InChI=1S/C18H15ClO7/c1-23-11-7-10(20)12-14(22)18(25-3)15(26-17(12)16(11)24-2)8-5-4-6-9(19)13(8)21/h4-7,20-21H,1-3H3 |
JLSQXYITDXJTKL-UHFFFAOYSA-N |
COc1cc(O)c2c(oc(-c3cccc(Cl)c3O)c(OC)c2=O)c1OC |
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Aspergillus candidus
(NCBI:txid41067)
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See:
PubMed
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Aspergillus metabolite
Any fungal metabolite produced during a metabolic reaction in the mould, Aspergillus .
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
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View more via ChEBI Ontology
2-(3-chloro-2-hydroxyphenyl)-5-hydroxy-3,7,8-trimethoxy-4H-1-benzopyran-4-one
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3'-chloro-2',5-dihydroxy-3,7,8-trimethoxyflavone
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ChEBI
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1300439
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Reaxys Registry Number
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Reaxys
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23363-64-6
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CAS Registry Number
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KEGG COMPOUND
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23363-64-6
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CAS Registry Number
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ChemIDplus
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Marchelli R, Vining LC (1973) The biosynthetic origin of chlorflavonin, a flavonoid antibiotic from Aspergillus candidus. Canadian journal of biochemistry 51, 1624-1629 [PubMed:4775434] | Munden JE, Butterworth D, Hanscomb G, Verrall MS (1970) Production of chlorflavonin, an antifungal metabolite of Aspergillus candidus. Applied microbiology 19, 718-720 [PubMed:5463573] [show Abstract] Production of chlorflavonin, a new antifungal antibiotic, by strains of Aspergillus candidus is described. Two wild strains of the fungus had distinctly different chlorflavonin-producing capabilities. One strain produced 25 mug of chlorflavonin per ml per 4 to 5 days in a pilot scale fermentor with stirring, using a medium containing corn steep liquor and glucose. Production of antibiotic was favored by high rates of agitation-aeration. Crude chlorflavonin was extracted from the whole brew with a hydrocarbon solvent and then purified by recrystallization from benzene and petroleum ether. The overall yield from fermentation brew to pure product was 50%. | Bird AE, Marshall AC (1969) Structure of chlorflavonin. Journal of the Chemical Society. Perkin transactions 1 18, 2418-2420 [PubMed:5391291] |
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