CHEBI:167176 - GRL-0617

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ChEBI Name GRL-0617
ChEBI ID CHEBI:167176
Definition A benzamide resulting from the formal condensation of the carboxy group of 5-amino-2-methylbenzoic acid with the amino group of (1R)-1-(naphthalen-1-yl)ethan-1-amine. It is a potent noncovalent inhibitor (IC50 = 600 nM) of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro).
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Margaret Duesbury
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): anticoronaviral agent
Any antiviral agent which inhibits the activity of coronaviruses.
protease inhibitor
A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases).
Related Structures
GRL-0617 is a Functional Parent of
KOM70144
Mass : 346.430
Formula : C22H22N2O2
167314
GRL-0617 is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
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