This term is obsolete.

GO:2000272 JSON

negative regulation of signaling receptor activity

Biological Process

Definition (GO:2000272 GONUTS page)

Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity.

Restrictions

This term should not be used for direct annotation.

51 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
negative regulation of receptor activity broad
negative regulation of signalling receptor activity exact

Ancestor Chart

Ancestor chart for GO:2000272
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:2000272

Child Term Relationship to
GO:2000272
negative regulation of NMDA glutamate receptor activity
is_a
negative regulation of AMPA receptor activity
is_a
negative regulation of advanced glycation end-product receptor activity
is_a
cross-receptor inhibition within G protein-coupled receptor heterodimer
is_a
negative regulation of corticotropin-releasing hormone receptor activity
is_a
negative regulation of epidermal growth factor-activated receptor activity
is_a

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:

Ontology Development Project
signalling Link

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:2000272 based on ALL annotations
The top 100 of 372 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of signaling receptor activity
22,017,208.00 100.00 9 9
negative regulation of interleukin-11 production
11,008,604.00 10.00 1 2
positive regulation of ferrous iron binding
11,008,604.00 10.00 1 2
positive regulation of transferrin receptor binding
11,008,604.00 10.00 1 2
positive regulation of calcidiol 1-monooxygenase activity
5,504,302.00 8.33 1 4
positive regulation of receptor binding
4,403,441.50 7.69 1 5
negative regulation of bile acid secretion
3,145,315.50 6.67 1 7
positive regulation of signaling receptor activity
3,145,315.50 6.67 1 7
transmembrane receptor protein tyrosine kinase inhibitor activity
2,752,151.00 6.25 1 8
negative regulation of cytotoxic T cell differentiation
2,752,151.00 6.25 1 8
Totals 112 29992
No co-occurrence statistics for GO:2000272 based on MANUAL annotations
The top 100 of 252 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of signaling receptor activity
156,837.00 100.00 9 9
negative regulation of interleukin-11 production
78,418.50 10.00 1 2
negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I
78,418.50 10.00 1 2
negative regulation of branching involved in lung morphogenesis
78,418.50 10.00 1 2
positive regulation of interleukin-33 production
78,418.50 10.00 1 2
positive regulation of ferrous iron binding
78,418.50 10.00 1 2
positive regulation of transferrin receptor binding
78,418.50 10.00 1 2
signaling receptor inhibitor activity
16,224.52 8.57 3 29
positive regulation of calcidiol 1-monooxygenase activity
39,209.25 8.33 1 4
positive regulation of vitamin D biosynthetic process
39,209.25 8.33 1 4
Totals 115 4322

Change Log

Timestamp Action Category Detail
2024-07-26 Deleted SUBSET gocheck_do_not_annotate
2024-07-26 Added SUBSET gocheck_obsoletion_candidate
2023-06-13 Added SUBSET gocheck_do_not_annotate
2020-11-24 Added SYNONYM negative regulation of signalling receptor activity
2018-07-12 Deleted RELATION is a GO:0009968 (negative regulation of signal transduction)
2018-03-05 Added RELATION is a GO:0009968 (negative regulation of signal transduction)
2018-03-05 Added RELATION negatively regulates GO:0038023 (signaling receptor activity)
2018-03-05 Deleted RELATION negatively regulates GO:0004872 (receptor activity)
2018-03-05 Updated TERM negative regulation of signaling receptor activity
2018-03-05 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of receptor activity.
Timestamp Action Category Detail
2018-03-05 Updated TERM negative regulation of signaling receptor activity
2010-12-05 Added TERM negative regulation of receptor activity
Timestamp Action Category Detail
2020-11-24 Added SYNONYM negative regulation of signalling receptor activity
2018-03-05 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of receptor activity.
2018-03-05 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity.
2018-03-05 Added SYNONYM negative regulation of receptor activity
2010-12-05 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of receptor activity.
Timestamp Action Category Detail
2018-07-12 Deleted RELATION is a GO:0009968 (negative regulation of signal transduction)
2018-03-05 Added RELATION is a GO:0009968 (negative regulation of signal transduction)
2018-03-05 Added RELATION negatively regulates GO:0038023 (signaling receptor activity)
2018-03-05 Deleted RELATION negatively regulates GO:0004872 (receptor activity)
2010-12-05 Added RELATION is a GO:0010469 (regulation of signaling receptor activity)
2010-12-05 Added RELATION is a GO:0044092 (negative regulation of molecular function)
2010-12-05 Added RELATION negatively regulates GO:0004872 (receptor activity)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-07-26 Deleted SUBSET gocheck_do_not_annotate
2024-07-26 Added SUBSET gocheck_obsoletion_candidate
2023-06-13 Added SUBSET gocheck_do_not_annotate
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