CHEBI:27953 - physostigmine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name physostigmine
ChEBI ID CHEBI:27953
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:8187, CHEBI:26108
Supplier Information
Download Molfile XML SDF
Roles Classification
Biological Role(s): EC 3.1.1.8 (cholinesterase) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
miotic
An agent causing contraction of the pupil of the eye. Because the size of the pupil is under the antagonistic control of the sympathetic and parasympathetic systems, drugs affecting either system can cause miosis. Drugs that mimic or potentiate the parasympathetic input to the circular constrictor muscle and drugs that inhibit sympathetic input to the radial dilator muscle tend to contract the pupils.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Application(s): antidote to curare poisoning
A role borne by a molecule that acts to counteract or neutralize the deleterious effects of curare.
miotic
An agent causing contraction of the pupil of the eye. Because the size of the pupil is under the antagonistic control of the sympathetic and parasympathetic systems, drugs affecting either system can cause miosis. Drugs that mimic or potentiate the parasympathetic input to the circular constrictor muscle and drugs that inhibit sympathetic input to the radial dilator muscle tend to contract the pupils.
Related Structures
physostigmine is a Structural Derivative of
carbamic acid
Mass : 61.04006
Formula : CH3NO2
28616
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