CHEBI:177372 - naxagolide

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ChEBI Name naxagolide
ChEBI ID CHEBI:177372
Definition An organic heterotricyclic compound that is (4aR,10bR)-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazine substituted by propyl and hydroxy groups at positions 4 and 9, respectively. It is a potent dopamine D2-receptor agonist and its hydrochloride salt was under clinical development by Merck & Co as a potential antiparkinsonian agent (now discontinued).
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Stan Laulederkind
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): dopamine agonist
A drug that binds to and activates dopamine receptors.
Application(s): antiparkinson drug
A drug used in the treatment of Parkinson's disease.
dopamine agonist
A drug that binds to and activates dopamine receptors.
anticonvulsant
A drug used to prevent seizures or reduce their severity.
Related Structures
naxagolide is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
naxagolide is a Conjugate Base of
naxagolide(1+)
Mass : 248.345
Formula : C15H22NO2
177380
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