GO:1990782
JSON
protein tyrosine kinase binding
Molecular Function
Definition (GO:1990782 GONUTS page)
Binding to protein tyrosine kinase. PMID:25499537
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| tyrosine kinase binding | exact |
Ancestor Chart
Ancestor chart for GO:1990782
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:1990782
| Child Term | Relationship to GO:1990782 |
|---|---|
|
receptor tyrosine kinase binding
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
| Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | P21333-1 | 9606 | FLNA_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
| NOT-qualified manual | protein | P63026 | 9913 | VAMP2_BOVIN | GO:0005515 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699 | |
| NOT-qualified manual | protein | Q86V48 | 9606 | LUZP1_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:1990782 based on ALL annotations
The top 100 of 1,776 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
protein tyrosine kinase binding
|
27,976.12 | 100.00 | 7,083 | 7,083 |
|
interleukin-15-mediated signaling pathway
|
15,843.11 | 23.73 | 2,054 | 3,627 |
|
MHC class II protein binding
|
15,197.82 | 23.31 | 2,054 | 3,781 |
|
T cell activation
|
6,243.60 | 14.52 | 2,080 | 9,320 |
|
negative regulation of B cell activation
|
12,554.88 | 11.70 | 968 | 2,157 |
|
B cell activation
|
4,528.90 | 8.49 | 1,072 | 6,622 |
|
regulation of immune system process
|
2,798.76 | 7.60 | 1,704 | 17,033 |
|
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
|
2,504.99 | 6.03 | 1,106 | 12,352 |
|
positive regulation of ERK1 and ERK2 cascade
|
1,804.32 | 5.67 | 2,265 | 35,119 |
|
membrane raft
|
1,140.74 | 3.78 | 2,398 | 58,810 |
| Totals | 34791 | 320530 | ||
No co-occurrence statistics for GO:1990782 based on MANUAL annotations
The top 100 of 1,640 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
protein tyrosine kinase binding
|
5,955.84 | 100.00 | 237 | 237 |
|
regulation of immune system process
|
616.46 | 8.01 | 62 | 599 |
|
negative regulation of B cell activation
|
1,724.06 | 7.56 | 22 | 76 |
|
B cell activation
|
718.29 | 5.83 | 24 | 199 |
|
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
|
469.17 | 5.47 | 36 | 457 |
|
cellular response to amyloid-beta
|
788.27 | 5.07 | 18 | 136 |
|
cellular response to lipid
|
2,277.23 | 5.04 | 13 | 34 |
|
negative regulation of T cell receptor signaling pathway
|
674.25 | 4.76 | 18 | 159 |
|
regulation of interleukin-6 production
|
1,520.64 | 4.41 | 12 | 47 |
|
scaffold protein binding
|
498.40 | 4.39 | 20 | 239 |
| Totals | 1366 | 8038 | ||
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2021-05-24 | Added | DEFINITION | Binding to protein tyrosine kinase. |
| 2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with protein tyrosine kinase. |
| 2015-06-25 | Added | RELATION | is a GO:0019901 (protein kinase binding) |
| 2015-06-25 | Added | DEFINITION | Interacting selectively and non-covalently with protein tyrosine kinase. |
| 2015-06-25 | Added | TERM | protein tyrosine kinase binding |
| 2015-06-25 | Added | SYNONYM | tyrosine kinase binding |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2015-06-25 | Added | TERM | protein tyrosine kinase binding |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2021-05-24 | Added | DEFINITION | Binding to protein tyrosine kinase. |
| 2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with protein tyrosine kinase. |
| 2015-06-25 | Added | DEFINITION | Interacting selectively and non-covalently with protein tyrosine kinase. |
| 2015-06-25 | Added | SYNONYM | tyrosine kinase binding |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2015-06-25 | Added | RELATION | is a GO:0019901 (protein kinase binding) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|
Please Wait...
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link