CHEBI:38637 - tyrosine kinase inhibitor

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ChEBI Name tyrosine kinase inhibitor
ChEBI ID CHEBI:38637
Definition Any protein kinase inhibitor that interferes with the action of tyrosine kinase.
Stars This entity has been manually annotated by the ChEBI Team.
Members of tyrosine kinase inhibitor Class Download as Tab-delimited, XML, SDF
radicicol
Mass :364.77700
Formula : C18H17ClO6 C18H17ClO6
PP121
Mass :319.372
Formula : C17H17N7
4,5-dianilinophthalimide
Mass :329.35200
Formula : C20H15N3O2
genistein
Mass :270.240
Formula : C15H10O5
sorafenib
Mass :464.826
Formula : C21H16ClF3N4O3
pazopanib
Mass :437.520
Formula : C21H23N7O2S
axitinib
Mass :386.47000
Formula : C22H18N4OS
melemeleone B
Mass :435.57700
Formula : C23H33NO5S
masitinib
Mass :498.64200
Formula : C28H30N6OS
hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester
Mass :454.36440
Formula : C20H23O10P
piceatannol
Mass :244.246
Formula : C14H12O4 C14H12O4
emodin(1-)
Mass :269.22950
Formula : C15H9O5
biochanin A
Mass :284.26348
Formula : C16H12O5
DCC-2036
Mass :553.588
Formula : C30H28FN7O3
dasatinib (anhydrous)
Mass :488.00652
Formula : C22H26ClN7O2S
picropodophyllotoxin
Mass :414.40530
Formula : C22H22O8
leflunomide
Mass :270.20730
Formula : C12H9F3N2O2
pazopanib hydrochloride
Mass :473.97900
Formula : C21H24ClN7O2S
afatinib
Mass :485.93800
Formula : C24H25ClFN5O3
neratinib
Mass :557.050
Formula : C30H29ClN6O3
canertinib
Mass :485.93800
Formula : C24H25ClFN5O3
WZ4002
Mass :494.97300
Formula : C25H27ClN6O3
brigatinib
Mass :584.100
herbimycin
Mass :574.66250
Formula : C30H42N2O9
ponatinib
Mass :532.55950
Formula : C29H27F3N6O
butein
Mass :272.256
Formula : C15H12O5
regorafenib hydrate
Mass :500.831
Formula : C21H15ClF4N4O3.H2O C21H17ClF4N4O4
regorafenib
Mass :482.816
Formula : C21H15ClF4N4O3
afatinib dimaleate
Mass :718.08300
Formula : C32H33ClFN5O11
nintedanib
Mass :539.62480
Formula : C31H33N5O4
nintedanib esylate
Mass :649.75700
Formula : C33H39N5O7S
bosutinib hydrate
Mass :548.46100
Formula : C26H31Cl2N5O4
dasatinib monohydrate
Mass :506.02100
Formula : C22H28ClN7O3S
BE-23372M
Mass :312.27360
Formula : C17H12O6
lapatinib
Mass :581.05840
Formula : C29H26ClFN4O4S
1-NM-PP1
Mass :331.41420
Formula : C20H21N5
1-NA-PP1
Mass :317.38770
Formula : C19H19N5
nilotinib
Mass :529.51580
Formula : C28H22F3N7O
bosutinib
Mass :530.44576
Formula : C26H29Cl2N5O3
teriflunomide
Mass :270.20730
Formula : C12H9F3N2O2
imatinib
Mass :493.60270
Formula : C29H31N7O
PD173955
Mass :443.34950
Formula : C21H16Cl2N4OS
vandetanib
Mass :475.35412
Formula : C22H24BrFN4O2
emodin
Mass :270.23690
Formula : C15H10O5
cabozantinib
Mass :501.50570
Formula : C28H24FN3O5
cabozantinib malate
Mass :635.59310
Formula : C32H30FN3O10
imatinib methanesulfonate
Mass :589.70968
Formula : C29H31N7O.CH4O3S C30H35N7O4S
ponatinib hydrochloride
Mass :569.030
Formula : C29H27F3N6O.ClH
SKLB-677
Mass :411.390
Formula : C19H18FN7O3
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enzyme inhibitor
biological role
inhibitor
protein kinase inhibitor
tyrosine kinase inhibitor
role
biochemical role
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
EC 2.* (transferase) inhibitor
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
EC 2.7.* (P-containing group transferase) inhibitor
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