CHEBI:228209 - KU-55933

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ChEBI Name KU-55933
ChEBI ID CHEBI:228209
Definition A member of the class of thianthrenes that is thianthrene substituted by a 6-(morpholin-4-yl)-4-oxo-4H-pyran-2-yl group at position 1. It is potent inhibitor of ATM kinase.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:91372
Supplier Information
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Roles Classification
Biological Role(s): EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
autophagy inducer
Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
Application(s): radiosensitizing agent
A drug that makes increases the sensitivity of tumour cells to radiation therapy.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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