CHEBI:138889 - 6-diazo-5-oxo-L-norleucine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name 6-diazo-5-oxo-L-norleucine
ChEBI ID CHEBI:138889
ChEBI ASCII Name 6-diazo-5-oxo-L-norleucine
Definition A non-proteinogenic L-α-amino acid that is L-norleucine which is substituted at position 5 by an oxo group and at position 6 by a diazo group. It is as inhibitor of various glutamine-utilising enzymes.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Sandra Orchard
Supplier Information
Download Molfile XML SDF
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): antimetabolite
A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
glutamine antagonist
An antagonist that acts on glutamine receptors.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
EC 6.3.4.2 [CTP synthase (glutamine hydrolyzing)] inhibitor
Any EC 6.3.4.* (other carbonnitrogen ligases) inhibitor that interferes with the action of CTP synthase (glutamine hydrolyzing) (EC 6.3.4.2).
EC 6.3.5.3 (phosphoribosylformylglycinamidine synthase) inhibitor
Any EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of phosphoribosylformylglycinamidine synthase (EC 6.3.5.3).
EC 6.3.5.2 [GMP synthase (glutamine-hydrolysing)] inhibitor
An EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2).
bacterial metabolite
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
analgesic
An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
antiviral agent
A substance that destroys or inhibits replication of viruses.
EC 6.3.5.5 [carbamoyl-phosphate synthase (glutamine-hydrolysing)] inhibitor
An EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5).
EC 2.4.2.14 (amidophosphoribosyltransferase) inhibitor
Any EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of amidophosphoribosyltransferase (EC 2.4.2.14).
EC 3.5.1.2 (glutaminase) inhibitor
Any EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the activity of a glutaminase (EC 3.5.1.2) and thus the generation of glutamate from glutamine.
EC 6.3.5.1 [NAD(+) synthase (glutamine-hydrolysing)] inhibitor
Any EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of NAD+ synthase (glutamine-hydrolysing) (EC 6.3.5.1).
EC 6.3.5.4 [asparagine synthase (glutamine-hydrolysing)] inhibitor
Any EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of asparagine synthase (glutamine-hydrolysing), EC 6.3.5.4.
Application(s): analgesic
An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
Related Structures
6-diazo-5-oxo-L-norleucine is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
6-diazo-5-oxo-L-norleucine is a Tautomer of
6-diazo-5-oxo-L-norleucine zwitterion
Mass : 171.156
183231
Graph View Tree View
panning
Move up
Move left
Move down
Move right
Graph compression

Simplified view Show me the possible minimal nodes in this graph
Full view Show me all the nodes in this graph
Personalised view Create your own personalised ontology view, if you wish to remove any entity from your future visualisations please right click the entity (e.g. molecular entity)
My hidden entities
Edit
+Zoom in
-Zoom out
Download
Enter fullscreen