CHEBI:133017 - pimavanserin

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ChEBI Name pimavanserin
ChEBI ID CHEBI:133017
Definition A member of the class of ureas in which three of the four hydrogens are replaced by 4-fluorobenzyl, 1-methylpiperidin-4-yl, and 4-(isopropyloxy)benzyl groups. An atypical antipsychotic that is used (in the form of its tartrate salt) for treatment of hallucinations and delusions associated with Parkinson's disease.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ZINC000085588513
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): 5-hydroxytryptamine 2A receptor inverse agonist
An inverse agonist that binds to the same receptor as a 5-hydroxytryptamine 2A receptor agonist, but which induces a pharmacological response opposite to that agonist.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
Application(s): antipsychotic agent
Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
Related Structures
pimavanserin is a Structural Derivative of
urea
Mass : 60.05534
Formula : CH4N2O
16199
ammonia
Mass : 17.03056
Formula : H3N
16134
pimavanserin is a Conjugate Base of
pimavanserin(1+)
Mass : 428.564
Formula : C25H35FN3O2
133020
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heterocyclic compound
organohalogen compound
benzenes
molecular entity
fluorine molecular entity
chemical entity
halogen molecular entity
organic heterocyclic compound
molecule
organic heteromonocyclic compound
ether
oxygen molecular entity
piperidines
amide
primary amide
heteroorganic entity
pnictogen molecular entity
chalcogen molecular entity
main group molecular entity
carbon group molecular entity
cyclic compound
homocyclic compound
carbocyclic compound
aromatic compound
organic aromatic compound
monocyclic compound
heteromonocyclic compound
p-block molecular entity
organic cyclic compound
benzenoid aromatic compound
organonitrogen compound
fluorobenzenes
aromatic ether
polyatomic entity
organochalcogen compound
organooxygen compound
organofluorine compound
heteroatomic molecular entity
halide
organonitrogen heterocyclic compound
ureas
organic amino compound
organic molecular entity
tertiary amino compound
nitrogen molecular entity
organic molecule
monofluorobenzenes
pimavanserin
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