co-occurrence statistics for GO:0140359 based on MANUAL annotations
The top 100 of 151 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ABC-type transporter activity
45,533.32 100.00 31 31
leukotriene transport
26,561.10 34.15 14 24
ABC-type glutathione S-conjugate transporter activity
24,517.94 32.56 14 26
cyclic nucleotide transport
39,028.56 18.75 6 7
ABC-type xenobiotic transporter activity
8,884.55 16.49 16 82
heme transmembrane transport
14,487.88 15.22 7 22
ATPase-coupled inorganic anion transmembrane transporter activity
20,696.97 13.51 5 11
porphyrin-containing compound metabolic process
15,177.77 12.20 5 15
tetrapyrrole metabolic process
20,237.03 11.11 4 9
glutathione transmembrane transporter activity
6,374.67 9.46 7 50
Totals 362 13367

Change Log

Timestamp Action Category Detail
2023-04-02 Added XREF Reactome:R-HSA-429157
2023-04-02 Deleted XREF Reactome:R-HSA-5683325
2023-04-02 Deleted XREF Reactome:R-HSA-5223313
2023-04-02 Added XREF Reactome:R-HSA-9750656
2021-04-24 Deleted XREF EC:7.2.2.-
2021-04-22 Added XREF EC:7.2.2.-
2020-12-11 Deleted DEFINITION Primary transporter characterized by two nucleotide-binding domains and two transmembrane domains. Catalyzes the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
2020-12-11 Added SYNONYM ABC-type transmembrane transporter activity
2020-12-11 Added DEFINITION Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
2020-12-11 Updated TERM ABC-type transporter activity
Timestamp Action Category Detail
2020-12-11 Updated TERM ABC-type transporter activity
2019-06-29 Added TERM ABC-type transmembrane transporter activity
Timestamp Action Category Detail
2020-12-11 Deleted DEFINITION Primary transporter characterized by two nucleotide-binding domains and two transmembrane domains. Catalyzes the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
2020-12-11 Added SYNONYM ABC-type transmembrane transporter activity
2020-12-11 Added DEFINITION Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
2019-06-29 Added DEFINITION Primary transporter characterized by two nucleotide-binding domains and two transmembrane domains. Catalyzes the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
2019-06-29 Added SYNONYM ABC-type uptake permease activity
2019-06-29 Added SYNONYM ABC-type efflux permease activity
2019-06-29 Added SYNONYM ATP binding cassette transporter
2019-06-29 Added SYNONYM ABC-type efflux porter activity
2019-06-29 Added SYNONYM ATP-binding cassette transporter
2019-06-29 Added SYNONYM ABC transporter
2019-06-29 Added SYNONYM ATP-binding cassette (ABC) transporter activity
Timestamp Action Category Detail
2019-06-29 Added RELATION is a GO:0042626 (ATPase-coupled transmembrane transporter activity)
Timestamp Action Category Detail
2023-04-02 Added XREF Reactome:R-HSA-429157
2023-04-02 Deleted XREF Reactome:R-HSA-5683325
2023-04-02 Deleted XREF Reactome:R-HSA-5223313
2023-04-02 Added XREF Reactome:R-HSA-9750656
2021-04-24 Deleted XREF EC:7.2.2.-
2021-04-22 Added XREF EC:7.2.2.-
2020-07-19 Added XREF Reactome:R-HSA-266070
2020-07-19 Added XREF Reactome:R-HSA-5683325
2020-07-19 Added XREF Reactome:R-HSA-5387389
2020-07-19 Added XREF Reactome:R-HSA-9661405
2020-07-19 Added XREF Reactome:R-HSA-5223313
2020-07-19 Added XREF Reactome:R-HSA-5362459
2020-04-06 Added XREF Wikipedia:ATP-binding_cassette_transporter
2019-06-29 Added XREF TC:3.A.1
Timestamp Action Category Detail
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