GO:2000480
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negative regulation of cAMP-dependent protein kinase activity
Biological Process
Definition (GO:2000480 GONUTS page)
Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.
Restrictions
This term should not be used for direct annotation.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
negative regulation of cyclic AMP-dependent protein kinase activity | exact |
negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity | exact |
negative regulation of protein kinase A activity | related |
negative regulation of PKA | related |
negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity | exact |
negative regulation of 3',5'-cAMP-dependent protein kinase activity | exact |
negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity | exact |
negative regulation of STK22 | related |
negative regulation of PKA C | related |
negative regulation of 3',5' cAMP-dependent protein kinase activity | exact |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | C8VKG6 | 227321 | C8VKG6_EMENI | GO:0019220 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:14668368 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:2000480 based on ALL annotations
The top 23 of 23 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of cAMP-dependent protein kinase activity
|
49,538,716.00 | 100.00 | 4 | 4 |
positive regulation of meiotic cell cycle process involved in oocyte maturation
|
4,307,714.50 | 8.00 | 2 | 23 |
regulation of meiotic cell cycle process involved in oocyte maturation
|
538,464.30 | 1.08 | 2 | 184 |
negative regulation of cAMP/PKA signal transduction
|
202,612.34 | 0.41 | 2 | 489 |
negative regulation of protein import into nucleus
|
80,159.73 | 0.16 | 2 | 1,236 |
germinal vesicle
|
71,536.06 | 0.14 | 2 | 1,385 |
molecular function inhibitor activity
|
25,721.04 | 0.05 | 1 | 1,926 |
protein kinase A catalytic subunit binding
|
9,456.96 | 0.02 | 3 | 15,715 |
cAMP-dependent protein kinase inhibitor activity
|
8,136.22 | 0.02 | 3 | 18,266 |
cAMP-dependent protein kinase regulator activity
|
7,079.99 | 0.01 | 1 | 6,997 |
Totals | 48 | 78582325 |
No co-occurrence statistics for GO:2000480 based on MANUAL annotations
The top 16 of 16 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of cAMP-dependent protein kinase activity
|
352,883.25 | 100.00 | 4 | 4 |
positive regulation of meiotic cell cycle process involved in oocyte maturation
|
33,607.93 | 8.70 | 2 | 21 |
regulation of meiotic cell cycle process involved in oocyte maturation
|
28,230.66 | 7.41 | 2 | 25 |
negative regulation of cAMP/PKA signal transduction
|
18,572.80 | 4.55 | 1 | 19 |
germinal vesicle
|
10,857.95 | 2.99 | 2 | 65 |
protein kinase A catalytic subunit binding
|
3,360.79 | 0.95 | 3 | 315 |
cAMP-dependent protein kinase inhibitor activity
|
2,932.55 | 0.83 | 3 | 361 |
molecular function inhibitor activity
|
2,714.49 | 0.75 | 1 | 130 |
cAMP binding
|
763.82 | 0.22 | 1 | 462 |
cAMP-dependent protein kinase complex
|
556.60 | 0.16 | 1 | 634 |
Totals | 31 | 544996 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-26 | Deleted | SUBSET | gocheck_do_not_annotate |
2024-07-26 | Added | SUBSET | gocheck_obsoletion_candidate |
2023-06-13 | Added | SUBSET | gocheck_do_not_annotate |
2011-03-17 | Added | TERM | negative regulation of cAMP-dependent protein kinase activity |
2011-03-17 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity. |
2011-03-17 | Added | SYNONYM | negative regulation of 3',5'-cAMP-dependent protein kinase activity |
2011-03-17 | Added | SYNONYM | negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity |
2011-03-17 | Added | SYNONYM | negative regulation of PKA |
2011-03-17 | Added | SYNONYM | negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity |
2011-03-17 | Added | SYNONYM | negative regulation of cyclic AMP-dependent protein kinase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-03-17 | Added | TERM | negative regulation of cAMP-dependent protein kinase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-03-17 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity. |
2011-03-17 | Added | SYNONYM | negative regulation of 3',5'-cAMP-dependent protein kinase activity |
2011-03-17 | Added | SYNONYM | negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity |
2011-03-17 | Added | SYNONYM | negative regulation of PKA |
2011-03-17 | Added | SYNONYM | negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity |
2011-03-17 | Added | SYNONYM | negative regulation of cyclic AMP-dependent protein kinase activity |
2011-03-17 | Added | SYNONYM | negative regulation of protein kinase A activity |
2011-03-17 | Added | SYNONYM | negative regulation of AMPK |
2011-03-17 | Added | SYNONYM | negative regulation of 3',5' cAMP-dependent protein kinase activity |
2011-03-17 | Added | SYNONYM | negative regulation of PKA C |
2011-03-17 | Added | SYNONYM | negative regulation of STK22 |
2011-03-17 | Added | SYNONYM | negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-03-17 | Added | RELATION | is a GO:0071901 (negative regulation of protein serine/threonine kinase activity) |
2011-03-17 | Added | RELATION | negatively regulates GO:0004691 (cAMP-dependent protein kinase activity) |
2011-03-17 | Added | RELATION | is a GO:2000479 (regulation of cAMP-dependent protein kinase activity) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-26 | Deleted | SUBSET | gocheck_do_not_annotate |
2024-07-26 | Added | SUBSET | gocheck_obsoletion_candidate |
2023-06-13 | Added | SUBSET | gocheck_do_not_annotate |
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