CHEBI:146245 - SR 144528

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ChEBI Name SR 144528
ChEBI ID CHEBI:146245
Definition A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)-1H-pyrazole-3-carboxylic acid with the amino group of (1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-amine. A potent and selective cannabinoid receptor type 2 (CB2 receptor) inverse agonist (Ki = 0.6 nM).
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Ceri
Supplier Information
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Roles Classification
Biological Role(s): CB2 receptor antagonist
An antagonist that binds to and deactivates type 2 cannabinoid receptors.
EC 2.3.1.26 (sterol O-acyltransferase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of acyl-CoA:cholesterol acyltransferase (EC 2.3.1.26).
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