An example of this is ATF1in human (P18846) in PMID:12871976 (inferred from physical interaction).
GO:1990590
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ATF1-ATF4 transcription factor complex
Cellular Component
Definition (GO:1990590 GONUTS page)
Transcription factor complex consisting of ATF1 and ATF4 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway. PMID:12871976
Comments
An example of this is ATF1in human (P18846) in PMID:12871976 (inferred from physical interaction).
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:1990590 | ATF1-ATF4 transcription factor complex | Only in Taxon | 2759 | Eukaryota |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2JW23 | 10116 | A0A0G2JW23_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2K8T1 | 10116 | A0A0G2K8T1_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1B0GR71 | 10090 | A0A1B0GR71_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1B0GRK6 | 10090 | A0A1B0GRK6_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1D8PHF8 | 237561 | A0A1D8PHF8_CANAL | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5Y8H4 | 10116 | A0A8I5Y8H4_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A0E5 | 10116 | A0A8I6A0E5_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:1990590 based on ALL annotations
The top 99 of 99 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ATF1-ATF4 transcription factor complex
|
182,698.02 | 100.00 | 1,067 | 1,067 |
ATF4-CREB1 transcription factor complex
|
33,735.23 | 18.45 | 1,061 | 5,746 |
L-asparagine metabolic process
|
182,698.03 | 9.00 | 96 | 96 |
positive regulation of sodium-dependent phosphate transport
|
97,873.94 | 7.86 | 90 | 168 |
Lewy body core
|
59,860.10 | 7.59 | 96 | 293 |
positive regulation of biomineral tissue development
|
44,082.63 | 6.67 | 90 | 373 |
integrated stress response signaling
|
34,497.89 | 6.59 | 98 | 519 |
HRI-mediated signaling
|
27,502.93 | 6.05 | 98 | 651 |
PERK-mediated unfolded protein response
|
26,485.81 | 5.96 | 98 | 676 |
positive regulation of vascular associated smooth muscle cell apoptotic process
|
29,102.34 | 5.84 | 90 | 565 |
Totals | 18504 | 179143204 |
No co-occurrence statistics for GO:1990590 based on MANUAL annotations
The top 91 of 91 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ATF1-ATF4 transcription factor complex
|
41,670.93 | 100.00 | 31 | 31 |
ATF4-CREB1 transcription factor complex
|
15,061.78 | 35.71 | 30 | 83 |
response to purine-containing compound
|
8,013.64 | 9.62 | 5 | 26 |
HRI-mediated signaling
|
6,721.12 | 8.77 | 5 | 31 |
PERK-mediated unfolded protein response
|
5,208.87 | 7.58 | 5 | 40 |
L-asparagine metabolic process
|
41,670.93 | 6.45 | 2 | 2 |
positive regulation of sodium-dependent phosphate transport
|
13,890.31 | 5.71 | 2 | 6 |
integrated stress response signaling
|
3,109.77 | 5.38 | 5 | 67 |
response to cobalt ion
|
3,401.71 | 5.26 | 4 | 49 |
Lewy body core
|
8,334.19 | 5.13 | 2 | 10 |
Totals | 480 | 827207 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2023-10-28 | Added | RELATION | capable of part of GO:0034976 (response to endoplasmic reticulum stress) |
2023-10-28 | Deleted | RELATION | capable of part of GO:1990440 (obsolete positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress) |
2021-05-04 | Deleted | XREF | IntAct:EBI-10043123 |
2021-05-04 | Deleted | XREF | IntAct:EBI-10043370 |
2020-11-03 | Deleted | RELATION | part of GO:0005634 (nucleus) |
2020-11-03 | Deleted | RELATION | capable of GO:0000977 (RNA polymerase II transcription regulatory region sequence-specific DNA binding) |
2020-04-25 | Added | RELATION | part of GO:0005634 (nucleus) |
2017-11-08 | Deleted | RELATION | part of GO:0005634 (nucleus) |
2017-10-07 | Added | XREF | IntAct:EBI-10043123 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-01-12 | Updated | TERM | ATF1-ATF4 transcription factor complex |
2014-12-20 | Added | TERM | ATF1-CREB1-ATF4 transcription factor complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-01-12 | Added | DEFINITION | Transcription factor complex consisting of ATF1 and ATF4 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway. |
2015-01-12 | Deleted | DEFINITION | Transcription factor complex that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway. |
2014-12-20 | Added | DEFINITION | Transcription factor complex that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-10-28 | Added | RELATION | capable of part of GO:0034976 (response to endoplasmic reticulum stress) |
2023-10-28 | Deleted | RELATION | capable of part of GO:1990440 (obsolete positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress) |
2020-11-03 | Deleted | RELATION | part of GO:0005634 (nucleus) |
2020-11-03 | Deleted | RELATION | capable of GO:0000977 (RNA polymerase II transcription regulatory region sequence-specific DNA binding) |
2020-04-25 | Added | RELATION | part of GO:0005634 (nucleus) |
2017-11-08 | Deleted | RELATION | part of GO:0005634 (nucleus) |
2017-05-22 | Added | RELATION | part of GO:0005634 (nucleus) |
2017-04-06 | Deleted | RELATION | part of GO:0005634 (nucleus) |
2015-06-18 | Added | RELATION | capable of GO:0001228 (DNA-binding transcription activator activity, RNA polymerase II-specific) |
2015-06-18 | Added | RELATION | capable of part of GO:1990440 (obsolete positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress) |
2015-06-18 | Added | RELATION | capable of GO:0000977 (RNA polymerase II transcription regulatory region sequence-specific DNA binding) |
2014-12-20 | Added | RELATION | is a GO:0090575 (RNA polymerase II transcription regulator complex) |
2014-12-20 | Added | RELATION | part of GO:0005634 (nucleus) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-04 | Deleted | XREF | IntAct:EBI-10043123 |
2021-05-04 | Deleted | XREF | IntAct:EBI-10043370 |
2017-10-07 | Added | XREF | IntAct:EBI-10043123 |
2017-10-07 | Added | XREF | IntAct:EBI-10043370 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
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