disuccinimidyl suberate (CHEBI:229718)

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ChEBI Name	disuccinimidyl suberate

ChEBI ID	CHEBI:229718

Definition	A N-hydroxysuccinimide ester resulting from the formal condensation of the two carboxy groups of suberic acid with the hydroxy group of 1-hydroxypyrrolidine-2,5-dione. It is a noncleavable and membrane permeable crosslinker.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Kalpana P

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Formula

C16H20N2O8

Net Charge

Average Mass

368.342

Monoisotopic Mass

368.12197

InChI

InChI=1S/C16H20N2O8/c19-11-7-8-12(20)17(11)25-15(23)5-3-1-2-4-6-16(24)26-18-13(21)9-10-14(18)22/h1-10H2

InChIKey

ZWIBGKZDAWNIFC-UHFFFAOYSA-N

SMILES

O=C(CCCCCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O

Roles Classification
Application(s):	cross-linking reagent A reagent with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between macromolecules, principally side chains of amino acids in proteins, allowing the locations of naturally reactive areas within the proteins to be identified.

ChEBI Ontology
Outgoing	disuccinimidyl suberate (CHEBI:229718) has functional parent suberic acid (CHEBI:9300) disuccinimidyl suberate (CHEBI:229718) has role cross-linking reagent (CHEBI:50684) disuccinimidyl suberate (CHEBI:229718) is a N-hydroxysuccinimide ester (CHEBI:53165) disuccinimidyl suberate (CHEBI:229718) is a diester (CHEBI:51307)

IUPAC Name

1,1'-[(1,8-dioxooctane-1,8-diyl)bis(oxy)]dipyrrolidine-2,5-dione

Synonyms	Sources
1,1'-[(1,8-dioxooctane-1,8-diyl)bis(oxy)]di(pyrrolidine-2,5-dione)	IUPAC
DSS	ChEBI
octanedioic acid di-N-hydroxysuccinimide ester	ChEBI
suberic acid bis(N-hydroxy succinimide ester)	ChEBI

Registry Number	Type	Source
68528-80-3	CAS Registry Number	SUBMITTER

Last Modified

11 March 2024