CHEBI:125562 - 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide

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ChEBI Name 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
ChEBI ID CHEBI:125562
ChEBI ASCII Name 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
Definition A benzamide resulting from the formal condensation of the carboxy group of 4-(dimethylamino)benzoic acid with the amino group of 7-amino-N-hydroxyheptanamide. It is a potent inhibitor of histone deacetylases and induces cell cycle arrest and apoptosis in several human cancer cell lines.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
EC 3.5.1.98 (histone deacetylase) inhibitor
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
Related Structures
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
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