ID AF085716; SV 1; linear; genomic DNA; STD; VRL; 4642 BP. XX AC AF085716; XX DT 11-FEB-1999 (Rel. 58, Created) DT 11-FEB-1999 (Rel. 58, Last updated, Version 1) XX DE Adeno-associated virus 5 DNA binding trs helicase (Rep22) and capsid DE protein (VP1) genes, complete cds. XX KW . XX OS Adeno-associated virus - 5 OC Viruses; Parvoviridae; Parvovirinae; Dependoparvovirus. XX RN [1] RP 1-4642 RX PUBMED; 9882336. RA Chiorini J.A., Kim F., Yang L., Kotin R.M.; RT "Cloning and characterization of adeno-associated virus type 5"; RL J. Virol. 73(2):1309-1319(1999). XX RN [2] RP 1-4642 RA Chiorini J.A., Kim F., Yang L., Kotin R.M.; RT ; RL Submitted (21-AUG-1998) to the INSDC. RL MHB, NHLBI, NIH, 10 Center Dr., Building 10, 7D18, Bethesda, MD 20892, USA XX DR MD5; 11942d86c96863a191b519457683ecf5. DR EuropePMC; PMC103955; 9882336. DR EuropePMC; PMC115897; 11222696. DR EuropePMC; PMC136721; 12438569. DR EuropePMC; PMC2293646; 18035387. DR EuropePMC; PMC2663820; 19381259. DR EuropePMC; PMC303416; 14671090. DR EuropePMC; PMC3209379; 21917944. DR EuropePMC; PMC4842952; 26134901. DR EuropePMC; PMC5088052; 26829320. DR EuropePMC; PMC525000; 15542645. DR EuropePMC; PMC5542637; 28462816. XX FH Key Location/Qualifiers FH FT source 1..4642 FT /organism="Adeno-associated virus - 5" FT /serotype="5" FT /mol_type="genomic DNA" FT /db_xref="taxon:82300" FT CDS 359..2191 FT /codon_start=1 FT /gene="Rep22" FT /product="DNA binding trs helicase" FT /note="non-structural protein" FT /db_xref="GOA:Q9YJC1" FT /db_xref="InterPro:IPR001257" FT /db_xref="InterPro:IPR014015" FT /db_xref="InterPro:IPR014835" FT /db_xref="InterPro:IPR027417" FT /db_xref="PDB:1M55" FT /db_xref="PDB:1RZ9" FT /db_xref="PDB:1UUT" FT /db_xref="UniProtKB/TrEMBL:Q9YJC1" FT /protein_id="AAD13755.1" FT /translation="MATFYEVIVRVPFDVEEHLPGISDSFVDWVTGQIWELPPESDLNL FT TLVEQPQLTVADRIRRVFLYEWNKFSKQESKFFVQFEKGSEYFHLHTLVETSGISSMVL FT GRYVSQIRAQLVKVVFQGIEPQINDWVAITKVKKGGANKVVDSGYIPAYLLPKVQPELQ FT WAWTNLDEYKLAALNLEERKRLVAQFLAESSQRSQEAASQREFSADPVIKSKTSQKYMA FT LVNWLVEHGITSEKQWIQENQESYLSFNSTGNSRSQIKAALDNATKIMSLTKSAVDYLV FT GSSVPEDISKNRIWQIFEMNGYDPAYAGSILYGWCQRSFNKRNTVWLYGPATTGKTNIA FT EAIAHTVPFYGCVNWTNENFPFNDCVDKMLIWWEEGKMTNKVVESAKAILGGSKVRVDQ FT KCKSSVQIDSTPVIVTSNTNMCVVVDGNSTTFEHQQPLEDRMFKFELTKRLPPDFGKIT FT KQEVKDFFAWAKVNQVPVTHEFKVPRELAGTKGAEKSLKRPLGDVTNTSYKSLEKRARL FT SFVPETPRSSDVTVDPAPLRPLNWNSRYDCKCDYHAQFDNISNKCDECEYLNRGKNGCI FT CHNVTHCQICHGIPPWEKENLSDFGDFDDANKEQ" FT CDS 2207..4381 FT /codon_start=1 FT /gene="VP1" FT /product="capsid protein" FT /db_xref="GOA:Q9YIJ1" FT /db_xref="InterPro:IPR001403" FT /db_xref="InterPro:IPR013607" FT /db_xref="InterPro:IPR016184" FT /db_xref="InterPro:IPR036952" FT /db_xref="PDB:3NTT" FT /db_xref="UniProtKB/TrEMBL:Q9YIJ1" FT /protein_id="AAD13756.1" FT /translation="MSFVDHPPDWLEEVGEGLREFLGLEAGPPKPKPNQQHQDQARGLV FT LPGYNYLGPGNGLDRGEPVNRADEVAREHDISYNEQLEAGDNPYLKYNHADAEFQEKLA FT DDTSFGGNLGKAVFQAKKRVLEPFGLVEEGAKTAPTGKRIDDHFPKRKKARTEEDSKPS FT TSSDAEAGPSGSQQLQIPAQPASSLGADTMSAGGGGPLGDNNQGADGVGNASGDWHCDS FT TWMGDRVVTKSTRTWVLPSYNNHQYREIKSGSVDGSNANAYFGYSTPWGYFDFNRFHSH FT WSPRDWQRLINNYWGFRPRSLRVKIFNIQVKEVTVQDSTTTIANNLTSTVQVFTDDDYQ FT LPYVVGNGTEGCLPAFPPQVFTLPQYGYATLNRDNTENPTERSSFFCLEYFPSKMLRTG FT NNFEFTYNFEEVPFHSSFAPSQNLFKLANPLVDQYLYRFVSTNNTGGVQFNKNLAGRYA FT NTYKNWFPGPMGRTQGWNLGSGVNRASVSAFATTNRMELEGASYQVPPQPNGMTNNLQG FT SNTYALENTMIFNSQPANPGTTATYLEGNMLITSESETQPVNRVAYNVGGQMATNNQSS FT TTAPATGTYNLQEIVPGSVWMERDVYLQGPIWAKIPETGAHFHPSPAMGGFGLKHPPPM FT MLIKNTPVPGNITSFSDVPVSSFITQYSTGQVTVEMEWELKKENSKRWNPEIQYTNNYN FT DPQFVDFAPDSTGEYRTTRPIGTRYLTRPL" XX SQ Sequence 4642 BP; 1167 A; 1322 C; 1238 G; 915 T; 0 other; ctctcccccc tgtcgcgttc gctcgctcgc tggctcgttt gggggggtgg cagctcaaag 60 agctgccaga cgacggccct ctggccgtcg cccccccaaa cgagccagcg agcgagcgaa 120 cgcgacaggg gggagagtgc cacactctca agcaaggggg ttttgtaagc agtgatgtca 180 taatgatgta atgcttattg tcacgcgata gttaatgatt aacagtcatg tgatgtgttt 240 tatccaatag gaagaaagcg cgcgtatgag ttctcgcgag acttccgggg tataaaagac 300 cgagtgaacg agcccgccgc cattctttgc tctggactgc tagaggaccc tcgctgccat 360 ggctaccttc tatgaagtca ttgttcgcgt cccatttgac gtggaggaac atctgcctgg 420 aatttctgac agctttgtgg actgggtaac tggtcaaatt tgggagctgc ctccagagtc 480 agatttaaat ttgactctgg ttgaacagcc tcagttgacg gtggctgata gaattcgccg 540 cgtgttcctg tacgagtgga acaaattttc caagcaggag tccaaattct ttgtgcagtt 600 tgaaaaggga tctgaatatt ttcatctgca cacgcttgtg gagacctccg gcatctcttc 660 catggtcctc ggccgctacg tgagtcagat tcgcgcccag ctggtgaaag tggtcttcca 720 gggaattgaa ccccagatca acgactgggt cgccatcacc aaggtaaaga agggcggagc 780 caataaggtg gtggattctg ggtatattcc cgcctacctg ctgccgaagg tccaaccgga 840 gcttcagtgg gcgtggacaa acctggacga gtataaattg gccgccctga atctggagga 900 gcgcaaacgg ctcgtcgcgc agtttctggc agaatcctcg cagcgctcgc aggaggcggc 960 ttcgcagcgt gagttctcgg ctgacccggt catcaaaagc aagacttccc agaaatacat 1020 ggcgctcgtc aactggctcg tggagcacgg catcacttcc gagaagcagt ggatccagga 1080 aaatcaggag agctacctct ccttcaactc caccggcaac tctcggagcc agatcaaggc 1140 cgcgctcgac aacgcgacca aaattatgag tctgacaaaa agcgcggtgg actacctcgt 1200 ggggagctcc gttcccgagg acatttcaaa aaacagaatc tggcaaattt ttgagatgaa 1260 tggctacgac ccggcctacg cgggatccat cctctacggc tggtgtcagc gctccttcaa 1320 caagaggaac accgtctggc tctacggacc cgccacgacc ggcaagacca acatcgcgga 1380 ggccatcgcc cacactgtgc ccttttacgg ctgcgtgaac tggaccaatg aaaactttcc 1440 ctttaatgac tgtgtggaca aaatgctcat ttggtgggag gagggaaaga tgaccaacaa 1500 ggtggttgaa tccgccaagg ccatcctggg gggctcaaag gtgcgggtcg atcagaaatg 1560 taaatcctct gttcaaattg attctacccc tgtcattgta acttccaata caaacatgtg 1620 tgtggtggtg gatgggaatt ccacgacctt tgaacaccag cagccgctgg aggaccgcat 1680 gttcaaattt gaactgacta agcggctccc gccagatttt ggcaagatta ctaagcagga 1740 agtcaaggac ttttttgctt gggcaaaggt caatcaggtg ccggtgactc acgagtttaa 1800 agttcccagg gaattggcgg gaactaaagg ggcggagaaa tctctaaaac gcccactggg 1860 tgacgtcacc aatactagct ataaaagtct ggagaagcgg gccaggctct catttgttcc 1920 cgagacgcct cgcagttcag acgtgactgt tgatcccgct cctctgcgac cgctcaattg 1980 gaattcaagg tatgattgca aatgtgacta tcatgctcaa tttgacaaca tttctaacaa 2040 atgtgatgaa tgtgaatatt tgaatcgggg caaaaatgga tgtatctgtc acaatgtaac 2100 tcactgtcaa atttgtcatg ggattccccc ctgggaaaag gaaaacttgt cagattttgg 2160 ggattttgac gatgccaata aagaacagta aataaagcga gtagtcatgt cttttgttga 2220 tcaccctcca gattggttgg aagaagttgg tgaaggtctt cgcgagtttt tgggccttga 2280 agcgggccca ccgaaaccaa aacccaatca gcagcatcaa gatcaagccc gtggtcttgt 2340 gctgcctggt tataactatc tcggacccgg aaacggtctc gatcgaggag agcctgtcaa 2400 cagggcagac gaggtcgcgc gagagcacga catctcgtac aacgagcagc ttgaggcggg 2460 agacaacccc tacctcaagt acaaccacgc ggacgccgag tttcaggaga agctcgccga 2520 cgacacatcc ttcgggggaa acctcggaaa ggcagtcttt caggccaaga aaagggttct 2580 cgaacctttt ggcctggttg aagagggtgc taagacggcc cctaccggaa agcggataga 2640 cgaccacttt ccaaaaagaa agaaggctcg gaccgaagag gactccaagc cttccacctc 2700 gtcagacgcc gaagctggac ccagcggatc ccagcagctg caaatcccag cccaaccagc 2760 ctcaagtttg ggagctgata caatgtctgc gggaggtggc ggcccattgg gcgacaataa 2820 ccaaggtgcc gatggagtgg gcaatgcctc gggagattgg cattgcgatt ccacgtggat 2880 gggggacaga gtcgtcacca agtccacccg aacctgggtg ctgcccagct acaacaacca 2940 ccagtaccga gagatcaaaa gcggctccgt cgacggaagc aacgccaacg cctactttgg 3000 atacagcacc ccctgggggt actttgactt taaccgcttc cacagccact ggagcccccg 3060 agactggcaa agactcatca acaactactg gggcttcaga ccccggtccc tcagagtcaa 3120 aatcttcaac attcaagtca aagaggtcac ggtgcaggac tccaccacca ccatcgccaa 3180 caacctcacc tccaccgtcc aagtgtttac ggacgacgac taccagctgc cctacgtcgt 3240 cggcaacggg accgagggat gcctgccggc cttccctccg caggtcttta cgctgccgca 3300 gtacggttac gcgacgctga accgcgacaa cacagaaaat cccaccgaga ggagcagctt 3360 cttctgccta gagtactttc ccagcaagat gctgagaacg ggcaacaact ttgagtttac 3420 ctacaacttt gaggaggtgc ccttccactc cagcttcgct cccagtcaga acctgttcaa 3480 gctggccaac ccgctggtgg accagtactt gtaccgcttc gtgagcacaa ataacactgg 3540 cggagtccag ttcaacaaga acctggccgg gagatacgcc aacacctaca aaaactggtt 3600 cccggggccc atgggccgaa cccagggctg gaacctgggc tccggggtca accgcgccag 3660 tgtcagcgcc ttcgccacga ccaataggat ggagctcgag ggcgcgagtt accaggtgcc 3720 cccgcagccg aacggcatga ccaacaacct ccagggcagc aacacctatg ccctggagaa 3780 cactatgatc ttcaacagcc agccggcgaa cccgggcacc accgccacgt acctcgaggg 3840 caacatgctc atcaccagcg agagcgagac gcagccggtg aaccgcgtgg cgtacaacgt 3900 cggcgggcag atggccacca acaaccagag ctccaccact gcccccgcga ccggcacgta 3960 caacctccag gaaatcgtgc ccggcagcgt gtggatggag agggacgtgt acctccaagg 4020 acccatctgg gccaagatcc cagagacggg ggcgcacttt cacccctctc cggccatggg 4080 cggattcgga ctcaaacacc caccgcccat gatgctcatc aagaacacgc ctgtgcccgg 4140 aaatatcacc agcttctcgg acgtgcccgt cagcagcttc atcacccagt acagcaccgg 4200 gcaggtcacc gtggagatgg agtgggagct caagaaggaa aactccaaga ggtggaaccc 4260 agagatccag tacacaaaca actacaacga cccccagttt gtggactttg ccccggacag 4320 caccggggaa tacagaacca ccagacctat cggaacccga taccttaccc gaccccttta 4380 acccattcat gtcgcatacc ctcaataaac cgtgtattcg tgtcagtaaa atactgcctc 4440 ttgtggtcat tcaatgaata acagcttaca acatctacaa aacctccttg cttgagagtg 4500 tggcactctc ccccctgtcg cgttcgctcg ctcgctggct cgtttggggg ggtggcagct 4560 caaagagctg ccagacgacg gccctctggc cgtcgccccc ccaaacgagc cagcgagcga 4620 gcgaacgcga caggggggag ag 4642 //