GO:0141201
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pyroptotic cell death
Biological Process
Definition (GO:0141201 GONUTS page)
A inflammatory cell death process associated with the generation of pyrogenic mediators that result from the activation of gasdermins. PMID:18846107 PMID:21760595 PMID:33883744
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
pyroptosis | broad |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0141201
Child Term | Relationship to GO:0141201 |
---|---|
cytotoxic T cell pyroptotic cell death
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating cell death and apoptosis using the new guidelines | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0141201 | pyroptotic cell death | Only in Taxon | 7742 | Vertebrata |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | Q8TAX9-2 | 9606 | GSDMB_HUMAN | GO:0070269 | 3 NOT-qualified manual annotations exist with evidence code ECO:0000314 from these references: PMID:36899106, PMID:36991122, PMID:36991125 | |
NOT-qualified manual | protein | Q8TAX9-3 | 9606 | GSDMB_HUMAN | GO:0070269 | 3 NOT-qualified manual annotations exist with evidence code ECO:0000314 from these references: PMID:36899106, PMID:36991122, PMID:36991125 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0141201 based on ALL annotations
The top 100 of 109 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pyroptotic cell death
|
752,659.40 | 100.00 | 259 | 259 |
positive regulation of immune response to tumor cell
|
419,094.44 | 29.08 | 98 | 176 |
membrane destabilizing activity
|
320,987.10 | 23.14 | 87 | 204 |
programmed necrotic cell death
|
116,931.02 | 11.89 | 87 | 560 |
cell adhesion mediator activity
|
93,145.62 | 9.94 | 87 | 703 |
leukocyte chemotaxis involved in inflammatory response
|
82,159.81 | 8.98 | 87 | 797 |
cardiolipin binding
|
52,575.47 | 6.66 | 152 | 2,176 |
pyroptotic inflammatory response
|
48,513.44 | 6.25 | 173 | 2,684 |
cytolysis
|
28,445.42 | 3.52 | 87 | 2,302 |
non-canonical inflammasome complex
|
218,514.02 | 3.20 | 9 | 31 |
Totals | 4876 | 129564824 |
No co-occurrence statistics for GO:0141201 based on MANUAL annotations
The top 80 of 80 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pyroptotic cell death
|
86,119.94 | 100.00 | 15 | 15 |
ferroptosis
|
64,589.95 | 18.75 | 3 | 4 |
positive regulation of immune response to tumor cell
|
13,456.24 | 11.90 | 5 | 32 |
pericyte cell migration
|
28,706.65 | 10.53 | 2 | 6 |
membrane destabilizing activity
|
14,353.32 | 10.00 | 3 | 18 |
cytolysis
|
13,597.88 | 9.68 | 3 | 19 |
wide pore channel activity
|
8,611.99 | 9.65 | 11 | 110 |
positive regulation of osteoclast development
|
14,353.32 | 8.00 | 2 | 12 |
cardiolipin binding
|
6,273.64 | 7.10 | 11 | 151 |
leukocyte chemotaxis involved in inflammatory response
|
7,829.08 | 6.67 | 3 | 33 |
Totals | 324 | 675060 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7742 (Vertebrata) |
2024-05-01 | Added | RELATION | is a GO:0070269 (pyroptotic inflammatory response) |
2024-05-01 | Added | RELATION | is a GO:0012501 (programmed cell death) |
2024-05-01 | Added | SYNONYM | pyroptosis |
2024-05-01 | Added | TERM | pyroptotic cell death |
2024-05-01 | Added | DEFINITION | A inflammatory cell death process associated with the generation of pyrogenic mediators that result from the activation of gasdermins. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-05-01 | Added | TERM | pyroptotic cell death |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-05-01 | Added | SYNONYM | pyroptosis |
2024-05-01 | Added | DEFINITION | A inflammatory cell death process associated with the generation of pyrogenic mediators that result from the activation of gasdermins. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-05-01 | Added | RELATION | is a GO:0070269 (pyroptotic inflammatory response) |
2024-05-01 | Added | RELATION | is a GO:0012501 (programmed cell death) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7742 (Vertebrata) |
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