GO:0140948
JSON
histone H3K9 monomethyltransferase activity
Molecular Function
Definition (GO:0140948 GONUTS page)
Catalysis of the reaction: L-lysyl9-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl9-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
histone H3K9 monomethylase activity | exact |
histone H3K9 methylation | broad |
histone lysine N-monomethyltransferase activity (H3-K9 specific) | exact |
histone H3-K9 methylation | broad |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A0G2JWF0 | 10116 | A0A0G2JWF0_RAT | GO:0140938 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5YBY9 | 10116 | A0A8I5YBY9_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5ZVR7 | 10116 | A0A8I5ZVR7_RAT | GO:0140938 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A251 | 10116 | A0A8I6A251_RAT | GO:0140938 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6AGH5 | 10116 | A0A8I6AGH5_RAT | GO:0008168 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6ASP1 | 10116 | A0A8I6ASP1_RAT | GO:0140938 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A2VDP2 | 9913 | PCMD1_BOVIN | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A6IBP2 | 10116 | A6IBP2_RAT | GO:0140938 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6IBP3 | 10116 | A6IBP3_RAT | GO:0140938 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.1.1.367 | |
RHEA | 60288 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:61961 | N(6),N(6),N(6)-trimethyl-L-lysine residue |
has_participant | CHEBI | CHEBI:57856 | S-adenosyl-L-homocysteine zwitterion |
has_participant | CHEBI | CHEBI:61976 | N(6),N(6)-dimethyl-L-lysine(1+) residue |
has_participant | CHEBI | CHEBI:59789 | S-adenosyl-L-methionine zwitterion |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0140948 based on ALL annotations
The top 100 of 165 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
histone H3K9 monomethyltransferase activity
|
7,219,955.00 | 100.00 | 27 | 27 |
histone H3K27 monomethyltransferase activity
|
4,813,303.50 | 25.81 | 8 | 12 |
histone H3K9 dimethyltransferase activity
|
3,039,981.00 | 21.05 | 8 | 19 |
histone H3K9me2 methyltransferase activity
|
1,620,806.10 | 16.92 | 11 | 49 |
histone H3K27 dimethyltransferase activity
|
577,596.40 | 6.72 | 8 | 100 |
histone H4 methyltransferase activity
|
173,452.38 | 2.27 | 8 | 333 |
uterine gland development
|
222,152.47 | 2.22 | 2 | 65 |
tarsal gland development
|
197,806.98 | 2.04 | 2 | 73 |
polytene chromosome interband
|
145,490.28 | 1.92 | 8 | 397 |
facultative heterochromatin formation
|
137,851.17 | 1.83 | 8 | 419 |
Totals | 377 | 796652 |
No co-occurrence statistics for GO:0140948 based on MANUAL annotations
The top 22 of 22 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
histone H3K9 monomethyltransferase activity
|
1,291,799.00 | 100.00 | 1 | 1 |
histone H3K27 monomethyltransferase activity
|
1,291,799.00 | 100.00 | 1 | 1 |
histone H3K9 dimethyltransferase activity
|
430,599.70 | 33.33 | 1 | 3 |
histone H3K27 dimethyltransferase activity
|
161,474.88 | 12.50 | 1 | 8 |
histone H3K27 trimethyltransferase activity
|
143,533.22 | 11.11 | 1 | 9 |
histone H3K9 trimethyltransferase activity
|
80,737.44 | 6.25 | 1 | 16 |
histone H4 methyltransferase activity
|
71,766.61 | 5.56 | 1 | 18 |
facultative heterochromatin formation
|
25,329.39 | 1.96 | 1 | 51 |
habituation
|
16,147.49 | 1.25 | 1 | 80 |
polytene chromosome interband
|
14,353.32 | 1.11 | 1 | 90 |
Totals | 22 | 226129 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2022-11-08 | Added | XREF | EC:2.1.1.367 |
2022-11-08 | Added | XREF | RHEA:60288 |
2022-11-08 | Added | RELATION | is a GO:0046974 (histone H3K9 methyltransferase activity) |
2022-11-08 | Added | TERM | histone H3K9 monomethyltransferase activity |
2022-11-08 | Added | DEFINITION | Catalysis of the reaction: L-lysyl9-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl9-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me. |
2022-11-08 | Added | SYNONYM | histone H3-K9 methylation |
2022-11-08 | Added | SYNONYM | histone H3K9 monomethylase activity |
2022-11-08 | Added | SYNONYM | histone H3K9 methylation |
2022-11-08 | Added | SYNONYM | histone lysine N-monomethyltransferase activity (H3-K9 specific) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-11-08 | Added | TERM | histone H3K9 monomethyltransferase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-11-08 | Added | DEFINITION | Catalysis of the reaction: L-lysyl9-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl9-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me. |
2022-11-08 | Added | SYNONYM | histone H3-K9 methylation |
2022-11-08 | Added | SYNONYM | histone H3K9 monomethylase activity |
2022-11-08 | Added | SYNONYM | histone H3K9 methylation |
2022-11-08 | Added | SYNONYM | histone lysine N-monomethyltransferase activity (H3-K9 specific) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-11-08 | Added | RELATION | is a GO:0046974 (histone H3K9 methyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-11-08 | Added | XREF | EC:2.1.1.367 |
2022-11-08 | Added | XREF | RHEA:60288 |
Timestamp | Action | Category | Detail |
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