CHEBI:28787 - nitroglycerin

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ChEBI Name nitroglycerin
ChEBI ID CHEBI:28787
Definition A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:7595, CHEBI:25559
Supplier Information
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Roles Classification
Chemical Role(s): nitric oxide donor
An agent, with unique chemical structure and biochemical requirements, which generates nitric oxide.
explosive
A substance capable of undergoing rapid and highly exothermic decomposition.
Biological Role(s): xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
Application(s): vasodilator agent
A drug used to cause dilation of the blood vessels.
tocolytic agent
Any compound used to suppress premature labour and immature birth by suppressing uterine contractions.
muscle relaxant
A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis.
prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
Related Structures
nitroglycerin is a Structural Derivative of
glycerol
Mass : 92.09382
Formula : C3H8O3
17754
nitric acid
Mass : 63.01280
Formula : HNO3 HNO3
48107
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Relationship Types
is a
has part
is conjugate base of
is conjugate acid of
is tautomer of
is enantiomer of
has functional parent
has parent hydride
is substituent group from
has role
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