This term is obsolete.

GO:0141201 JSON

pyroptotic cell death

Biological Process

Definition (GO:0141201 GONUTS page)

A inflammatory cell death process associated with the generation of pyrogenic mediators that result from the activation of gasdermins. PMID:18846107 PMID:21760595 PMID:33883744

381 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
pyroptosis broad

Ancestor Chart

Ancestor chart for GO:0141201
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0141201

Child Term Relationship to
GO:0141201
cytotoxic T cell pyroptotic cell death
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating cell death and apoptosis using the new guidelines Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0141201 pyroptotic cell death Only in Taxon 7742 Vertebrata

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein Q8TAX9-2 9606 GSDMB_HUMAN GO:0070269 3 NOT-qualified manual annotations exist with evidence code ECO:0000314 from these references: PMID:36899106, PMID:36991122, PMID:36991125
NOT-qualified manual protein Q8TAX9-3 9606 GSDMB_HUMAN GO:0070269 3 NOT-qualified manual annotations exist with evidence code ECO:0000314 from these references: PMID:36899106, PMID:36991122, PMID:36991125

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0141201 based on ALL annotations
The top 100 of 109 co-occurring terms
Co-occurring Term PR S% #Together #Compared
pyroptotic cell death
752,659.40 100.00 259 259
positive regulation of immune response to tumor cell
419,094.44 29.08 98 176
membrane destabilizing activity
320,987.10 23.14 87 204
programmed necrotic cell death
116,931.02 11.89 87 560
cell adhesion mediator activity
93,145.62 9.94 87 703
leukocyte chemotaxis involved in inflammatory response
82,159.81 8.98 87 797
cardiolipin binding
52,575.47 6.66 152 2,176
pyroptotic inflammatory response
48,513.44 6.25 173 2,684
cytolysis
28,445.42 3.52 87 2,302
non-canonical inflammasome complex
218,514.02 3.20 9 31
Totals 4876 129564824
No co-occurrence statistics for GO:0141201 based on MANUAL annotations
The top 80 of 80 co-occurring terms
Co-occurring Term PR S% #Together #Compared
pyroptotic cell death
86,119.94 100.00 15 15
ferroptosis
64,589.95 18.75 3 4
positive regulation of immune response to tumor cell
13,456.24 11.90 5 32
pericyte cell migration
28,706.65 10.53 2 6
membrane destabilizing activity
14,353.32 10.00 3 18
cytolysis
13,597.88 9.68 3 19
wide pore channel activity
8,611.99 9.65 11 110
positive regulation of osteoclast development
14,353.32 8.00 2 12
cardiolipin binding
6,273.64 7.10 11 151
leukocyte chemotaxis involved in inflammatory response
7,829.08 6.67 3 33
Totals 324 675060

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2024-05-01 Added RELATION is a GO:0070269 (pyroptotic inflammatory response)
2024-05-01 Added RELATION is a GO:0012501 (programmed cell death)
2024-05-01 Added SYNONYM pyroptosis
2024-05-01 Added TERM pyroptotic cell death
2024-05-01 Added DEFINITION A inflammatory cell death process associated with the generation of pyrogenic mediators that result from the activation of gasdermins.
Timestamp Action Category Detail
2024-05-01 Added TERM pyroptotic cell death
Timestamp Action Category Detail
2024-05-01 Added SYNONYM pyroptosis
2024-05-01 Added DEFINITION A inflammatory cell death process associated with the generation of pyrogenic mediators that result from the activation of gasdermins.
Timestamp Action Category Detail
2024-05-01 Added RELATION is a GO:0070269 (pyroptotic inflammatory response)
2024-05-01 Added RELATION is a GO:0012501 (programmed cell death)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
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