GO:0140359
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ABC-type transporter activity
Molecular Function
Definition (GO:0140359 GONUTS page)
Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. PMID:26517899
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
ABC-type transmembrane transporter activity | exact |
ABC-type efflux porter activity | exact |
ATP binding cassette transporter | exact |
ATP-binding cassette transporter | exact |
ABC transporter | exact |
ABC-type uptake permease activity | exact |
ATP-binding cassette (ABC) transporter activity | exact |
ABC-type efflux permease activity | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0140359
Child Term | Relationship to GO:0140359 |
---|---|
ABC-type phytochelatin transporter activity
|
is_a |
ABC-type glycerol-3-phosphate transporter activity
|
is_a |
ABC-type thiosulfate transporter activity
|
is_a |
ABC-type azole transporter activity
|
is_a |
ABC-type cadmium transporter activity
|
is_a |
ABC-type molybdate transporter activity
|
is_a |
ABC-type bile acid transporter activity
|
is_a |
ABC-type indole transporter activity
|
is_a |
ABC-type glutathione S-conjugate transporter activity
|
is_a |
ABC-type zinc transporter activity
|
is_a |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000412 | ABC-2 transporter |
InterPro | IPR005951 | Retinal-specific ATP-binding cassette transporter |
InterPro | IPR011527 | ABC transporter type 1, transmembrane domain |
InterPro | IPR011868 | Molybdate ABC transporter, ATP-binding protein |
InterPro | IPR013525 | ABC-2 type transporter, transmembrane domain |
InterPro | IPR014216 | ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD |
InterPro | IPR015855 | ABC transporter, maltose/maltodextrin import, MalK-like |
InterPro | IPR015860 | ABC transporter, teichoic acids export TagH-like |
InterPro | IPR026082 | ABC transporter A |
InterPro | IPR032688 | ABC-2 type transporter permease protein NosY/YtrC-like |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0140359 based on ALL annotations
The top 100 of 2,893 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ABC-type transporter activity
|
192.48 | 100.00 | 1,012,776 | 1,012,776 |
ABC-type oligopeptide transporter activity
|
179.76 | 24.84 | 256,043 | 274,157 |
oligopeptide transmembrane transport
|
153.00 | 19.32 | 205,937 | 259,080 |
ATPase-coupled transmembrane transporter activity
|
123.19 | 17.11 | 191,772 | 299,632 |
lipid transport
|
81.56 | 11.46 | 137,454 | 324,372 |
ATPase-coupled lipid transmembrane transporter activity
|
178.62 | 10.35 | 105,663 | 113,861 |
ATP hydrolysis activity
|
20.71 | 10.25 | 692,274 | 6,435,441 |
transmembrane transport
|
18.84 | 9.78 | 1,000,978 | 10,224,532 |
ATP-binding cassette (ABC) transporter complex
|
31.75 | 9.15 | 172,757 | 1,047,404 |
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
|
90.86 | 6.27 | 68,308 | 144,701 |
Totals | 6827585 | 156922965 |
No co-occurrence statistics for GO:0140359 based on MANUAL annotations
The top 100 of 138 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ABC-type transporter activity
|
47,844.41 | 100.00 | 27 | 27 |
leukotriene transport
|
27,909.24 | 37.84 | 14 | 24 |
ABC-type glutathione S-conjugate transporter activity
|
25,762.37 | 35.90 | 14 | 26 |
cyclic nucleotide transport
|
41,009.49 | 21.43 | 6 | 7 |
ABC-type xenobiotic transporter activity
|
9,690.01 | 17.78 | 16 | 79 |
heme transmembrane transport
|
15,223.22 | 16.67 | 7 | 22 |
ATPase-coupled inorganic anion transmembrane transporter activity
|
21,747.46 | 15.15 | 5 | 11 |
porphyrin-containing compound metabolic process
|
15,948.14 | 13.51 | 5 | 15 |
tetrapyrrole metabolic process
|
21,264.18 | 12.50 | 4 | 9 |
glutathione transmembrane transport
|
8,201.90 | 10.71 | 6 | 35 |
Totals | 369 | 24384 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-04-02 | Deleted | XREF | Reactome:R-HSA-5683325 |
2023-04-02 | Added | XREF | Reactome:R-HSA-429157 |
2023-04-02 | Deleted | XREF | Reactome:R-HSA-5223313 |
2023-04-02 | Added | XREF | Reactome:R-HSA-9750656 |
2021-04-24 | Deleted | XREF | EC:7.2.2.- |
2021-04-22 | Added | XREF | EC:7.2.2.- |
2020-12-11 | Updated | TERM | ABC-type transporter activity |
2020-12-11 | Added | DEFINITION | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. |
2020-12-11 | Deleted | DEFINITION | Primary transporter characterized by two nucleotide-binding domains and two transmembrane domains. Catalyzes the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane. |
2020-12-11 | Added | SYNONYM | ABC-type transmembrane transporter activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-12-11 | Updated | TERM | ABC-type transporter activity |
2019-06-29 | Added | TERM | ABC-type transmembrane transporter activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-12-11 | Added | DEFINITION | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. |
2020-12-11 | Deleted | DEFINITION | Primary transporter characterized by two nucleotide-binding domains and two transmembrane domains. Catalyzes the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane. |
2020-12-11 | Added | SYNONYM | ABC-type transmembrane transporter activity |
2019-06-29 | Added | DEFINITION | Primary transporter characterized by two nucleotide-binding domains and two transmembrane domains. Catalyzes the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane. |
2019-06-29 | Added | SYNONYM | ABC-type efflux porter activity |
2019-06-29 | Added | SYNONYM | ATP binding cassette transporter |
2019-06-29 | Added | SYNONYM | ABC-type efflux permease activity |
2019-06-29 | Added | SYNONYM | ABC-type uptake permease activity |
2019-06-29 | Added | SYNONYM | ATP-binding cassette (ABC) transporter activity |
2019-06-29 | Added | SYNONYM | ABC transporter |
2019-06-29 | Added | SYNONYM | ATP-binding cassette transporter |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-06-29 | Added | RELATION | is a GO:0042626 (ATPase-coupled transmembrane transporter activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-04-02 | Deleted | XREF | Reactome:R-HSA-5683325 |
2023-04-02 | Added | XREF | Reactome:R-HSA-429157 |
2023-04-02 | Deleted | XREF | Reactome:R-HSA-5223313 |
2023-04-02 | Added | XREF | Reactome:R-HSA-9750656 |
2021-04-24 | Deleted | XREF | EC:7.2.2.- |
2021-04-22 | Added | XREF | EC:7.2.2.- |
2020-07-19 | Added | XREF | Reactome:R-HSA-5387389 |
2020-07-19 | Added | XREF | Reactome:R-HSA-5223313 |
2020-07-19 | Added | XREF | Reactome:R-HSA-266070 |
2020-07-19 | Added | XREF | Reactome:R-HSA-5683325 |
2020-07-19 | Added | XREF | Reactome:R-HSA-5362459 |
2020-07-19 | Added | XREF | Reactome:R-HSA-9661405 |
2020-04-06 | Added | XREF | Wikipedia:ATP-binding_cassette_transporter |
2019-06-29 | Added | XREF | TC:3.A.1 |
Timestamp | Action | Category | Detail |
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