GO:1990147
JSON
talin binding
Molecular Function
Definition (GO:1990147 GONUTS page)
Binding to a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types. PMID:23372168
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P21333-1 | 9606 | FLNA_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
NOT-qualified manual | protein | P63026 | 9913 | VAMP2_BOVIN | GO:0005515 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699 | |
NOT-qualified manual | protein | Q86V48 | 9606 | LUZP1_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:1990147 based on ALL annotations
The top 20 of 20 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
talin binding
|
2,030,612.40 | 100.00 | 96 | 96 |
negative regulation of establishment of protein localization
|
1,989,171.10 | 97.96 | 96 | 98 |
positive regulation of establishment of protein localization
|
323,281.56 | 15.92 | 96 | 603 |
negative regulation of cell-substrate adhesion
|
191,680.22 | 9.44 | 96 | 1,017 |
regulation of cellular response to stress
|
176,415.19 | 8.69 | 96 | 1,105 |
regulation of glomerular filtration
|
110,254.02 | 5.41 | 91 | 1,676 |
vinculin binding
|
107,522.77 | 5.30 | 96 | 1,813 |
focal adhesion assembly
|
101,197.00 | 4.97 | 91 | 1,826 |
negative regulation of stress fiber assembly
|
31,964.32 | 1.57 | 91 | 5,781 |
regulation of actin cytoskeleton organization
|
7,823.53 | 0.39 | 96 | 24,917 |
Totals | 1140 | 79189448 |
No co-occurrence statistics for GO:1990147 based on MANUAL annotations
The top 18 of 18 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
talin binding
|
258,359.80 | 100.00 | 5 | 5 |
negative regulation of establishment of protein localization
|
215,299.84 | 83.33 | 5 | 6 |
positive regulation of establishment of protein localization
|
31,507.29 | 12.20 | 5 | 41 |
regulation of cellular response to stress
|
28,706.64 | 11.11 | 5 | 45 |
regulation of glomerular filtration
|
25,205.83 | 9.52 | 4 | 41 |
negative regulation of cell-substrate adhesion
|
16,561.53 | 6.41 | 5 | 78 |
focal adhesion assembly
|
7,598.82 | 2.92 | 4 | 136 |
vinculin binding
|
6,982.70 | 2.70 | 5 | 185 |
negative regulation of stress fiber assembly
|
5,245.88 | 2.02 | 4 | 197 |
regulation of actin cytoskeleton organization
|
741.99 | 0.29 | 5 | 1,741 |
Totals | 62 | 126566 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types. |
2021-05-24 | Added | DEFINITION | Binding to a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types. |
2013-07-28 | Added | TERM | talin binding |
2013-07-28 | Added | RELATION | is a GO:0008092 (cytoskeletal protein binding) |
2013-07-28 | Added | DEFINITION | Interacting selectively and non-covalently with a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-07-28 | Added | TERM | talin binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types. |
2021-05-24 | Added | DEFINITION | Binding to a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types. |
2013-07-28 | Added | DEFINITION | Interacting selectively and non-covalently with a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-07-28 | Added | RELATION | is a GO:0008092 (cytoskeletal protein binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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