GO:1902254
JSON
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
Biological Process
Definition (GO:1902254 GONUTS page)
Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator. PMID:15705871
Acknowledgement
This term was created by the GO Consortium with support from:
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
down regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator | exact |
downregulation of signal transduction by p53 class mediator resulting in induction of apoptosis | related |
downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator | exact |
negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator | exact |
down-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator | exact |
inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis | related |
down-regulation of intrinsic apoptotic signaling pathway by p53 class mediator | exact |
negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis | related |
down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis | related |
down-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:1902254
Child Term | Relationship to GO:1902254 |
---|---|
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
|
is_a |
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating cell death and apoptosis using the new guidelines | Link |
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
Ontology Development Project | |
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signalling | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:1902254 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator | Never in Taxon | 4896 | Schizosaccharomyces pombe |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A0G2KB20 | 10116 | A0A0G2KB20_RAT | GO:0042981 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5ZMQ2 | 10116 | A0A8I5ZMQ2_RAT | GO:0042981 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6AE08 | 10116 | A0A8I6AE08_RAT | GO:0042981 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6J853 | 10116 | A6J853_RAT | GO:0042981 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZZ22 | 10116 | D3ZZ22_RAT | GO:0042981 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q28ER3 | 8364 | BIR52_XENTR | GO:0043066 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q28H51 | 8364 | BIR51_XENTR | GO:0043066 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q4R1J6 | 8355 | BI51B_XENLA | GO:0043066 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q50L39 | 8355 | BI52A_XENLA | GO:0043066 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15853809 | |
NOT-qualified manual | protein | Q564A4 | 7955 | Q564A4_DANRE | GO:0043066 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000316 from this reference: PMID:16888646 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:1902254 based on ALL annotations
The top 100 of 480 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
|
288,370.97 | 100.00 | 676 | 676 |
deoxyribonucleoside triphosphate metabolic process
|
270,158.06 | 13.05 | 89 | 95 |
positive regulation of neurotransmitter uptake
|
288,370.97 | 10.36 | 70 | 70 |
negative regulation of intralumenal vesicle formation
|
284,309.40 | 10.34 | 70 | 71 |
negative regulation of spontaneous neurotransmitter secretion
|
284,309.40 | 10.34 | 70 | 71 |
ribonucleoside diphosphate metabolic process
|
89,040.87 | 10.08 | 88 | 285 |
positive regulation of protein linear polyubiquitination
|
118,046.60 | 9.01 | 70 | 171 |
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway
|
123,328.48 | 8.87 | 68 | 159 |
positive regulation of G0 to G1 transition
|
57,544.88 | 8.62 | 89 | 446 |
cellular response to actinomycin D
|
104,715.72 | 8.23 | 65 | 179 |
Totals | 7211 | 219611 |
No co-occurrence statistics for GO:1902254 based on MANUAL annotations
The top 100 of 453 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
|
36,908.54 | 100.00 | 35 | 35 |
cellular response to actinomycin D
|
20,131.93 | 15.00 | 6 | 11 |
deoxyribonucleoside triphosphate metabolic process
|
30,757.12 | 13.89 | 5 | 6 |
response to formaldehyde
|
26,363.24 | 13.51 | 5 | 7 |
cellular response to vitamin B1
|
26,363.24 | 13.51 | 5 | 7 |
atrial septum development
|
8,334.19 | 11.86 | 7 | 31 |
response to water-immersion restraint stress
|
13,181.62 | 11.36 | 5 | 14 |
response to ether
|
13,181.62 | 11.36 | 5 | 14 |
NEDD8 ligase activity
|
9,227.14 | 11.32 | 6 | 24 |
regulation of protein catabolic process at postsynapse, modulating synaptic transmission
|
8,388.31 | 9.62 | 5 | 22 |
Totals | 403 | 4738 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe) |
2013-06-27 | Added | SYNONYM | inhibition of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator |
2013-06-27 | Added | TERM | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator |
2013-06-27 | Added | SYNONYM | inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis |
2013-06-27 | Added | SYNONYM | negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis |
2013-06-27 | Added | SYNONYM | down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis |
2013-06-27 | Added | SYNONYM | down-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis |
2013-06-27 | Added | SYNONYM | downregulation of intrinsic apoptotic signaling pathway by p53 class mediator |
2013-06-27 | Added | SYNONYM | downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator |
2013-06-27 | Added | SYNONYM | negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-06-27 | Added | TERM | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-06-27 | Added | SYNONYM | inhibition of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator |
2013-06-27 | Added | SYNONYM | inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis |
2013-06-27 | Added | SYNONYM | negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis |
2013-06-27 | Added | SYNONYM | down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis |
2013-06-27 | Added | SYNONYM | down-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis |
2013-06-27 | Added | SYNONYM | downregulation of intrinsic apoptotic signaling pathway by p53 class mediator |
2013-06-27 | Added | SYNONYM | downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator |
2013-06-27 | Added | SYNONYM | negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator |
2013-06-27 | Added | SYNONYM | down regulation of intrinsic apoptotic signaling pathway by p53 class mediator |
2013-06-27 | Added | SYNONYM | down-regulation of intrinsic apoptotic signaling pathway by p53 class mediator |
2013-06-27 | Added | SYNONYM | down regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator |
2013-06-27 | Added | SYNONYM | downregulation of signal transduction by p53 class mediator resulting in induction of apoptosis |
2013-06-27 | Added | SYNONYM | inhibition of intrinsic apoptotic signaling pathway by p53 class mediator |
2013-06-27 | Added | SYNONYM | down-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator |
2013-06-27 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-06-27 | Added | RELATION | negatively regulates GO:0072332 (intrinsic apoptotic signaling pathway by p53 class mediator) |
2013-06-27 | Added | RELATION | is a GO:1901797 (negative regulation of signal transduction by p53 class mediator) |
2013-06-27 | Added | RELATION | is a GO:1902253 (regulation of intrinsic apoptotic signaling pathway by p53 class mediator) |
2013-06-27 | Added | RELATION | is a GO:2001243 (negative regulation of intrinsic apoptotic signaling pathway) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe) |
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