CHEBI:189668 - varespladib

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ChEBI Name varespladib
ChEBI ID CHEBI:189668
Definition A member of the class of indoles that is 1H-indole substituted by benzyl, ethyl, oxamoyl, and carboxymethoxy groups at positions 1, 2, 3, and 4, respectively. It is an oral secretory phospholipase A2 inhibitor and exhibits anti-inflammatory effects.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): EC 3.1.1.4 (phospholipase A2) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of phospholipase A2 (EC 3.1.1.4).
Application(s): anti-inflammatory drug
A substance that reduces or suppresses inflammation.
antidote
Any protective agent counteracting or neutralizing the action of poisons.
Related Structures
varespladib is a Functional Parent of
varespladib methyl
Mass : 394.427
Formula : C22H22N2O5
192805
varespladib is a Conjugate Acid of
varespladib(1-)
Mass : 379.393
Formula : C21H19N2O5
189666
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