CHEBI:79034 - monacolin J

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ChEBI Name monacolin J
ChEBI ID CHEBI:79034
Definition A polyketide that is monacolin L bearing an additional hydroxy substituent at position 8.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Kristian Axelsen
Supplier Information
Download Molfile XML SDF
Roles Classification
Biological Role(s): antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
fungal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme.
Related Structures
monacolin J is a Functional Parent of
monacolin J acid
Mass : 338.43850
Formula : C19H30O5
82971
monacolin J is a Structural Derivative of
monacolin L
Mass : 304.42380
Formula : C19H28O3
50130
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