CHEBI:189648 - PB28

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ChEBI Name PB28
ChEBI ID CHEBI:189648
Definition A member of the class of tetralins that is tetralin that is substituted by 3-(4-cyclohexylpiperazin-1-yl)propyl and methoxy groups at positions 1 and 5, respectively. It is a sigma 2 (σ2) receptor agonist (Ki = 0.68 nM) and exhibits antineoplastic and anti SARS-CoV-2 activities.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Jinyang Du
Supplier Information
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Roles Classification
Biological Role(s): anticoronaviral agent
Any antiviral agent which inhibits the activity of coronaviruses.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
sigma-2 receptor agonist
A sigma receptor modulator that activates the sigma-2 receptor.
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