CHEBI:189659 - PF-06446846

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name PF-06446846
ChEBI ID CHEBI:189659
Definition A triazolopyridine that is 3H-[1,2,3]triazolo[4,5-b]pyridine substituted by a 4-{(3-chloropyridin-2-yl)[(3R)-piperidin-3-yl]carbamoyl}phenyl group at position 3. It is a potent inhibitor of PCSK9.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Jinyang Du
Supplier Information
Download Molfile XML SDF
Roles Classification
Biological Role(s): EC 3.4.21.61 (kexin) inhibitor
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of kexin (EC 3.4.21.61).
Application(s): antilipemic drug
A substance used to treat hyperlipidemia (an excess of lipids in the blood).
Graph View Tree View
panning
Move up
Move left
Move down
Move right
Graph compression

Simplified view Show me the possible minimal nodes in this graph
Full view Show me all the nodes in this graph
Personalised view Create your own personalised ontology view, if you wish to remove any entity from your future visualisations please right click the entity (e.g. molecular entity)
My hidden entities
Edit
+Zoom in
-Zoom out
Download
Enter fullscreen