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InChI=1S/CH4O/c1-2/h2H,1H3
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> ChEBI Ontology
CHEBI:133818 - HG-9-91-01
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ChEBI Name
HG-9-91-01
ChEBI ID
CHEBI:133818
Definition
A member of the class of phenylureas that is a potent inhibitor of salt-inducible kinase 2, a potential target protein for therapy in ovarian cancer.
Stars
This entity has been manually annotated by the ChEBI Team.
Submitter
Margaret Duesbury
Supplier Information
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Roles Classification
Chemical Role
(s):
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Br
o
nsted acid).
(via
organic amino compound
)
Biological Role
(s):
salt-inducible kinase 2 inhibitor
Any protein kinase inhibitor that interferes with the action of salt-inducible kinase 2.
Application
(s):
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
Related Structures
HG-9-91-01 is a
Structural Derivative
of
ammonia
Mass : 17.03056
Formula : H3N
urea
Mass : 60.05534
Formula : CH4N2O
Graph View
Tree View
CHEBI:24431 chemical entity
CHEBI:23367 molecular entity
CHEBI:33579 main group molecular entity
CHEBI:33675 p-block molecular entity
CHEBI:33582 carbon group molecular entity
CHEBI:50860 organic molecular entity
CHEBI:33285 heteroorganic entity
CHEBI:36962 organochalcogen compound
CHEBI:36963 organooxygen compound
CHEBI:25698 ether
CHEBI:35618 aromatic ether
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:24532 organic heterocyclic compound
CHEBI:25693 organic heteromonocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:38101 organonitrogen heterocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:35352 organonitrogen compound
CHEBI:38101 organonitrogen heterocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:50047 organic amino compound
CHEBI:33860 aromatic amine
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:50996 tertiary amino compound
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:50995 secondary amino compound
CHEBI:133818 HG-9-91-01
CHEBI:72695 organic molecule
CHEBI:33832 organic cyclic compound
CHEBI:33598 carbocyclic compound
CHEBI:33836 benzenoid aromatic compound
CHEBI:22712 benzenes
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:134043 phenylureas
CHEBI:133818 HG-9-91-01
CHEBI:33659 organic aromatic compound
CHEBI:33836 benzenoid aromatic compound
CHEBI:22712 benzenes
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:134043 phenylureas
CHEBI:133818 HG-9-91-01
CHEBI:35618 aromatic ether
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:33860 aromatic amine
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:24532 organic heterocyclic compound
CHEBI:25693 organic heteromonocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:38101 organonitrogen heterocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:50047 organic amino compound
CHEBI:33860 aromatic amine
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:50996 tertiary amino compound
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:50995 secondary amino compound
CHEBI:133818 HG-9-91-01
CHEBI:33304 chalcogen molecular entity
CHEBI:36962 organochalcogen compound
CHEBI:36963 organooxygen compound
CHEBI:25698 ether
CHEBI:35618 aromatic ether
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:25806 oxygen molecular entity
CHEBI:36963 organooxygen compound
CHEBI:25698 ether
CHEBI:35618 aromatic ether
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:33302 pnictogen molecular entity
CHEBI:51143 nitrogen molecular entity
CHEBI:35352 organonitrogen compound
CHEBI:38101 organonitrogen heterocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:50047 organic amino compound
CHEBI:33860 aromatic amine
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:50996 tertiary amino compound
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:50995 secondary amino compound
CHEBI:133818 HG-9-91-01
CHEBI:32988 amide
CHEBI:33256 primary amide
CHEBI:47857 ureas
CHEBI:134043 phenylureas
CHEBI:133818 HG-9-91-01
CHEBI:36357 polyatomic entity
CHEBI:25367 molecule
CHEBI:33595 cyclic compound
CHEBI:33597 homocyclic compound
CHEBI:33598 carbocyclic compound
CHEBI:33836 benzenoid aromatic compound
CHEBI:22712 benzenes
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:134043 phenylureas
CHEBI:133818 HG-9-91-01
CHEBI:33832 organic cyclic compound
CHEBI:33598 carbocyclic compound
CHEBI:33836 benzenoid aromatic compound
CHEBI:22712 benzenes
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:134043 phenylureas
CHEBI:133818 HG-9-91-01
CHEBI:33659 organic aromatic compound
CHEBI:33836 benzenoid aromatic compound
CHEBI:22712 benzenes
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:134043 phenylureas
CHEBI:133818 HG-9-91-01
CHEBI:35618 aromatic ether
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:33860 aromatic amine
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:24532 organic heterocyclic compound
CHEBI:25693 organic heteromonocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:38101 organonitrogen heterocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:33655 aromatic compound
CHEBI:33659 organic aromatic compound
CHEBI:33836 benzenoid aromatic compound
CHEBI:22712 benzenes
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:134043 phenylureas
CHEBI:133818 HG-9-91-01
CHEBI:35618 aromatic ether
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:33860 aromatic amine
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:5686 heterocyclic compound
CHEBI:24532 organic heterocyclic compound
CHEBI:25693 organic heteromonocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:38101 organonitrogen heterocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:33670 heteromonocyclic compound
CHEBI:25693 organic heteromonocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:33661 monocyclic compound
CHEBI:33670 heteromonocyclic compound
CHEBI:25693 organic heteromonocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:72695 organic molecule
CHEBI:33832 organic cyclic compound
CHEBI:33598 carbocyclic compound
CHEBI:33836 benzenoid aromatic compound
CHEBI:22712 benzenes
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:134043 phenylureas
CHEBI:133818 HG-9-91-01
CHEBI:33659 organic aromatic compound
CHEBI:33836 benzenoid aromatic compound
CHEBI:22712 benzenes
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:134043 phenylureas
CHEBI:133818 HG-9-91-01
CHEBI:35618 aromatic ether
CHEBI:51683 methoxybenzenes
CHEBI:51681 dimethoxybenzene
CHEBI:133818 HG-9-91-01
CHEBI:33860 aromatic amine
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:24532 organic heterocyclic compound
CHEBI:25693 organic heteromonocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:38101 organonitrogen heterocyclic compound
CHEBI:38313 diazines
CHEBI:39447 pyrimidines
CHEBI:38338 aminopyrimidine
CHEBI:133818 HG-9-91-01
CHEBI:26144 piperazines
CHEBI:46848
N
-arylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:46845
N
-alkylpiperazine
CHEBI:133818 HG-9-91-01
CHEBI:50906 role
CHEBI:24432 biological role
CHEBI:35222 inhibitor
CHEBI:23924 enzyme inhibitor
CHEBI:71300 EC 2.* (transferase) inhibitor
CHEBI:76668 EC 2.7.* (
P
-containing group transferase) inhibitor
CHEBI:37699 protein kinase inhibitor
CHEBI:133891 salt-inducible kinase 2 inhibitor
CHEBI:133818 HG-9-91-01
CHEBI:52206 biochemical role
CHEBI:23924 enzyme inhibitor
CHEBI:71300 EC 2.* (transferase) inhibitor
CHEBI:76668 EC 2.7.* (
P
-containing group transferase) inhibitor
CHEBI:37699 protein kinase inhibitor
CHEBI:133891 salt-inducible kinase 2 inhibitor
CHEBI:133818 HG-9-91-01
CHEBI:33232 application
CHEBI:52217 pharmaceutical
CHEBI:23888 drug
CHEBI:35610 antineoplastic agent
CHEBI:133818 HG-9-91-01
Relationship Types
is a
has part
is conjugate base of
is conjugate acid of
is tautomer of
is enantiomer of
has functional parent
has parent hydride
is substituent group from
has role
Status
Checked
Unchecked