CHEBI:2639 - amiloride

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ChEBI Name amiloride
ChEBI ID CHEBI:2639
Definition A member of the class of pyrazines resulting from the formal monoacylation of guanidine with the carboxy group of 3,5-diamino-6-chloropyrazine-2-carboxylic acid.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:47210
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): sodium channel blocker
An agent that inhibits sodium influx through cell membranes.
Application(s): diuretic
An agent that promotes the excretion of urine through its effects on kidney function.
Related Structures
amiloride is a Functional Parent of
5-(N,N-hexamethylene)amiloride
Mass : 311.77100
Formula : C12H18ClN7O
76400
5-(N-methyl-N-propyl)amiloride
Mass : 285.734
Formula : C10H16ClN7O
138016
ethylisopropylamiloride
Mass : 299.760
Formula : C11H18ClN7O
136538
amiloride is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
amiloride is a Conjugate Base of
amiloride(1+)
Mass : 230.63400
Formula : C6H9ClN7O
84745
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Relationship Types
is a
has part
is conjugate base of
is conjugate acid of
is tautomer of
is enantiomer of
has functional parent
has parent hydride
is substituent group from
has role
Status
Checked
Unchecked