Markevich2004_MAPK_phosphoRandomMM

Model Identifier
BIOMD0000000029
Short description

The model corresponds to the schema 3 of Markevich et al 2004, as described in the figure 2 and the supplementary table S3, and modelled using Michaelis-Menten like kinetics. Phosphorylations follow distributive random kinetics, while dephosphorylations follow an ordered mechanism.

This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2007 The BioModels Team.
For more information see the terms of use .

Format
SBML (L2V1)
Related Publication
  • Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades.
  • Nick I Markevich, Jan B Hoek, Boris N Kholodenko
  • The Journal of cell biology , 2/ 2004 , Volume 164 , Issue 3 , pages: 353-359 , PubMed ID: 14744999
Contributors
Submitter of the first revision: Nicolas Le Novère
Submitter of this revision: Lucian Smith
Curator: Lucian Smith
Modeller: Nicolas Le Novère

Metadata information

is (2 statements)
BioModels Database BIOMD0000000029
BioModels Database MODEL6618620128

isDescribedBy (1 statement)
PubMed 14744999

hasTaxon (1 statement)
Taxonomy Xenopus laevis

isVersionOf (1 statement)
Gene Ontology MAPK cascade

hasProperty (1 statement)
Mathematical Modelling Ontology Ordinary differential equation model

Curation status
Curated
Modelling approach(es)
ordinary differential equation model

Connected external resources