This term is obsolete.

GO:0160216 JSON

protein lysine delactylase activity

Molecular Function

Definition (GO:0160216 GONUTS page)

Catalysis of the reaction: H2O + N6-lactoyl-L-lysyl-[protein] = (S)-lactate + L-lysyl-[protein]. PMID:35044827

302 annotations

Ancestor Chart

Ancestor chart for GO:0160216
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
RHEA 81387

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:231527 N(6)-[(S)-lactoyl]-L-lysine residue
has_participant CHEBI CHEBI:29969 L-lysinium residue
has_participant CHEBI CHEBI:15377 water
has_participant CHEBI CHEBI:16651 (S)-lactate

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0160216 based on ALL annotations
The top 100 of 190 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein lysine delactylase activity
676,296.44 100.00 293 293
histone decrotonylase activity
521,051.62 76.84 292 379
protein de-2-hydroxyisobutyrylase activity
676,296.44 68.26 200 200
fungiform papilla formation
349,419.84 24.47 93 180
Krueppel-associated box domain binding
355,538.72 24.47 92 175
protein decrotonylase activity
188,404.64 23.35 173 621
hair follicle placode formation
204,938.33 15.42 70 231
protein lysine deacetylase activity
81,344.36 12.03 293 2,436
negative regulation of cardiac muscle cell differentiation
93,594.60 10.67 93 672
negative regulation of transcription by competitive promoter binding
89,798.70 10.43 96 723
Totals 10251 1137288
No co-occurrence statistics for GO:0160216 based on MANUAL annotations
The top 100 of 179 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein lysine delactylase activity
64,160.59 100.00 22 22
histone decrotonylase activity
44,912.41 67.74 21 30
protein de-2-hydroxyisobutyrylase activity
64,160.59 63.64 14 14
fungiform papilla formation
48,120.44 36.00 9 12
protein decrotonylase activity
64,160.59 31.82 7 7
Krueppel-associated box domain binding
44,912.41 28.00 7 10
hair follicle placode formation
27,497.40 26.47 9 21
protein lysine deacetylase activity
14,418.11 21.98 20 89
histone H4K16 deacetylase activity, hydrolytic mechanism
20,050.19 15.15 5 16
positive regulation of male mating behavior
28,515.82 14.81 4 9
Totals 583 23512

Change Log

Timestamp Action Category Detail
2024-12-11 Added XREF RHEA:81387
2024-09-20 Added RELATION is a GO:0140096 (catalytic activity, acting on a protein)
2024-09-18 Added RELATION is a GO:0160215 (deacylase activity)
2024-09-18 Added DEFINITION Catalysis of the reaction: H2O + N6-lactoyl-L-lysyl-[protein] = (S)-lactate + L-lysyl-[protein].
2024-09-18 Added TERM protein lysine delactylase activity
Timestamp Action Category Detail
2024-09-18 Added TERM protein lysine delactylase activity
Timestamp Action Category Detail
2024-09-18 Added DEFINITION Catalysis of the reaction: H2O + N6-lactoyl-L-lysyl-[protein] = (S)-lactate + L-lysyl-[protein].
Timestamp Action Category Detail
2024-09-20 Added RELATION is a GO:0140096 (catalytic activity, acting on a protein)
2024-09-18 Added RELATION is a GO:0160215 (deacylase activity)
Timestamp Action Category Detail
2024-12-11 Added XREF RHEA:81387
Timestamp Action Category Detail
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