This term is obsolete.

GO:1990140 JSON

molybdopterin synthase complex

Cellular Component

Definition (GO:1990140 GONUTS page)

A heterotetrameric protein complex that catalyses sulfur transfer from the sulfur carrier subunit of molybdopterin synthase to precursor Z to synthesize molybdopterin as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved. PMID:11135669 PMID:16669776

4,331 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
molybdopterin cofactor (Moco) biosynthesis sulfurtransferase complex related
molybdopterin converting factor complex exact
MPT synthase complex exact

Ancestor Chart

Ancestor chart for GO:1990140
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Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:1990140 molybdopterin synthase complex Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A022PQZ0 4155 A0A022PQZ0_ERYGU GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A022PY49 4155 A0A022PY49_ERYGU GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A022QF08 4155 A0A022QF08_ERYGU GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A059B690 71139 A0A059B690_EUCGR GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A059B6X6 71139 A0A059B6X6_EUCGR GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A059B9U1 71139 A0A059B9U1_EUCGR GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A061E742 3641 A0A061E742_THECC GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A061ERE5 3641 A0A061ERE5_THECC GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A067EGP5 2711 A0A067EGP5_CITSI GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A078G8S0 3708 A0A078G8S0_BRANA GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
InterPro IPR028888 Molybdopterin synthase catalytic subunit, eukaryotes

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0019008 obsolete molybdopterin synthase complex replaced_by GO:1990140

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:1990140 based on ALL annotations
The top 100 of 149 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:1990140
molybdopterin synthase complex
46,449.81 100.00 4,266 4,266
GO:0030366
molybdopterin synthase activity
12,696.82 27.33 4,265 15,603
GO:1990133
molybdopterin adenylyltransferase complex
4,161.01 7.68 1,496 16,700
GO:0032324
molybdopterin cofactor biosynthetic process
1,793.40 3.77 2,571 66,590
GO:0006777
Mo-molybdopterin cofactor biosynthetic process
659.32 1.42 4,266 300,546
GO:0033934
glucan 1,4-alpha-maltotriohydrolase activity
123.69 0.13 11 4,131
GO:0000025
maltose catabolic process
119.07 0.13 11 4,291
GO:0140672
ATAC complex
112.27 0.12 11 4,551
GO:0005700
polytene chromosome
110.31 0.12 11 4,632
GO:0004574
oligo-1,6-glucosidase activity
88.60 0.11 11 5,767
Totals 30478 103631137
No co-occurrence statistics for GO:1990140 based on MANUAL annotations
The top 20 of 20 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:1990140
molybdopterin synthase complex
22,405.29 100.00 63 63
GO:0030366
molybdopterin synthase activity
21,543.54 76.92 50 52
GO:0006777
Mo-molybdopterin cofactor biosynthetic process
3,009.67 13.43 63 469
GO:1990133
molybdopterin adenylyltransferase complex
2,621.90 7.53 11 94
GO:0032324
molybdopterin cofactor biosynthetic process
3,136.74 6.60 7 50
GO:0050464
nitrate reductase (NADPH) activity
8,962.11 3.03 2 5
GO:0018315
molybdenum incorporation into molybdenum-molybdopterin complex
11,202.64 1.56 1 2
GO:0140672
ATAC complex
153.46 0.48 1 146
GO:0005700
polytene chromosome
78.89 0.29 1 284
GO:0009734
auxin-activated signaling pathway
56.29 0.22 1 398
Totals 260 373675

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_metagenomics 111

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2024-05-15 Deleted DEFINITION A heterotetrameric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.
2024-05-15 Added DEFINITION A heterotetrameric protein complex that catalyses sulfur transfer from the sulfur carrier subunit of molybdopterin synthase to precursor Z to synthesize molybdopterin as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.
2024-05-15 Added SYNONYM MPT synthase complex
2024-05-15 Deleted SYNONYM molybdopterin synthase complex
2024-05-15 Updated TERM molybdopterin synthase complex
2024-05-04 Added SYNONYM molybdopterin synthase complex
2024-05-04 Added SYNONYM molybdopterin converting factor complex
2024-05-04 Added SUBSET goslim_metagenomics
2024-05-04 Added DEFINITION A heterotetrameric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.
Timestamp Action Category Detail
2024-05-15 Updated TERM molybdopterin synthase complex
2013-07-13 Added TERM MPT synthase complex
Timestamp Action Category Detail
2024-05-15 Deleted DEFINITION A heterotetrameric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.
2024-05-15 Added DEFINITION A heterotetrameric protein complex that catalyses sulfur transfer from the sulfur carrier subunit of molybdopterin synthase to precursor Z to synthesize molybdopterin as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.
2024-05-15 Added SYNONYM MPT synthase complex
2024-05-15 Deleted SYNONYM molybdopterin synthase complex
2024-05-04 Added SYNONYM molybdopterin synthase complex
2024-05-04 Added SYNONYM molybdopterin converting factor complex
2024-05-04 Added DEFINITION A heterotetrameric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.
2024-05-04 Deleted DEFINITION A heterodimeric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.
2013-07-13 Added DEFINITION A heterodimeric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.
2013-07-13 Added SYNONYM molybdopterin cofactor (Moco) biosynthesis sulfurtransferase complex
Timestamp Action Category Detail
2024-04-26 Added RELATION capable of GO:0030366 (molybdopterin synthase activity)
2017-11-08 Deleted RELATION part of GO:0005829 (cytosol)
2017-05-22 Added RELATION part of GO:0005829 (cytosol)
2017-04-06 Deleted RELATION part of GO:0005829 (cytosol)
2013-11-28 Deleted RELATION is a GO:0044445 (obsolete cytosolic part)
2013-11-15 Added RELATION is a GO:1990228 (sulfurtransferase complex)
2013-11-15 Deleted RELATION is a GO:0043234 (protein complex)
2013-07-18 Added RELATION is a GO:0044445 (obsolete cytosolic part)
2013-07-14 Added RELATION part of GO:0005829 (cytosol)
2013-07-13 Added RELATION is a GO:0043234 (protein complex)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2024-05-04 Added SUBSET goslim_metagenomics
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