7-chloro-5,10-dihydrothieno[3,4-b][1,5]benzodiazepin-4-one (CHEBI:93715)

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ChEBI Name	7-chloro-5,10-dihydrothieno[3,4-b][1,5]benzodiazepin-4-one

ChEBI ID	CHEBI:93715

Stars	This entity has been manually annotated by a third party.

Supplier Information

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Formula

C11H7ClN2OS

Net Charge

Average Mass

250.706

Monoisotopic Mass

249.99676

InChI

InChI=1S/C11H7ClN2OS/c12-6-1-2-8-9(3-6)14-11(15)7-4-16-5-10(7)13-8/h1-5,13H,(H,14,15)

InChIKey

PHNFXXZEKWQHDX-UHFFFAOYSA-N

SMILES

C1=CC2=C(C=C1Cl)NC(=O)C3=CSC=C3N2

Roles Classification
Biological Role(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

Application(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

ChEBI Ontology
Outgoing	7-chloro-5,10-dihydrothieno[3,4-b][1,5]benzodiazepin-4-one (CHEBI:93715) is a benzodiazepine (CHEBI:22720)