This term is obsolete.

GO:1902254 JSON

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator

Biological Process

Definition (GO:1902254 GONUTS page)

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator. PMID:15705871

Acknowledgement

This term was created by the GO Consortium with support from: BHF image

2,547 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
down regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator exact
downregulation of signal transduction by p53 class mediator resulting in induction of apoptosis related
downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator exact
negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator exact
down-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator exact
inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis related
down-regulation of intrinsic apoptotic signaling pathway by p53 class mediator exact
negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis related
down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis related
down-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis related

Ancestor Chart

Ancestor chart for GO:1902254
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:1902254

Child Term Relationship to
GO:1902254
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
is_a
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating cell death and apoptosis using the new guidelines Link

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:

Ontology Development Project
signalling Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator Never in Taxon 4896 Schizosaccharomyces pombe

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A0G2KB20 10116 A0A0G2KB20_RAT GO:0042981 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5ZMQ2 10116 A0A8I5ZMQ2_RAT GO:0042981 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AE08 10116 A0A8I6AE08_RAT GO:0042981 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6J853 10116 A6J853_RAT GO:0042981 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZZ22 10116 D3ZZ22_RAT GO:0042981 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q28ER3 8364 BIR52_XENTR GO:0043066 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q28H51 8364 BIR51_XENTR GO:0043066 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q4R1J6 8355 BI51B_XENLA GO:0043066 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q50L39 8355 BI52A_XENLA GO:0043066 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15853809
NOT-qualified manual protein Q564A4 7955 Q564A4_DANRE GO:0043066 1 NOT-qualified manual annotation exists with evidence code ECO:0000316 from this reference: PMID:16888646

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:1902254 based on ALL annotations
The top 100 of 480 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
288,370.97 100.00 676 676
deoxyribonucleoside triphosphate metabolic process
270,158.06 13.05 89 95
positive regulation of neurotransmitter uptake
288,370.97 10.36 70 70
negative regulation of intralumenal vesicle formation
284,309.40 10.34 70 71
negative regulation of spontaneous neurotransmitter secretion
284,309.40 10.34 70 71
ribonucleoside diphosphate metabolic process
89,040.87 10.08 88 285
positive regulation of protein linear polyubiquitination
118,046.60 9.01 70 171
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway
123,328.48 8.87 68 159
positive regulation of G0 to G1 transition
57,544.88 8.62 89 446
cellular response to actinomycin D
104,715.72 8.23 65 179
Totals 7211 219611
No co-occurrence statistics for GO:1902254 based on MANUAL annotations
The top 100 of 453 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
36,908.54 100.00 35 35
cellular response to actinomycin D
20,131.93 15.00 6 11
deoxyribonucleoside triphosphate metabolic process
30,757.12 13.89 5 6
response to formaldehyde
26,363.24 13.51 5 7
cellular response to vitamin B1
26,363.24 13.51 5 7
atrial septum development
8,334.19 11.86 7 31
response to water-immersion restraint stress
13,181.62 11.36 5 14
response to ether
13,181.62 11.36 5 14
NEDD8 ligase activity
9,227.14 11.32 6 24
regulation of protein catabolic process at postsynapse, modulating synaptic transmission
8,388.31 9.62 5 22
Totals 403 4738

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe)
2013-06-27 Added SYNONYM inhibition of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
2013-06-27 Added TERM negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
2013-06-27 Added SYNONYM inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis
2013-06-27 Added SYNONYM negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis
2013-06-27 Added SYNONYM down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis
2013-06-27 Added SYNONYM down-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis
2013-06-27 Added SYNONYM downregulation of intrinsic apoptotic signaling pathway by p53 class mediator
2013-06-27 Added SYNONYM downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
2013-06-27 Added SYNONYM negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
Timestamp Action Category Detail
2013-06-27 Added TERM negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
Timestamp Action Category Detail
2013-06-27 Added SYNONYM inhibition of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
2013-06-27 Added SYNONYM inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis
2013-06-27 Added SYNONYM negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis
2013-06-27 Added SYNONYM down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis
2013-06-27 Added SYNONYM down-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis
2013-06-27 Added SYNONYM downregulation of intrinsic apoptotic signaling pathway by p53 class mediator
2013-06-27 Added SYNONYM downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
2013-06-27 Added SYNONYM negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
2013-06-27 Added SYNONYM down regulation of intrinsic apoptotic signaling pathway by p53 class mediator
2013-06-27 Added SYNONYM down-regulation of intrinsic apoptotic signaling pathway by p53 class mediator
2013-06-27 Added SYNONYM down regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
2013-06-27 Added SYNONYM downregulation of signal transduction by p53 class mediator resulting in induction of apoptosis
2013-06-27 Added SYNONYM inhibition of intrinsic apoptotic signaling pathway by p53 class mediator
2013-06-27 Added SYNONYM down-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
2013-06-27 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.
Timestamp Action Category Detail
2013-06-27 Added RELATION negatively regulates GO:0072332 (intrinsic apoptotic signaling pathway by p53 class mediator)
2013-06-27 Added RELATION is a GO:1901797 (negative regulation of signal transduction by p53 class mediator)
2013-06-27 Added RELATION is a GO:1902253 (regulation of intrinsic apoptotic signaling pathway by p53 class mediator)
2013-06-27 Added RELATION is a GO:2001243 (negative regulation of intrinsic apoptotic signaling pathway)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe)
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