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ChEBI
> Main
CHEBI:91182 - ZM 323881 hydrochloride
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ChEBI Name
ZM 323881 hydrochloride
ChEBI ID
CHEBI:91182
Definition
A hydrochloride obtained by combining ZM 323881 with one molar equivalent of hydrochloric acid.
Stars
This entity has been manually annotated by the ChEBI Team.
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Formula
C22H19ClFN3O2
Net Charge
0
Average Mass
411.857
Monoisotopic Mass
411.11498
InChI
InChI=1S/C22H18FN3O2.ClH/c1-
14-
9-
18(23)
20(11-
21(14)
27)
26-
22-
17-
8-
7-
16(10-
19(17)
24-
13-
25-
22)
28-
12-
15-
5-
3-
2-
4-
6-
15;/h2-
11,13,27H,12H2,1H3,(H,24,25,26)
;1H
InChIKey
AVRHWGLIYGJSOD-UHFFFAOYSA-N
SMILES
C1(O)=C(C=C(C(=C1)NC=2N=CN=C3C2C=CC(=C3)OCC4=CC=CC=C4)F)C.Cl
Roles Classification
Biological Role
(s):
vascular endothelial growth factor receptor antagonist
An antagonist at the vascular endothelial growth factor receptor.
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that interferes with the action of receptor protein-tyrosine kinase (EC 2.7.10.1).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
ZM 323881 hydrochloride (
CHEBI:91182
)
has part
ZM 323881(1+) (
CHEBI:91187
)
ZM 323881 hydrochloride (
CHEBI:91182
)
has role
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor (
CHEBI:62434
)
ZM 323881 hydrochloride (
CHEBI:91182
)
has role
vascular endothelial growth factor receptor antagonist (
CHEBI:65207
)
ZM 323881 hydrochloride (
CHEBI:91182
)
is a
hydrochloride (
CHEBI:36807
)
IUPAC Names
5-{[7-(benzyloxy)quinazolin-4-yl]amino}-4-fluoro-2-methylphenol hydrochloride
7-(benzyloxy)-
N
-(2-fluoro-5-hydroxy-4-methylphenyl)quinazolin-4-aminium chloride
Synonyms
Sources
ZM 323881 monohydrochloride
ChEBI
ZM 323881.HCl
ChEBI
ZM-323881 hydrochloride
ChEBI
ZM-323881 monohydrochloride
ChEBI
ZM-323881.HCl
ChEBI
Registry Number
Type
Source
13172661
Reaxys Registry Number
Reaxys
Last Modified
15 February 2016