GO:1990622
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CHOP-ATF3 complex
Cellular Component
Definition (GO:1990622 GONUTS page)
A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits. PMID:8622660
Acknowledgement
This term was created by the GO Consortium with support from:
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
GADD153-ATF3 complex | exact |
ATF3-CHOP complex | exact |
CHOP-ATF3 heterodimer | exact |
CHOP-ATF3 heterodimeric complex | exact |
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:1990622 | CHOP-ATF3 complex | Only in Taxon | 2759 | Eukaryota |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2JW23 | 10116 | A0A0G2JW23_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2K8T1 | 10116 | A0A0G2K8T1_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1B0GR71 | 10090 | A0A1B0GR71_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1B0GRK6 | 10090 | A0A1B0GRK6_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1D8PHF8 | 237561 | A0A1D8PHF8_CANAL | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5Y8H4 | 10116 | A0A8I5Y8H4_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A0E5 | 10116 | A0A8I6A0E5_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:1990622 based on ALL annotations
The top 100 of 111 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
CHOP-ATF3 complex
|
278,698.80 | 100.00 | 711 | 711 |
CHOP-ATF4 complex
|
240,748.34 | 75.46 | 609 | 705 |
CHOP-C/EBP complex
|
228,435.52 | 72.07 | 609 | 743 |
ER overload response
|
111,626.41 | 37.51 | 608 | 1,518 |
positive regulation of TRAIL-activated apoptotic signaling pathway
|
278,698.80 | 14.35 | 102 | 102 |
intrinsic apoptotic signaling pathway in response to nitrosative stress
|
275,341.00 | 11.52 | 82 | 83 |
response to platelet-derived growth factor
|
134,431.19 | 10.26 | 82 | 170 |
negative regulation of determination of dorsal identity
|
97,323.40 | 10.06 | 88 | 252 |
vascular associated smooth muscle cell migration
|
99,796.09 | 9.56 | 82 | 229 |
vascular associated smooth muscle cell proliferation
|
61,599.20 | 8.20 | 82 | 371 |
Totals | 15883 | 49550219 |
No co-occurrence statistics for GO:1990622 based on MANUAL annotations
The top 100 of 107 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
CHOP-ATF3 complex
|
70,576.65 | 100.00 | 20 | 20 |
CHOP-ATF4 complex
|
63,518.98 | 81.82 | 18 | 20 |
CHOP-C/EBP complex
|
50,815.19 | 66.67 | 18 | 25 |
ER overload response
|
23,097.81 | 31.58 | 18 | 55 |
positive regulation of TRAIL-activated apoptotic signaling pathway
|
70,576.66 | 10.00 | 2 | 2 |
negative regulation of determination of dorsal identity
|
20,164.76 | 8.00 | 2 | 7 |
intrinsic apoptotic signaling pathway in response to nitrosative stress
|
35,288.33 | 4.76 | 1 | 2 |
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
3,274.17 | 4.62 | 18 | 388 |
positive regulation of autophagy in response to ER overload
|
14,115.33 | 4.17 | 1 | 5 |
HRI-mediated signaling
|
4,553.33 | 4.08 | 2 | 31 |
Totals | 362 | 530184 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2022-06-22 | Added | RELATION | is a GO:0140513 (nuclear protein-containing complex) |
2022-06-22 | Added | RELATION | is a GO:0005667 (transcription regulator complex) |
2022-06-22 | Deleted | RELATION | is a GO:0032991 (protein-containing complex) |
2018-02-18 | Added | RELATION | is a GO:0032991 (protein-containing complex) |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2015-02-05 | Added | SYNONYM | CHOP-ATF3 heterodimer |
2015-02-05 | Added | TERM | CHOP-ATF3 complex |
2015-02-05 | Added | DEFINITION | A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits. |
2015-02-05 | Added | SYNONYM | GADD153-ATF3 complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-02-05 | Added | TERM | CHOP-ATF3 complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-02-05 | Added | SYNONYM | CHOP-ATF3 heterodimer |
2015-02-05 | Added | DEFINITION | A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits. |
2015-02-05 | Added | SYNONYM | GADD153-ATF3 complex |
2015-02-05 | Added | SYNONYM | CHOP-ATF3 heterodimeric complex |
2015-02-05 | Added | SYNONYM | ATF3-CHOP complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-06-22 | Added | RELATION | is a GO:0140513 (nuclear protein-containing complex) |
2022-06-22 | Added | RELATION | is a GO:0005667 (transcription regulator complex) |
2022-06-22 | Deleted | RELATION | is a GO:0032991 (protein-containing complex) |
2018-02-18 | Added | RELATION | is a GO:0032991 (protein-containing complex) |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2015-02-05 | Added | RELATION | is a GO:0043234 (protein complex) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
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