CHEBI:15864 - luteolin

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name luteolin
ChEBI ID CHEBI:15864
Definition A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3', 4', 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:12082, CHEBI:14536, CHEBI:6578, CHEBI:25086
Supplier Information
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Roles Classification
Chemical Role(s): radical scavenger
A role played by a substance that can react readily with, and thereby eliminate, radicals.
Biological Role(s): vascular endothelial growth factor receptor antagonist
An antagonist at the vascular endothelial growth factor receptor.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
c-Jun N-terminal kinase inhibitor
An EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor that inhibits the action of c-Jun N-terminal kinase.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
EC 2.3.1.85 (fatty acid synthase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of fatty acid synthase (EC 2.3.1.85), a multi-enzyme protein involved in fatty acid synthesis.
immunomodulator
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
Application(s): nephroprotective agent
Any protective agent that is able to prevent damage to the kidney.
angiogenesis inhibitor
An agent and endogenous substances that antagonize or inhibit the development of new blood vessels.
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
immunomodulator
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
Related Structures
luteolin is a Functional Parent of
carlinoside
Mass: 580.49150
Formula: C26H28O15
3421
ochnaflavone
Mass: 538.464
Formula: C30H18O10
194126
6-hydroxyluteolin 7-O-laminaribioside
Mass: 626.51690
Formula: C27H30O17
66046
cassiaoccidentalin B
Mass: 576.50280
Formula: C27H28O14
70205
6-hydroxyluteolin
Mass: 302.23570
Formula: C15H10O7
2197
luteolin O-glucuronoside
Definition: A glycosyloxyflavone that is an O-glucuronidated derivative of luteolin.
6-methoxyluteolin 7-alpha-L-rhamnoside
Mass: 462.40348
Formula: C22H22O11
28314
lucenin-2
Mass: 610.51750
Formula: C27H30O16
6553
orientin
Mass: 448.37690
Formula: C21H20O11
7781
luteolin 7-O-(6-O-malonyl-beta-D-glucoside)
Mass: 534.42308
Formula: C24H22O14
6579
luteolin 7-O-beta-D-glucoside
Mass: 448.37690
Formula: C21H20O11
27994
4',5,7-trihydroxy-3'-methoxyflavone
Mass: 300.26290
Formula: C16H12O6 C16H12O6
16514
diosmetin
Mass: 300.266
Formula: C16H12O6
4630
luteolin 7-O-neohesperidoside
Mass: 594.51810
Formula: C27H30O15
31788
5,3'-di-O-methylluteolin
Mass: 314.28950
Formula: C17H14O6
69455
luteolin-4'-O-beta-D-glucopyranoside
Mass: 448.37690
Formula: C21H20O11
68986
luteolin-7-O-alpha-L-rhamnoside
Mass: 432.37750
Formula: C21H20O10
70030
isoorientin
Mass: 448.37690
Formula: C21H20O11
17965
hypolaetin
Mass: 302.23570
Formula: C15H10O7
5837
maysin
Mass: 576.50280
Formula: C27H28O14
70206
luteolin is a Structural Derivative of
1-benzopyran phenylpropanoid
Definition : Any organic aromatic compound with a structure based on a phenylpropane skeleton. The class includes naturally occurring phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules as well as their semi-synthetic and synthetic analogues. Phenylpropanoids are also precursors of lignin.
luteolin is a Conjugate Acid of
luteolin-7-olate
Mass : 285.22840
Formula : C15H9O6
57545
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