Drosophila H2AV corresponds to histone H2AZ.
GO:0140849
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ATP-dependent H2AZ histone chaperone activity
Molecular Function
Definition (GO:0140849 GONUTS page)
A histone chaperone that mediates the exchange of histone H2A-H2B dimer and histone H2AZ-H2B dimers in a nucleosome, driven by ATP hydrolysis. Some chaperones insert H2AZ-H2B dimers and remove H2A-H2B, while others do the opposite. PMID:21241891 PMID:23580526 PMID:30309918
Comments
Drosophila H2AV corresponds to histone H2AZ.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
H2AZ histone exchange activity | related |
ATP-dependent H2A.Z histone chaperone activity | exact |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR008895 | Vps72/YL1 family |
InterPro | IPR037651 | SWR1-complex protein 3 |
RHEA | 13065 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:15377 | water |
has_participant | CHEBI | CHEBI:30616 | ATP(4-) |
has_participant | CHEBI | CHEBI:456216 | ADP(3-) |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:43474 | hydrogenphosphate |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0140849 based on ALL annotations
The top 100 of 2,858 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ATP-dependent H2AZ histone chaperone activity
|
781.50 | 100.00 | 249,443 | 249,443 |
chromatin extrusion motor activity
|
781.50 | 99.46 | 248,104 | 248,104 |
ATP-dependent H3-H4 histone complex chaperone activity
|
781.48 | 99.46 | 248,104 | 248,109 |
cohesin loader activity
|
780.85 | 99.38 | 248,104 | 248,310 |
chromatin looping
|
780.03 | 99.28 | 248,104 | 248,570 |
DNA clamp loader activity
|
676.79 | 86.20 | 248,104 | 286,489 |
single-stranded 3'-5' DNA helicase activity
|
327.04 | 34.93 | 169,342 | 404,658 |
forked DNA-dependent helicase activity
|
326.64 | 34.90 | 169,338 | 405,142 |
double-stranded DNA helicase activity
|
326.52 | 34.89 | 169,346 | 405,312 |
four-way junction helicase activity
|
276.28 | 30.29 | 169,346 | 479,025 |
Totals | 5140015 | 112655012 |
No co-occurrence statistics for GO:0140849 based on MANUAL annotations
The top 9 of 9 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ATP-dependent H2AZ histone chaperone activity
|
1,291,799.00 | 100.00 | 1 | 1 |
transcription initiation-coupled chromatin remodeling
|
2,826.69 | 0.22 | 1 | 457 |
Swr1 complex
|
1,656.15 | 0.13 | 1 | 780 |
histone binding
|
229.82 | 0.02 | 1 | 5,621 |
ATP binding
|
198.46 | 0.02 | 1 | 6,509 |
chromatin remodeling
|
196.65 | 0.02 | 1 | 6,569 |
ATP hydrolysis activity
|
127.42 | 0.01 | 1 | 10,138 |
DNA binding
|
106.50 | 0.01 | 1 | 12,130 |
nucleus
|
6.72 | 0.00 | 1 | 192,276 |
Totals | 9 | 234481 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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- Other
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-08-16 | Added | XREF | RHEA:13065 |
2023-01-16 | Added | DEFINITION | A histone chaperone that mediates the exchange of histone H2A-H2B dimer and histone H2AZ-H2B dimers in a nucleosome, driven by ATP hydrolysis. Some chaperones insert H2AZ-H2B dimers and remove H2A-H2B, while others do the opposite. |
2023-01-16 | Deleted | DEFINITION | A histone chaperone that mediates the exchange of histone H2A-H2B dimer and histone H2AZ-H2B dimers in a nucleosome, driven by ATP hydrolysis. Some chaperones insert H2AZ-H2B dimers dimers and remove H2A-H2B, while others do the opposite. |
2022-07-18 | Deleted | DEFINITION | A histone chaperone that unloads histone H2A-H2B dimer and deposits a variant histone H2AZ-H2B dimer instead into a nucleosome, driven by ATP hydrolysis. |
2022-07-18 | Added | DEFINITION | A histone chaperone that mediates the exchange of histone H2A-H2B dimer and histone H2AZ-H2B dimers in a nucleosome, driven by ATP hydrolysis. Some chaperones insert H2AZ-H2B dimers dimers and remove H2A-H2B, while others do the opposite. |
2022-06-12 | Added | TERM | ATP-dependent H2AZ histone chaperone activity |
2022-06-12 | Added | SYNONYM | ATP-dependent H2A.Z histone chaperone activity |
2022-06-12 | Added | RELATION | is a GO:0140674 (ATP-dependent histone chaperone activity) |
2022-06-12 | Added | DEFINITION | A histone chaperone that unloads histone H2A-H2B dimer and deposits a variant histone H2AZ-H2B dimer instead into a nucleosome, driven by ATP hydrolysis. |
2022-06-12 | Added | SYNONYM | H2AZ histone exchange activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-06-12 | Added | TERM | ATP-dependent H2AZ histone chaperone activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-01-16 | Added | DEFINITION | A histone chaperone that mediates the exchange of histone H2A-H2B dimer and histone H2AZ-H2B dimers in a nucleosome, driven by ATP hydrolysis. Some chaperones insert H2AZ-H2B dimers and remove H2A-H2B, while others do the opposite. |
2023-01-16 | Deleted | DEFINITION | A histone chaperone that mediates the exchange of histone H2A-H2B dimer and histone H2AZ-H2B dimers in a nucleosome, driven by ATP hydrolysis. Some chaperones insert H2AZ-H2B dimers dimers and remove H2A-H2B, while others do the opposite. |
2022-07-18 | Deleted | DEFINITION | A histone chaperone that unloads histone H2A-H2B dimer and deposits a variant histone H2AZ-H2B dimer instead into a nucleosome, driven by ATP hydrolysis. |
2022-07-18 | Added | DEFINITION | A histone chaperone that mediates the exchange of histone H2A-H2B dimer and histone H2AZ-H2B dimers in a nucleosome, driven by ATP hydrolysis. Some chaperones insert H2AZ-H2B dimers dimers and remove H2A-H2B, while others do the opposite. |
2022-06-12 | Added | SYNONYM | ATP-dependent H2A.Z histone chaperone activity |
2022-06-12 | Added | DEFINITION | A histone chaperone that unloads histone H2A-H2B dimer and deposits a variant histone H2AZ-H2B dimer instead into a nucleosome, driven by ATP hydrolysis. |
2022-06-12 | Added | SYNONYM | H2AZ histone exchange activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-06-12 | Added | RELATION | is a GO:0140674 (ATP-dependent histone chaperone activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-08-16 | Added | XREF | RHEA:13065 |
Timestamp | Action | Category | Detail |
---|
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