ID HM745931; SV 1; linear; viral cRNA; STD; VRL; 3378 BP. XX AC HM745931; XX DT 09-MAR-2011 (Rel. 108, Created) DT 10-AUG-2011 (Rel. 109, Last updated, Version 3) XX DE Phlebovirus HB29/China/2010 strain HB29 segment M, complete sequence. XX KW . XX OS SFTS virus HB29 OC Viruses; Riboviria; Negarnaviricota; Polyploviricotina; Ellioviricetes; OC Bunyavirales; Phenuiviridae; Phlebovirus. XX RN [1] RP 1-3378 RX DOI; 10.1056/NEJMoa1010095. RX PUBMED; 21410387. RA Yu X.J., Liang M.F., Zhang S.Y., Liu Y., Li J.D., Sun Y.L., Zhang L., RA Zhang Q.F., Popov V.L., Li C., Qu J., Li Q., Zhang Y.P., Hai R., Wu W., RA Wang Q., Zhan F.X., Wang X.J., Kan B., Wang S.W., Wan K.L., Jing H.Q., RA Lu J.X., Yin W.W., Zhou H., Guan X.H., Liu J.F., Bi Z.Q., Liu G.H., Ren J., RA Wang H., Zhao Z., Song J.D., He J.R., Wan T., Zhang J.S., Fu X.P., RA Sun L.N., Dong X.P., Feng Z.J., Yang W.Z., Hong T., Zhang Y., Walker D.H., RA Wang Y., Li D.X.; RT "Fever with thrombocytopenia associated with a novel bunyavirus in China"; RL N. Engl. J. Med. 364(16):1523-1532(2011). XX RN [2] RP 1-3378 RA Li J., Sun Y., Liang M., Zhang Q., Lu J., Li C., Qu J., Zhan F., Li D.; RT "A novel Phlebovirus related to severe fever with thrombocytopenia syndrome RT (SFTS) in humans"; RL Unpublished. XX RN [3] RP 1-3378 RA Li J., Sun Y., Liang M., Zhang Q., Lu J., Li C., Qu J., Zhan F., Li D.; RT ; RL Submitted (11-JUL-2010) to the INSDC. RL Department of Viral Hemorrhagic Fever, National Institute for Viral RL Diseases Control and Prevention, Changbai Road 155, Beijing 102206, China XX DR MD5; 9af8d47fd0456a6f780a6cca5172a514. DR EuropePMC; PMC3165796; 21715500. DR EuropePMC; PMC3503025; 23035232. DR EuropePMC; PMC4337530; 25552716. XX CC GenBank Accession Numbers HM745930-HM745932 represent sequences CC from the 3 segments of Phlebovirus HB29/China/2010. XX FH Key Location/Qualifiers FH FT source 1..3378 FT /organism="SFTS virus HB29" FT /segment="M" FT /host="Homo sapiens" FT /strain="HB29" FT /mol_type="viral cRNA" FT /country="China" FT /isolation_source="serum" FT /collection_date="20-May-2010" FT /db_xref="taxon:992212" FT CDS 19..3240 FT /codon_start=1 FT /product="membrane glycoprotein polyprotein" FT /db_xref="GOA:F1BA47" FT /db_xref="InterPro:IPR009878" FT /db_xref="InterPro:IPR010826" FT /db_xref="UniProtKB/TrEMBL:F1BA47" FT /protein_id="ADZ04471.1" FT /translation="MMKVIWFSSLICLVIQCSGDSGPIICAGPIHSNKSAGIPHLLGYS FT EKICQIDRLIHVSSWLRNHSQFQGYVGQRGGRSQVSYYPAENSYSRWSGLLSPCDADWL FT GMLVVKKAKESDMIVPGPSYKGKVFFERPTFDGYVGWGCGSGKSRTESGELCSSDSGTS FT SGLLPSDRVLWIGDVACQPMTPIPEETFLELKSFSQSEFPDICKIDGIVFNQCEGESLP FT QPFDVAWMDVGHSHKIIMREHKTKWVQESSSKDFVCYKEGTGPCSESEEKACKTSGSCR FT GDMQFCKVAGCEHGEEASEAKCRCSLVHKPGEVVVSYGGTRVRPKCYGFSRMMATLEVN FT PPEQRIGQCTGCHLECINGGVRLITLTSELRSATVCASHFCSSASSGKKSTEIHFHSGS FT LVGKTAIHVKGALVDGTEFTFEGSCMFPDGCDAVDCTFCREFLKNPQCYPAKKWLFIII FT VILLGYAGLMLLTNVLKAIGVWGSWVIAPVKLMFAIIKKLMRTVSCLVGKLMDRGRQVI FT HEEIGENGEGNQDDVRIEMARPRRVRHWMYSPVILTILAIGLAEGCDEMVHADSKLVSC FT RQGSGNMKECITTGRALLPAVNPGQEACLHFTAPGSPDSKCLKIKVKRINLKCKKSSSY FT FVPDARSRCTSVRRCRWAGDCQSGCPPHFTSNSFSDDWAGKMDRAGLGFSGCSDGCGGA FT ACGCFNAAPSCIFWRKWVENPHGIIWKVSPCAAWVPSAVIELTMPSGEVRTFHPMSGIP FT TQVFKGVSVTYLGSDMEVSGLTDLCEIEELKSKKLALAPCNQAGMGVVGKVGEIQCSSE FT ESARTIKKDGCIWNADLVGIELRVDDAVCYSKITSVEAVANYSAIPTTIGGLRFERSHD FT SQGKISGSPLDITAIRGSFSVNYRGLRLSLSEITATCTGEVTNVSGCYSCMTGAKVSIK FT LHSSKNSTAHVRCKGDETAFSVLEGVHSYIVRLSFDHAVVDEQCQLNCGGHESQVTLKG FT NLIFLDVPKFVDGSYMQTYHSTVPTGANIPSPTDWLNALFGNGLSRWILGVIGVLLGGL FT ALFFLIMFLLKLGTKQVFRSRTKLA" FT sig_peptide 19..75 FT mat_peptide 76..1623 FT /product="Gn protein" FT sig_peptide 1624..1704 FT mat_peptide 1705..3237 FT /product="Gc glycoprotein" XX SQ Sequence 3378 BP; 858 A; 697 C; 967 G; 856 T; 0 other; acacagagac ggccaacaat gatgaaagtc atctggttct cctctctgat ctgcttagtc 60 attcaatgca gtggggattc gggcccaatc atctgcgcag gacccatcca ctcaaacaag 120 agtgctggca taccccacct gcttggttac tctgagaaga tttgtcagat agatcggctg 180 atacatgttt cgtcatggct caggaaccac tcgcaatttc aaggctacgt tgggcagcga 240 ggtggacgct ctcaggttag ctactaccca gctgagaatt cttactcgag gtggagtgga 300 cttctaagcc cctgtgatgc tgattggctt gggatgcttg tcgtgaagaa ggctaaggag 360 tctgatatga tagttcctgg gccttcatac aaggggaaag tcttttttga acggccaact 420 tttgatggat acgtaggctg gggctgtggc agtgggaagt ctaggactga gtcaggagag 480 ctctgcagtt cagactcagg gacaagttct ggtcttctgc cctcggatag ggttctctgg 540 ataggtgatg ttgcttgtca gcctatgaca cccatccctg aggagacatt tctggagctg 600 aagagtttta gccaaagtga attcccagac atatgtaaaa ttgatggcat tgtgttcaac 660 cagtgtgagg gtgagagtct accccagccc tttgatgttg catggatgga tgttggccac 720 tctcataaga tcatcatgag ggagcacaag accaaatggg tacaagagag ctcatccaag 780 gattttgtgt gctacaagga agggactgga ccttgttctg aatcagaaga aaaggcttgt 840 aagaccagtg gatcatgcag aggggacatg cagttttgca aggtggcagg ttgcgaacat 900 ggagaggagg catctgaggc caagtgtaga tgctcacttg tgcacaagcc tggggaagtc 960 gttgtgtcat atggagggac gcgtgtcaga ccaaagtgct acggtttctc cagaatgatg 1020 gcaacactgg aggtgaaccc accagagcaa aggattggtc aatgcactgg ctgccatcta 1080 gaatgcataa atgggggtgt gaggctaatc actctaacca gtgagctcag gtcagctact 1140 gtctgtgctt cccacttttg cagttctgcc tcaagtggta agaaaagcac ggagattcat 1200 ttccactcag gatcattggt tgggaaaaca gctatccatg tcaaaggggc attggtagat 1260 ggaactgaat tcacatttga gggtagttgc atgttcccag atggatgtga tgcagtggac 1320 tgcacattct gtcgtgagtt tctaaaaaat cctcagtgct accctgcaaa gaagtggctg 1380 ttcatcatta ttgtcatcct ccttggatat gcaggcctca tgttactcac caatgtcctt 1440 aaggcaattg gggtctgggg atcatgggta atagctccag tgaagctaat gtttgccatc 1500 ataaagaaac taatgagaac tgtgagctgc ttggtgggga aattgatgga taggggaagg 1560 caagtgatcc atgaggaaat aggggagaat ggggagggca accaagatga tgttaggatt 1620 gagatggcaa gacccagaag ggtaaggcat tggatgtact cacctgtcat cctgaccatt 1680 ctagcaatag ggcttgcaga gggctgtgat gagatggtcc atgctgattc taaacttgtt 1740 tcatgcagac aagggagcgg aaacatgaag gaatgcataa caactgggag ggcgcttctt 1800 cctgcggtga acccaggaca agaggcatgt ctgcacttca cagcacctgg gagtccggac 1860 tcaaaatgtc tcaaaattaa ggttaagagg atcaacctaa aatgtaagaa gtcatcatca 1920 tattttgttc ctgatgcccg gtccaggtgt acatcagtga ggagatgtcg ttgggcggga 1980 gactgccagt ctgggtgccc ccctcatttc acatccaact ccttttctga tgattgggca 2040 ggtaagatgg acagggctgg tcttggattc agtggctgct ctgatggatg tggaggagca 2100 gcctgcggct gctttaatgc ggccccttca tgcatcttct ggaggaaatg ggtggagaat 2160 ccacatggga tcatctggaa agtgtctcca tgcgccgcat gggtcccatc agcagttata 2220 gagctaacaa tgccctcagg tgaggtgagg acattccacc ccatgagcgg catccccaca 2280 caggtcttca agggtgtgag tgtaacttac ttgggctcag atatggaggt gtctggcttg 2340 actgacctgt gtgagataga agagctcaag tccaaaaagc tggcattagc tccctgcaac 2400 caggctggca tgggggttgt aggcaaggtt ggagagatac agtgcagtag cgaggagagt 2460 gcccgtacca taaaaaaaga tgggtgcata tggaacgcag acctcgtggg tatagagcta 2520 cgagtggatg acgctgtgtg ctactctaag attactagtg tggaggcagt tgcaaactac 2580 tctgccatac ccaccactat tggggggctg aggtttgaga gaagccatga cagccagggt 2640 aaaatatctg gtagccccct ggacatcaca gctataagag gatccttttc tgttaattat 2700 agaggccttc gattaagtct ctcagaaatt actgctactt gcacagggga ggtgacaaat 2760 gtgagtgggt gctattcctg catgacaggt gccaaagtct ccatcaaatt gcatagcagc 2820 aaaaatagca ctgcccatgt tagatgcaaa ggggatgaga ctgcattcag tgtcttggag 2880 ggagtccata gctacattgt ccgcctcagc tttgaccatg cagtagtcga tgagcaatgc 2940 cagctgaact gtgggggaca tgagagtcaa gtgactctta aaggcaacct catcttcctg 3000 gatgtcccaa aatttgtgga tggcagctac atgcagacat atcacagtac tgtgccaaca 3060 ggggcaaata tcccaagccc tacagattgg ctgaatgcct tgtttggcaa tgggctgagt 3120 aggtggatcc tgggggtgat aggggttcta ctggggggat tggctctctt tttcttgatc 3180 atgtttttgc tcaagctggg aacaaaacag gtatttcgat cgaggacgaa gctggcttag 3240 atgggcaaat ttctggtcta gtgaccctct gggagcagtg ctctcagggg agttggctca 3300 cagtgtgttt gtttcgtggt cctggctcac attcttagaa tatggaggtt ctattgaagt 3360 gttggccggt ctttgtgt 3378 //